Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682052 | 0.77 | CA12 (0.31) | CA12CA2CA9 | |
| SCHEMBL11682325 | 0.77 | L3MBTL1 (0.33) | CA12CA2CA9KDM4E | |
| SCHEMBL11520455 | 0.77 | CA12 (0.31) | CA12CA2CA9 | |
| SCHEMBL4404057 | 0.75 | BBOX1 (0.46) | KDM4EMAPTALOX15BBOX1 | |
| SCHEMBL13672692 | 0.72 | — | — | |
| SCHEMBL4412450 | 0.72 | GMNN (0.43) | CA12CA9KDM4EMAPTALOX15 | |
| SCHEMBL13672698 | 0.70 | — | — | |
| SCHEMBL13672691 | 0.70 | — | — | |
| SCHEMBL11526263 | 0.70 | CA12 (0.33) | CA12CA2CA9 | |
| SCHEMBL11686152 | 0.70 | CA12 (0.33) | CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922389-B1 | ABSORBENT COMPOSITION CONTAINING MOLECULES WITH A HINDERED AMINE AND A METAL SULFONATE STRUCTURE FOR ACID GAS SCRUBBING PROCESS | EXXONMOBIL RES & ENG CO (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-2825286-A1 | AMINE TREATING PROCESS FOR ACID GAS SEPARATION USING BLENDS OF AMINES AND ALKYLOXYAMINES | ExxonMobil Research and Engineering Company (US) | 2015-01-21 | — | — | EP | disclosed |
| WO-2013138443-A1 | AMINE TREATING PROCESS FOR ACID GAS SEPARATION USING BLENDS OF AMINES AND ALKYLOXYAMINES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-09-19 | — | — | WO | disclosed |
| US-20130243676-A1 | AMINE TREATING PROCESS FOR ACID GAS SEPARATION USING BLENDS OF AMINES AND ALKYLOXYAMINES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-09-19 | — | — | US | disclosed |
| US-8480795-B2 | Absorbent composition containing molecules with a hindered amine and a metal sulfonate, phosphonate or carboxylate structure for acid gas scrubbing process | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-07-09 | — | — | US | disclosed |
| US-20090308248-A1 | Absorbent composition containing molecules with a hindered amine and a metal sulfonate, phosphonate or carboxylate structure for acid gas scrubbing process | SISKIN MICHAEL | 2009-12-17 | — | — | US | disclosed |
| EP-1922389-A1 | ABSORBENT COMPOSITION CONTAINING MOLECULES WITH A HINDERED AMINE AND A METAL SULFONATE, PHOSPHONATE OR CARBOXYLATE STRUCTURE FOR ACID GAS SCRUBBING PROCESS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007021531-A1 | ABSORBENT COMPOSITION CONTAINING MOLECULES WITH A HINDERED AMINE AND A METAL SULFONATE, PHOSPHONATE OR CARBOXYLATE STRUCTURE FOR ACID GAS SCRUBBING PROCESS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-02-22 | — | — | WO | disclosed |
| EP-0315204-A2 | Bleaching composition | LION CORPORATION (JP) | 1989-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090308248-A1 | Absorbent composition containing molecules with a hindered amine and a metal sulfonate, phosphonate or carboxylate structure for acid gas scrubbing process | CBS, MPST, TST | CA12 12/4885CA2 79/4885CA9 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.