Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447 | 0.80 | MAOA (0.39) | MAOAMAPT | |
| SCHEMBL3679233 | 0.78 | NOTUM (0.47) | NOTUML3MBTL1HPGDKDM4EHTT | |
| SCHEMBL15657033 | 0.78 | NOTUM (0.47) | NOTUML3MBTL1KDM4EHTTALDH1A1 | |
| SCHEMBL8513179 | 0.71 | MGLL (0.37) | ALDH1A1MAPTPTGS2 | |
| SCHEMBL2819853 | 0.71 | RAB9A (0.43) | GAAKDM4EHTTALDH1A1ALKBH2 | |
| SCHEMBL2818806 | 0.71 | KCNMA1 (0.43) | L3MBTL1GAAHPGDKDM4EHTT | |
| SCHEMBL8513208 | 0.71 | MGLL (0.37) | — | |
| SCHEMBL430176 | 0.65 | GAA (0.42) | NOTUMP2RX7L3MBTL1MAOAGAA | |
| SCHEMBL11354357 | 0.64 | LTA4H (0.32) | HTT | |
| SCHEMBL17080299 | 0.64 | NOTUM (0.39) | NOTUMP2RX7L3MBTL1MAOAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 960 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217457-A | 4-amino-1H-pyrrole compound, preparation method and application | 中国药科大学 | 2023-06-06 | — | — | CN | claimed |
| CN-116082253-A | 1-N-substituted 1,2, 3-triazole-4-carboxamide derivative and preparation method thereof | 浙大城市学院 | 2023-05-09 | — | — | CN | claimed |
| US-20210024489-A1 | TREATMENT AND PREVENTION OF NEUROPATHIC PAIN WITH P2Y14 ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2021-01-28 | — | — | US | claimed |
| CN-107531690-B | 4,5,6, 7-tetrahydro-1H-pyrazolo [4,3-c ] pyridin-3-amine compounds as CBP and/or EP300 inhibitors | 基因泰克公司 | 2020-11-06 | — | — | CN | claimed |
| EP-3626717-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2020-03-25 | — | — | EP | claimed |
| EP-2581365-B1 | Heterocyclic compound, organic light-emitting diode comprising the heterocyclic compound, and flat panel display device comprising the organic light-emitting diode | SAMSUNG DISPLAY CO LTD (KR) | 2019-10-16 | — | — | EP | claimed |
| US-RE47193-E1 | Selectively substituted quinoline compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-01-08 | — | — | US | claimed |
| US-20180305391-A1 | COFACTOR ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-10-25 | — | — | US | claimed |
| US-20180291263-A1 | SPIROFLUORENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES | WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2018-10-11 | — | — | US | claimed |
| US-20180294417-A1 | FLUORENE-CARBAZOLE DERIVATIVES AND PHOSPHORESCENT ORGANIC ELECTROLUMINESCENT DEVICES | WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2018-10-11 | — | — | US | claimed |
| WO-2006013195-A1 | 5-SUBSTITUTED 1H-PYRROLO[3,2-B]PYRIDINES | ALTANA PHARMA AG (DE) | 2006-02-09 | — | — | WO | claimed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | claimed |
| WO-2005105864-A1 | HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-11-10 | — | — | WO | claimed |
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| US-20040171881-A1 | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | PHARMACIA & UPJOHN COMPANY | 2004-09-02 | — | — | US | claimed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| US-5269815-A | Process for the fluorescent whitening of hydrophobic textile material with disperse fluorescent whitening agents from super-critical carbon dioxide | CIBA-GEIGY CORPORATION (US) | 1993-12-14 | — | — | US | claimed |
| EP-0543779-A1 | Process for optical bleaching of hydrophobic textile material with disperse optical brightness in supercritical CO2 | CIBA-GEIGY AG (CH) | 1993-05-26 | — | — | EP | claimed |
| US-5185027-A | Salicylaldehyde derivatives and salicyclic acid derivatives and their sulfur analogs, and their use as herbicides and bioregulators | BASF AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | claimed |
| US-5085686-A | Plant growth regulator | BASF AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305391-A1 | COFACTOR ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | NNMT, BHMT, MAT2B | NOTUM 1355/4885P2RX7 4669/4885L3MBTL1 178/4885 |
| US-20180294417-A1 | FLUORENE-CARBAZOLE DERIVATIVES AND PHOSPHORESCENT ORGANIC ELECTROLUMINESCENT DEVICES | FOXO3, TEC, GDI2 | NOTUM 3978/4885P2RX7 713/4885L3MBTL1 2979/4885 |
| US-20180291263-A1 | SPIROFLUORENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES | SLCO4C1, GFPT1, TRPA1 | NOTUM 4679/4885P2RX7 1289/4885L3MBTL1 4233/4885 |
| US-20040171881-A1 | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | BACE1, BACE2, PSEN1 | NOTUM 1213/4885P2RX7 2420/4885L3MBTL1 2946/4885 |
| US-20210024489-A1 | TREATMENT AND PREVENTION OF NEUROPATHIC PAIN WITH P2Y14 ANTAGONISTS | P2RY14, P2RY4, P2RY13 | NOTUM 3292/4885P2RX7 17/4885L3MBTL1 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.