Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RHEB | Q15382 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860105 | 1.00 | GAA (0.53) | GAAHTTRHEBGRIN2DGRIN3B | |
| Benzimidazole SCHEMBL7020475 | 0.80 | PDE10A (0.42) | GAAHTTRHEBGRIN2DGRIN3B | |
| SCHEMBL577623 | 0.77 | GAA (0.57) | GAAHTTRHEBGRIN2DGRIN3B | |
| SCHEMBL15825576 | 0.77 | AMY1A (0.33) | GAAHTTLMNAMEN1RAB9A | |
| SCHEMBL9305390 | 0.75 | GAA (0.43) | GAAHTTRHEBGRIN2DGRIN3B | |
| SCHEMBL9305399 | 0.75 | GAA (0.43) | GAAHTTGRIN2DGRIN3BLMNA | |
| SCHEMBL9305060 | 0.75 | ALDH1A1 (0.61) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9305046 | 0.75 | F7 (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1006779 | 0.74 | FABP6 (0.59) | MEN1NPC1RAB9AKMT2AHRH4 | |
| SCHEMBL7393275 | 0.74 | GAA (0.53) | GAAHTTRHEBGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375235-B2 | Process for preparing substituted benzimidazole compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-20 | — | — | US | claimed |
| US-20050261211-A1 | Process for preparing substituted benzimidazole compounds | GLAXOSMITHKLINE LLC | 2005-11-24 | — | — | US | claimed |
| EP-1584620-A1 | Process for preparing substituted benzimidazole compounds | GLAXO GROUP LIMITED (GB) | 2005-10-12 | — | — | EP | claimed |
| EP-1272473-B1 | PROCESS FOR PREPARING SUBSTITUTED BENZIMIDAZOLE COMPOUNDS | GLAXO GROUP LTD (GB) | 2005-06-29 | — | — | EP | claimed |
| JP-2003530385-A | — | — | 2003-10-14 | — | — | JP | claimed |
| US-20030191127-A1 | Process for preparing substituted benzimidazole compounds | GLAXOSMITHKLINE LLC | 2003-10-09 | — | — | US | claimed |
| EP-1272473-A1 | PROCESS FOR PREPARING SUBSTITUTED BENZIMIDAZOLE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2003-01-08 | — | — | EP | claimed |
| EP-0845001-B1 | 5'-SUBSTITUTED-RIBOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | UNIV MICHIGAN (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001077083-A1 | PROCESS FOR PREPARING SUBSTITUTED BENZIMIDAZOLE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2001-10-18 | — | — | WO | claimed |
| US-5874413-A | CYTOMEGALO VIRUS | UNIVERSITY OF MICHIGAN (US) | 1999-02-23 | — | — | US | claimed |
| US-20260108495-A1 | VIRAL INHIBITORS, THE SYNTHESIS THEROF, AND INTERMEDIATES THERETO | TAKEDA PHARMACEUTICALS CO (JP) | 2026-04-23 | — | — | US | disclosed |
| US-20260097018-A1 | VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-04-09 | — | — | US | disclosed |
| US-20260076946-A1 | VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-03-19 | — | — | US | disclosed |
| US-20260076945-A1 | VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-03-19 | — | — | US | disclosed |
| US-12527771-B2 | Viral inhibitors, the synthesis thereof, and intermediates thereto | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-01-20 | — | — | US | disclosed |
| US-5360795-A | Treating cytomegalo virus and herpes simplex viruses | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1994-11-01 | — | — | US | disclosed |
| WO-1994008456-A1 | POLYSUBSTITUTED BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5248672-A | POLYSUBSTITUTED BENZIMIDAZOLE NUCLEOSIDES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0556334-A1 | POLYSUBSTITUTED BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007867-A1 | POLYSUBSTITUTED BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1992-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260076946-A1 | VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | TPMT, MPST, PCMT1 | GAA 2561/4885HTT 2378/4885RHEB 493/4885 |
| US-12527771-B2 | Viral inhibitors, the synthesis thereof, and intermediates thereto | IRF3, RPL12, MCM4 | GAA 1589/4885HTT 4624/4885RHEB 858/4885 |
| US-20260097018-A1 | VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | TPMT, PCMT1, RPL7 | GAA 2824/4885HTT 2995/4885RHEB 1588/4885 |
| US-20260076945-A1 | VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | PCMT1, MPST, TPMT | GAA 2387/4885HTT 2561/4885RHEB 1385/4885 |
| US-20030191127-A1 | Process for preparing substituted benzimidazole compounds | EIF2AK2, SAMHD1, ZC3HAV1 | GAA 200/4885HTT 4194/4885RHEB 3074/4885 |
| US-20050261211-A1 | Process for preparing substituted benzimidazole compounds | EIF2AK2, SAMHD1, ZC3HAV1 | GAA 200/4885HTT 4194/4885RHEB 3074/4885 |
| US-20260108495-A1 | VIRAL INHIBITORS, THE SYNTHESIS THEROF, AND INTERMEDIATES THERETO | HYOU1, CYP2F1, HAVCR2 | GAA 524/4885HTT 1729/4885RHEB 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.