SCHEMBL4884740

SCHEMBL4884740

COc1ccc(C=CC(=O)OC(C)C)c(C(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CA12 O43570 1/20 0.46
AKR1B10 O60218 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
AKR1B1 P15121 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
JUN P05412 1/20 0.44
NFKB1 P19838 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropyl 3-(4-Isopropylphenyl)Acrylate SCHEMBL28526350 0.87 KDM4E (0.52) MAPTMEN1KMT2ACA12AKR1B10
SCHEMBL490210 0.84 THRB (0.53) MAPTALDH1A1MEN1KMT2AJUN
SCHEMBL490211 0.84 THRB (0.53) MAPTALDH1A1MEN1KMT2AJUN
SCHEMBL25211344 0.83 CA12 (0.48) MAPTCA12AKR1B10CA1CA2
SCHEMBL17429 0.83 CA12 (0.48) MAPTCA12AKR1B10CA1CA2
SCHEMBL2907690 0.80 AKR1B10 (0.44) MAPTCA12AKR1B10CA1CA2
SCHEMBL29046248 0.78 KDM4E (0.47) MAPTALDH1A1MEN1KMT2AJUN
SCHEMBL15838 0.76 CA12 (0.71) MAPTMEN1KMT2ACA12AKR1B10
SCHEMBL342878 0.76 CA12 (0.71) MAPTMEN1KMT2ACA12AKR1B10
SCHEMBL4849636 0.75 CA12 (0.49) MAPTALDH1A1MEN1KMT2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118369084-A Composition for stabilizing active ingredients 莱雅公司 2024-07-19 CN disclosed
CN-114786782-B Stable composition comprising cinnamic acid derivatives in combination with specific ingredients 莱雅公司 2024-06-25 CN disclosed
CN-114760982-B Composition comprising a cationic polysaccharide and an anionic antioxidant 莱雅公司 2024-05-31 CN disclosed
WO-2023245462-A1 STABILIZED COMPOSITION COMPRISING THIOPYRIDINONE COMPOUND L'OREAL (FR) 2023-12-28 WO disclosed
WO-2023245459-A1 ANTI-OXIDIZING COMPOSITION COMPRISING A THIOPYRIDINONE COMPOUND L'OREAL (FR) 2023-12-28 WO disclosed
WO-2023249122-A1 STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME L'OREAL (FR) 2023-12-28 WO disclosed
WO-2023249912-A1 COSMETIC COMPOSITION COMPRISING HYDROPHILIC ANTIOXIDANTS AND THIOPYRIDINONE COMPOUNDS L'OREAL (FR) 2023-12-28 WO disclosed
WO-2023102894-A1 COMPOSITION FOR STABILIZING ACTIVE INGREDIENTS L'OREAL (FR) 2023-06-15 WO disclosed
US-20230048170-A1 COMPOSITION INCLUDING CATIONIC POLYSACCHARIDE AND ANIONIC ANTIOXIDANT L'OREAL (FR) 2023-02-16 US disclosed
US-20230021127-A1 STABLE COMPOSITION COMPRISING COMBINATION OF CINNAMIC ACID DERIVATIVES WITH SPECIFIC INGREDIENTS L'OREAL (FR) 2023-01-19 US disclosed
WO-2012086843-A1 POLYSILOXANE-HYDROCARBYLENE AMINOHYDROCARBYLENE MULTIBLOCK COPOLYMER AND METHOD FOR PRODUCING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2012-06-28 WO disclosed
US-20080248121-A1 MULTIPLE EMULSION CONTAINING A TENSIONING AGENT L'OREAL (FR) 2008-10-09 US disclosed
US-20070009453-A1 Photoprotective compositions comprising an aqueous phase and a low melting point apolar wax L'OREAL (FR) 2007-01-11 US disclosed
US-7045120-B2 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers L'OREAL (FR) 2006-05-16 US disclosed
US-6955803-B2 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers L'OREAL (FR) 2005-10-18 US disclosed
US-6875426-B2 Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent L'OREAL (FR) 2005-04-05 US disclosed
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL S.A. (FR) 2004-04-15 US disclosed
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL, S.A. (FR) 2004-04-01 US disclosed
US-20030228268-A1 Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent SOCIETE L'OREAL S.A. (FR) 2003-12-11 US disclosed
US-20030215476-A1 Multiple emulsion containing a tensioning agent L'OREAL (FR) 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, PCNA, DSG1 MAPT 2862/4885ALDH1A1 1614/4885MEN1 4030/4885
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, DSG1, PCNA MAPT 660/4885ALDH1A1 2367/4885MEN1 1959/4885
US-20030228268-A1 Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent TYR, TES, TERT MAPT 1211/4885ALDH1A1 868/4885MEN1 1731/4885
US-20230021127-A1 STABLE COMPOSITION COMPRISING COMBINATION OF CINNAMIC ACID DERIVATIVES WITH SPECIFIC INGREDIENTS NQO1, ALOX5, LPO MAPT 2203/4885ALDH1A1 75/4885MEN1 2780/4885
US-20230048170-A1 COMPOSITION INCLUDING CATIONIC POLYSACCHARIDE AND ANIONIC ANTIOXIDANT GPX4, LPO, SOD3 MAPT 4039/4885ALDH1A1 1853/4885MEN1 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.