Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907108 | 0.74 | — | — | |
| SCHEMBL9644150 | 0.72 | ALDH1A1 (0.32) | L3MBTL1ALDH1A1ALOX15HPGDMAPT | |
| SCHEMBL6129249 | 0.67 | L3MBTL1 (0.32) | L3MBTL1ALDH1A1ALOX15HPGDMAPT | |
| SCHEMBL10446742 | 0.65 | APAF1 (0.39) | L3MBTL1ALDH1A1ALOX15HPGDMAPT | |
| SCHEMBL28059928 | 0.64 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1ALOX15HPGDMAPT | |
| SCHEMBL247419 | 0.64 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1ALOX15HPGDMAPT | |
| SCHEMBL6129246 | 0.63 | L3MBTL1 (0.32) | L3MBTL1ALDH1A1ALOX15HPGDMAPT | |
| SCHEMBL120459 | 0.63 | SMN1; SMN2 (0.40) | L3MBTL1ALDH1A1ALOX15HPGDMAPT | |
| SCHEMBL13433876 | 0.61 | APAF1 (0.35) | L3MBTL1ALDH1A1ALOX15HPGDMAPT | |
| SCHEMBL30912996 | 0.61 | APAF1 (0.35) | ALDH1A1HPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240041726-A1 | FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION | CHATTEM, INC. | 2024-02-08 | — | — | US | claimed |
| EP-4231985-A1 | FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION | Chattem, Inc. (US) | 2023-08-30 | — | — | EP | claimed |
| CN-116322613-A | Foamable composition, use thereof and method for the production thereof | 查泰姆公司 | 2023-06-23 | — | — | CN | claimed |
| WO-2022087343-A1 | FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION | CHATTEM, INC. (US) | 2022-04-28 | — | — | WO | claimed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | claimed |
| EP-3169365-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF ITCH | Westfälische Wilhelms-Universität Münster (DE) | 2017-05-24 | — | — | EP | claimed |
| US-9320705-B2 | Sensation modifying topical composition foam | FOAMIX PHARMACEUTICALS LTD. (IL) | 2016-04-26 | — | — | US | claimed |
| WO-2015169884-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF ITCH | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) | 2015-11-12 | — | — | WO | claimed |
| EP-2614860-A2 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DRY EYE | Universidad Miguel Hernández De Elche (ES) | 2013-07-17 | — | — | EP | claimed |
| US-20120237453-A1 | SENSATION MODIFYING TOPICAL COMPOSITION FOAM | FOAMIX LTD. (IL) | 2012-09-20 | — | — | US | claimed |
| WO-2008138162-A1 | COMPOSITIONS AND THEIR USE | GIVAUDAN SA (CH) | 2008-11-20 | — | — | WO | claimed |
| US-20080253973-A1 | SENSATION MODIFYING TOPICAL COMPOSITION FOAM | FOAMIX LTD. (IL) | 2008-10-16 | — | — | US | claimed |
| US-20050000529-A1 | Method and compositions for imparting cooling effect to tobacco products | VECTOR TOBACCO INC. | 2005-01-06 | — | — | US | claimed |
| US-20040052828-A1 | Consumable product including consumable component and alpha-keto enamine derivatives | NESTEC S.A. (CH) | 2004-03-18 | — | — | US | claimed |
| US-6592884-B2 | Food, cosmetics, drugs; cooling skin, mouth | NESTEC S.A. (CH) | 2003-07-15 | — | — | US | claimed |
| US-20020022039-A1 | Method of using alpha-keto enamine derivatives as ingredients and products incorporating same | NESTEC S.A. (CH) | 2002-02-21 | — | — | US | claimed |
| WO-2025222091-A9 | POLY INFLAMMATORY KINASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2026-04-30 | — | — | WO | disclosed |
| US-20260069579-A1 | COMPOSITIONS AND METHODS FOR PAIN RELIEF AND NUMBING | RELIEVE THERAPEUTICS PTE. LTD. (SG) | 2026-03-12 | — | — | US | disclosed |
| US-20020022039-A1 | Method of using alpha-keto enamine derivatives as ingredients and products incorporating same | NESTEC S.A. (CH) | 2002-02-21 | — | — | US | disclosed |
| EP-1157617-A2 | Use of alpha-keto enamine derivatives as ingredients | Société des Produits Nestlé S.A. (CH) | 2001-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040052828-A1 | Consumable product including consumable component and alpha-keto enamine derivatives | PKN2, OPRD1, PKN1 | L3MBTL1 3770/4885ALDH1A1 484/4885ALOX15 1502/4885 |
| US-20020022039-A1 | Method of using alpha-keto enamine derivatives as ingredients and products incorporating same | ECH1, KMO, PKN1 | L3MBTL1 3305/4885ALDH1A1 840/4885ALOX15 800/4885 |
| US-20260069579-A1 | COMPOSITIONS AND METHODS FOR PAIN RELIEF AND NUMBING | GABRE, GJB2, PMP22 | L3MBTL1 1417/4885ALDH1A1 1220/4885ALOX15 1692/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | L3MBTL1 3284/4885ALDH1A1 3726/4885ALOX15 3276/4885 |
| US-20080253973-A1 | SENSATION MODIFYING TOPICAL COMPOSITION FOAM | TRPA1, GPR35, TRPV1 | L3MBTL1 4878/4885ALDH1A1 2137/4885ALOX15 939/4885 |
| US-20120237453-A1 | SENSATION MODIFYING TOPICAL COMPOSITION FOAM | TRPA1, GPR35, TRPV1 | L3MBTL1 4878/4885ALDH1A1 2137/4885ALOX15 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.