Sugi Predict

Sugi Predict / Compounds / SCHEMBL4762280

SCHEMBL4762280

SCHEMBL4762280

CNC(=O)NC(=O)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 9/20 0.62
▸ NPC1 O15118 8/20 0.62
▸ MEN1 O00255 3/20 0.62
▸ KMT2A Q03164 3/20 0.62
▸ TP53 P04637 1/20 0.56
▸ ALDH1A1 P00352 3/20 0.53
▸ POLB P06746 2/20 0.53
▸ TDP1 Q9NUW8 1/20 0.53
▸ HDAC3 O15379 1/20 0.52
▸ CA12 O43570 1/20 0.52
▸ CA1 P00915 1/20 0.52
▸ IDO1 P14902 1/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ HDAC1 Q13547 1/20 0.52
▸ CA9 Q16790 1/20 0.52
▸ HDAC7 Q8WUI4 1/20 0.52
▸ HDAC2 Q92769 1/20 0.52
▸ HSD17B10 Q99714 1/20 0.52
▸ HDAC8 Q9BY41 1/20 0.52
▸ HDAC6 Q9UBN7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18163369 0.89 HDAC2 (0.60) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL6340484 0.86 RAB9A (0.72) RAB9ANPC1MEN1KMT2ATP53
SCHEMBL6100 0.86 HDAC8 (0.62) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL25489176 0.84 HDAC8 (0.61) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL7796539 0.84 HDAC8 (0.60) RAB9ANPC1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL2915137 0.84 HDAC8 (0.60) RAB9ANPC1MEN1KMT2AALDH1A1
Methane SCHEMBL15893673 0.84 HDAC8 (0.67) RAB9ANPC1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL5075431 0.84 HDAC8 (0.60) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL11130438 0.84 HDAC8 (0.60) RAB9ANPC1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL5866386 0.84 HDAC8 (0.60) RAB9ANPC1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080280988-A1 Use of (N'-Methyl) benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-13 — — US claimed
US-20080274884-A1 Novel use of (N'-methyl)benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 — — US claimed
US-10556889-B1 Salvinorin derivatives Blue Sky Pharmaceuticals, LLC (US) 2020-02-11 — — US disclosed
US-7468378-B2 Substituted quinoline compounds PFIZER INC. (US) 2008-12-23 — — US disclosed
US-20080280988-A1 Use of (N'-Methyl) benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-13 — — US disclosed
US-20080280988-A1 Use of (N'-Methyl) benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-13 — — US disclosed
JP-2008266187-A USE OF (N'-METHYL)BENZOYL UREA COMPOUND SUMITOMO CHEMICAL CO LTD 2008-11-06 — — JP disclosed
JP-2008266188-A USE OF (N'-METHYL)BENZOYL UREA COMPOUND SUMITOMO CHEMICAL CO LTD 2008-11-06 — — JP disclosed
US-20080274884-A1 Novel use of (N'-methyl)benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 — — US disclosed
US-20080274884-A1 Novel use of (N'-methyl)benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 — — US disclosed
US-20080274884-A1 Novel use of (N'-methyl)benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 — — US disclosed
JP-2007297375-A METHOD FOR PROTECTING PLANT SUMITOMO CHEMICAL CO LTD 2007-11-15 — — JP disclosed
WO-2007116949-A1 PLANT PROTECTION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-18 — — WO disclosed
WO-2007116948-A1 PLANT PROTECTION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-18 — — WO disclosed
US-20070093525-A1 Triamide-substituted heterobicyclic compounds PFIZER INC 2007-04-26 — — US disclosed
US-20060223851-A1 TRIAMIDE-SUBSTITUTED HETEROBICYCLIC COMPOUNDS BERTINATO PETER 2006-10-05 — — US disclosed
US-20050234099-A1 Substituted quinoline compounds PFIZER INC 2005-10-20 — — US disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 — — EP disclosed
EP-0504266-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT, INC. (US) 1992-09-23 — — EP disclosed
WO-1991009007-A2 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT, INC. (US) 1991-06-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274884-A1 Novel use of (N'-methyl)benzoylurea compound RNGTT, L3MBTL4, MYB RAB9A 914/4885NPC1 2420/4885MEN1 1701/4885
US-10556889-B1 Salvinorin derivatives OPRD1, OPRK1, OPRL1 RAB9A 1009/4885NPC1 1602/4885MEN1 4684/4885
US-20050234099-A1 Substituted quinoline compounds APOB, APOL1, MTPN RAB9A 1687/4885NPC1 32/4885MEN1 1437/4885
US-20080280988-A1 Use of (N'-Methyl) benzoylurea compound L3MBTL4, L3MBTL3, L3MBTL1 RAB9A 1993/4885NPC1 2538/4885MEN1 1282/4885
US-20060223851-A1 TRIAMIDE-SUBSTITUTED HETEROBICYCLIC COMPOUNDS APOB, MTPN, CTRB1 RAB9A 2095/4885NPC1 32/4885MEN1 1637/4885
US-20070093525-A1 Triamide-substituted heterobicyclic compounds APOB, MTPN, CTRB1 RAB9A 2095/4885NPC1 32/4885MEN1 1637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.