Sugi Predict

Sugi Predict / Compounds / SCHEMBL4388677

SCHEMBL4388677

SCHEMBL4388677

Cc1cc2c(cc1C)CC(N)C2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FYN P06241 1/20 0.56
▸ CA1 P00915 3/20 0.42
▸ CA2 P00918 3/20 0.42
▸ CA12 O43570 2/20 0.42
▸ CA7 P43166 2/20 0.42
▸ CA14 Q9ULX7 2/20 0.42
▸ MAPT P10636 3/20 0.41
▸ NFKB1 P19838 1/20 0.41
▸ THPO P40225 1/20 0.41
▸ HIF1A Q16665 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ USP2 O75604 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.40
▸ DRD2 P14416 2/20 0.38
▸ DRD3 P35462 2/20 0.38
▸ ADRA1A P35348 1/20 0.34
▸ PLAU P00749 1/20 0.34
▸ CYP3A4 P08684 1/20 0.33
▸ TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12269945 0.84 FYN (0.46) FYNCA1CA2CA12CA7
SCHEMBL5314853 0.80 ADRA1A (0.48) FYNCA1CA2MAPTALDH1A1
SCHEMBL22787541 0.75 CA1 (0.50) FYNCA1CA2CA12CA7
SCHEMBL294181 0.75 CA1 (0.50) FYNCA1CA2CA12CA7
SCHEMBL23519694 0.74 FYN (0.59) FYNCA1CA2CA12CA7
SCHEMBL3659349 0.74 MAPT (0.33) MAPTALDH1A1TSHRNPC1RAB9A
Hydrochloric Acid SCHEMBL10599854 0.73 HTR7 (0.36) —
SCHEMBL22092917 0.72 FYN (0.56) FYNCA1CA2CA12CA7
SCHEMBL22815693 0.72 FYN (0.56) FYNCA1CA2CA12CA7
SCHEMBL29992505 0.72 FYN (0.56) FYNCA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500301-B Regulator for longitudinal behavior 以西结·戈兰 2024-02-13 — — CN claimed
US-12350242-B2 Binge behavior regulators Clearmind Medicine Inc. (CA) 2025-07-08 — — US disclosed
EP-4522596-A1 DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS C4X Discovery Limited (GB) 2025-03-19 — — EP disclosed
CN-119497712-A Indane derivatives as MALT1 inhibitors 希四克斯探索有限公司 2025-02-21 — — CN disclosed
US-12064402-B2 Binge behavior regulators Clearmind Medicine Inc. (CA) 2024-08-20 — — US disclosed
CN-112500301-B Regulator for longitudinal behavior 以西结·戈兰 2024-02-13 — — CN disclosed
WO-2023218203-A1 DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS C4X DISCOVERY LIMITED (GB) 2023-11-16 — — WO disclosed
US-20230092839-A1 ALCOHOLIC BEVERAGE SUBSTITUTES Clearmind Medicine Inc. (CA) 2023-03-23 — — US disclosed
US-11528924-B2 Alcoholic beverage substitutes Clearmind Medicine, Inc. (CA) 2022-12-20 — — US disclosed
CN-114903134-A Alcoholic beverage substitute 以西结·戈兰 2022-08-16 — — CN disclosed
US-8344004-B2 Cyclic pyridyl-N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals SANOFI (FR) 2013-01-01 — — US disclosed
US-8344004-B2 Cyclic pyridyl-N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals SANOFI (FR) 2013-01-01 — — US disclosed
US-20110224263-A1 Cyclic pyridyl-N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals SANOFI-AVENTIS (FR) 2011-09-15 — — US disclosed
US-20110224263-A1 Cyclic pyridyl-N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals SANOFI-AVENTIS (FR) 2011-09-15 — — US disclosed
EP-1791820-B1 ENANTIOSELECTIVE PREPARATION OF QUINOLINE DERIVATIVES NOVARTIS AG (CH) 2009-12-02 — — EP disclosed
US-20090238770-A1 Organic compounds NOVARTIS AG (CH) 2009-09-24 — — US disclosed
WO-2009080223-A1 CYCLIC PYRIDYL-N-(1,3,4)-THIADIAZOL-2-YL-BENZENE SULFONAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS SANOFI-AVENTIS (FR) 2009-07-02 — — WO disclosed
US-5708018-A 2-aminoindans as selective dopamine D3 ligands PHARMACIA & UPJOHN COMPANY (US) 1998-01-13 — — US disclosed
EP-0712387-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS PHARMACIA & UPJOHN COMPANY (US) 1996-05-22 — — EP disclosed
WO-1995004713-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS THE UPJOHN COMPANY (US) 1995-02-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230092839-A1 ALCOHOLIC BEVERAGE SUBSTITUTES ADH1A, ADH5, ADH1C FYN 3559/4885CA1 1091/4885CA2 947/4885
US-20090238770-A1 Organic compounds LTB4R, LTB4R2, LTA4H FYN 1690/4885CA1 473/4885CA2 364/4885
US-12350242-B2 Binge behavior regulators GABRB3, GABRB2, GABRB1 FYN 4855/4885CA1 2927/4885CA2 4535/4885
US-12064402-B2 Binge behavior regulators GABRB3, GABRB2, GABRB1 FYN 4855/4885CA1 2927/4885CA2 4535/4885
US-11528924-B2 Alcoholic beverage substitutes ADH1A, ADH5, ADH1C FYN 3559/4885CA1 1091/4885CA2 947/4885
US-20110224263-A1 Cyclic pyridyl-N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals PPARD, PPARG, PPARA FYN 2183/4885CA1 4820/4885CA2 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.