SCHEMBL498610

SCHEMBL498610

Cc1ccc(/C=C/c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)o1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRAF P15056 1/20 0.47
ALDH1A1 P00352 12/20 0.41
MAPT P10636 10/20 0.41
KDM4E B2RXH2 9/20 0.41
SMN1; SMN2 Q16637 8/20 0.41
RAB9A P51151 7/20 0.41
KMT2A Q03164 6/20 0.41
MEN1 O00255 5/20 0.41
NPC1 O15118 5/20 0.41
HTT P42858 3/20 0.41
LMNA P02545 3/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PKM P14618 3/20 0.36
HPGD P15428 5/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
ALOX5 P09917 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498611 1.00 BRAF (0.47) BRAFALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL25422554 1.00 BRAF (0.47) BRAFALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL19320476 0.92 BRAF (0.44) BRAFALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL30724511 0.91 BRAF (0.40) BRAFALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL13883530 0.86 BRAF (0.40) BRAFALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL17122503 0.85 BRAF (0.42) BRAFALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL13742201 0.85 BRAF (0.41) BRAFALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL5188282 0.85 BRAF (0.41) BRAFALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL4531763 0.85 BRAF (0.43) BRAFALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL499088 0.80 CYP1A2 (0.36) BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1000 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240168374-A1 PHOTORESIST COMPOSITION TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2024-05-23 US claimed
WO-2023101104-A1 PHOTOCURABLE INK COMPOSITION AND OPTICAL PRINTING METHOD USING SAME 울산과학기술원 2023-06-08 WO claimed
US-9244354-B2 Method for producing thick film photoresist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2016-01-26 US claimed
WO-2026100726-A1 DECORATIVE FILM, ELECTRONIC MEMBER, AND TOUCH PAD JSR株式会社 2026-05-15 WO disclosed
US-20260117026-A1 DIELECTRIC MATERIALS BASED ON HETEROAROMATIC-EXTENDED BISMALEIMIDES MERCK PATENT GMBH (DE) 2026-04-30 US disclosed
US-20260098128-A1 CURABLE BRANCHED ORGANOPOLYSILOXANE, HIGH ENERGY RAY-CURABLE COMPOSITION CONTAINING SAME, AND USE THEREOF DOW TORAY CO LTD (JP) 2026-04-09 US disclosed
US-20260085194-A1 OPTICAL PRODUCT TOKYO OHKA KOGYO CO LTD (JP) 2026-03-26 US disclosed
US-12583973-B2 Polyimide-based polymer, positive photosensitive resin composition, negative photosensitive resin composition, patterning method, method for forming cured film, interlayer insulating film, surface protective film, and electronic component SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-24 US disclosed
US-12583975-B2 UV-curable organopolysiloxane composition and use thereof DOW TORAY CO., LTD. (JP) 2026-03-24 US disclosed
US-20260049187-A1 CO-MODIFIED BRANCHED ORGANOPOLYSILOXANE, HIGH ENERGY RAY-CURABLE COMPOSITION CONTAINING SAME, AND USE OF SAME DOW TORAY CO LTD (JP) 2026-02-19 US disclosed
US-12552888-B2 Curable resin composition and display device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-02-17 US disclosed
EP-1163553-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS Ciba SC Holding AG (CH) 2001-12-19 EP disclosed
US-6268108-B1 MIXTURE OF COMPOUND FORMING ACID UPON EXPOSURE OF ACTINIC RADIATION, COMPOUND CAPABLE OF CROSSLINKING, DYE AND SOLVENT TOKYO OHKA KOGYO CO., LTD. (JP) 2001-07-31 US disclosed
US-20010004511-A1 Pigment-dispersion photo-sensitive coating solution SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2001-06-21 US disclosed
EP-1103856-A1 Positive resist composition & process for forming resist pattern using same Central Glass Company, Limited (JP) 2001-05-30 EP disclosed
US-6225476-B1 ACRYLIC ESTER COMPOUND HAVING ALKOXYCARBONYL GROUP OR GROUP DERIVED FROM MOLECULE OF LACTONE COMPOUND BY REMOVING HYDROGEN ATOM BONDED TO CARBON ATOM; MONOMER OF FILM-FORMING RESIN TOKYO OHKA KOGYO CO., LTD. (JP) 2001-05-01 US disclosed
US-6190833-B1 (A) A PHENOL RESIN, (B) AN AMINO RESIN, (C) A COMPOUND HAVING TWO OR MORE CROSSLINKING GROUPS IN A MOLECULE, AND (D) A HALOMETHYL-1,3,5-TRIAZINE COMPOUND. JSR CORPORATION (JP) 2001-02-20 US disclosed
WO-2000052530-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-08 WO disclosed
US-6087063-A Positive-working photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 2000-07-11 US disclosed
US-5368783-A Novolak resin or polyhydroxystyrene resin, alkoxymethylated amino resin and triazine TOKYO OHKA KOGYO CO., LTD. (JP) 1994-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085194-A1 OPTICAL PRODUCT PFN1, CFL1, C9 BRAF 3071/4885ALDH1A1 2131/4885MAPT 444/4885
US-12552888-B2 Curable resin composition and display device RAD51, LPO, FTO BRAF 2229/4885ALDH1A1 1278/4885MAPT 1289/4885
US-20260049187-A1 CO-MODIFIED BRANCHED ORGANOPOLYSILOXANE, HIGH ENERGY RAY-CURABLE COMPOSITION CONTAINING SAME, AND USE OF SAME MSR1, HAO2, COL2A1 BRAF 4738/4885ALDH1A1 1755/4885MAPT 3578/4885
US-20260098128-A1 CURABLE BRANCHED ORGANOPOLYSILOXANE, HIGH ENERGY RAY-CURABLE COMPOSITION CONTAINING SAME, AND USE THEREOF COL2A1, COL1A1, SEM1 BRAF 3477/4885ALDH1A1 1729/4885MAPT 3200/4885
US-20260117026-A1 DIELECTRIC MATERIALS BASED ON HETEROAROMATIC-EXTENDED BISMALEIMIDES KCNE1, GLRB, PBRM1 BRAF 2637/4885ALDH1A1 1854/4885MAPT 2622/4885
US-12583973-B2 Polyimide-based polymer, positive photosensitive resin composition, negative photosensitive resin composition, patterning method, method for forming cured film, interlayer insulating film, surface protective film, and electronic component PRDM9, ARCN1, PUF60 BRAF 1379/4885ALDH1A1 3281/4885MAPT 784/4885
US-12583975-B2 UV-curable organopolysiloxane composition and use thereof F12, FUCA1, XPA BRAF 2396/4885ALDH1A1 1322/4885MAPT 4363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.