SCHEMBL294181

SCHEMBL294181

Cc1ccc2c(c1)CC(N)C2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA12 O43570 2/20 0.50
CA7 P43166 2/20 0.50
CA14 Q9ULX7 2/20 0.50
FYN P06241 1/20 0.48
AADAT Q8N5Z0 2/20 0.42
DRD2 P14416 2/20 0.42
DRD3 P35462 2/20 0.42
ACHE P22303 1/20 0.41
OPRK1 P41145 1/20 0.41
PLAU P00749 1/20 0.39
METAP1 P53582 1/20 0.37
NFKB1 P19838 1/20 0.36
THPO P40225 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22787541 1.00 CA1 (0.50) CA1CA2CA12CA7CA14
SCHEMBL23607149 0.84 DRD2 (0.62) DRD2DRD3ACHEOPRK1PLAU
SCHEMBL13189198 0.84 OPRK1 (0.62) DRD2DRD3OPRK1PLAUNFKB1
SCHEMBL13961200 0.82 ACHE (0.41) CA1CA2CA12CA7CA14
SCHEMBL31236154 0.79 ACHE (0.47) AADATACHEMETAP1ALDH1A1MAPT
SCHEMBL27246033 0.79 ACHE (0.47) AADATACHEMETAP1ALDH1A1MAPT
SCHEMBL80428 0.79 ACHE (0.47) AADATACHEMETAP1ALDH1A1MAPT
SCHEMBL30930042 0.79 ACHE (0.47) AADATACHEMETAP1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL6642057 0.78 NFE2L2 (0.43) CA1CA2CA12CA7CA14
Hydrochloric Acid SCHEMBL6642061 0.78 NFE2L2 (0.43) CA1CA2CA12CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500301-B Regulator for longitudinal behavior 以西结·戈兰 2024-02-13 CN claimed
US-20250288541-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2025-09-18 US disclosed
US-12357590-B2 Binge behavior regulators Clearmind Medicine Inc. (CA) 2025-07-15 US disclosed
US-12350242-B2 Binge behavior regulators Clearmind Medicine Inc. (CA) 2025-07-08 US disclosed
WO-2024141998-A1 METHOD OF TREATING TAUOPATHIES GT GAIN THERAPEUTICS SA (CH) 2024-07-04 WO disclosed
WO-2024062395-A1 USE OF 5-METHOXY-2-AMINOINDAN (\"MEAI\") IN METHODS FOR TREATING METABOLIC SYNDROME Clearmind Medicine Inc. (IL) 2024-03-28 WO disclosed
CN-112500301-B Regulator for longitudinal behavior 以西结·戈兰 2024-02-13 CN disclosed
US-11780826-B2 Bisamide sarcomere activating compounds and uses thereof AMGEN INC. (US) 2023-10-10 US disclosed
WO-2023154282-A1 COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS THERAS, INC. (US) 2023-08-17 WO disclosed
US-20230218597-A1 SUBSTITUTED PYRIDINES AND METHODS OF USE THERAVANCE BIOPHARMA R&D IP LLC (US) 2023-07-13 US disclosed
US-20080255239-A1 SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS ALLERGAN, INC. 2008-10-16 US disclosed
US-20070161645-A1 Thiazole inhibitors targeting resistant kinase mutations TARGEGEN, INC. (US) 2007-07-12 US disclosed
US-20070149508-A1 Six membered heteroaromatic inhibitors targeting resistant kinase mutations TARGEGEN, INC. (US) 2007-06-28 US disclosed
WO-2007056023-A2 THIAZOLE INHIBITORS TARGETING RESISTANT KINASE MUTATIONS TARGEGEN, INC. (US) 2007-05-18 WO disclosed
WO-2007056075-A2 SIX MEMBERED HETEROAROMATIC INHIBITORS TARGETING RESISTANT KINASE MUTATIONS TARGEGEN, INC. (US) 2007-05-18 WO disclosed
US-5708018-A 2-aminoindans as selective dopamine D3 ligands PHARMACIA & UPJOHN COMPANY (US) 1998-01-13 US disclosed
EP-0712387-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS PHARMACIA & UPJOHN COMPANY (US) 1996-05-22 EP disclosed
WO-1995004713-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS THE UPJOHN COMPANY (US) 1995-02-16 WO disclosed
US-4861789-A Dihydro-indene-amine-dihydrooxazoles BEECHAM GROUP PLC (GB) 1989-08-29 US disclosed
EP-0251453-A2 Substituted amino-dihydrooxazoles, -thiazoles and -imidazoles, process for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1988-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250288541-A1 BINGE BEHAVIOR REGULATORS GABRB3, GABRB2, GABRB1 CA1 2927/4885CA2 4535/4885CA12 4657/4885
US-11780826-B2 Bisamide sarcomere activating compounds and uses thereof TNNI3, TNNT2, TNNC1 CA1 3966/4885CA2 257/4885CA12 4676/4885
US-12350242-B2 Binge behavior regulators GABRB3, GABRB2, GABRB1 CA1 2927/4885CA2 4535/4885CA12 4657/4885
US-20070161645-A1 Thiazole inhibitors targeting resistant kinase mutations JAK2, ABL1, FLT3 CA1 4859/4885CA2 3797/4885CA12 4829/4885
US-20080255239-A1 SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS ADRB2, ADRA2A, ADRA2C CA1 3884/4885CA2 2190/4885CA12 4457/4885
US-20070149508-A1 Six membered heteroaromatic inhibitors targeting resistant kinase mutations ABL1, KDR, BCR CA1 4880/4885CA2 4647/4885CA12 4807/4885
US-12357590-B2 Binge behavior regulators GABRB3, GABRB2, GABRB1 CA1 2927/4885CA2 4535/4885CA12 4657/4885
US-20230218597-A1 SUBSTITUTED PYRIDINES AND METHODS OF USE ALK, ACVR1, ACVR2A CA1 2977/4885CA2 1533/4885CA12 2752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.