SCHEMBL5358510

SCHEMBL5358510

COC(CC(C)C)c1ccc(C=CC(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.59
MAPK1 P28482 2/20 0.59
THRB P10828 1/20 0.51
ATM Q13315 1/20 0.51
CA12 O43570 3/20 0.45
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CA4 P22748 3/20 0.45
CA6 P23280 3/20 0.45
CA5A P35218 3/20 0.45
CA7 P43166 3/20 0.45
CA9 Q16790 3/20 0.45
CA14 Q9ULX7 3/20 0.45
CA5B Q9Y2D0 3/20 0.45
HCAR2 Q8TDS4 2/20 0.45
CA3 P07451 2/20 0.45
PKM P14618 2/20 0.45
AKR1B10 O60218 1/20 0.45
ESR1 P03372 1/20 0.45
TYR P14679 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21462398 1.00 KDM4E (0.59) KDM4EMAPK1THRBATMCA12
SCHEMBL16617837 0.80 KDM4E (0.53) KDM4EMAPK1THRBATMCA12
SCHEMBL83535 0.78 KDM4E (0.50) KDM4EMAPK1THRBATMCA12
SCHEMBL3858925 0.78 KDM4E (0.66) KDM4EMAPK1THRBATMCA12
SCHEMBL3857561 0.78 KDM4E (0.66) KDM4EMAPK1THRBATMCA12
SCHEMBL1711780 0.76 KDM4E (1.00) KDM4EMAPK1THRBATMCA12
SCHEMBL819055 0.76 KDM4E (1.00) KDM4EMAPK1THRBATMCA12
SCHEMBL11683046 0.74 KDM4E (0.76) KDM4EMAPK1THRBATMCA12
SCHEMBL13349804 0.73 KDM4E (0.55) KDM4EMAPK1THRBATMCA12
SCHEMBL18713537 0.73 KDM4E (0.69) KDM4EMAPK1THRBATMCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107625660-B Transparent sunscreen oil gel and preparation method thereof 广州环亚化妆品科技有限公司 2021-04-02 CN claimed
EP-4358932-A1 THICKENING COMPOSITION FOR THICKENING POLAR OR NON-POLAR OILS Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2024-05-01 EP disclosed
EP-4358933-A1 COPOLYMER THICKENING COMPOSITION COMPRISING AT LEAST ONE OIL AND AT LEAST ONE POLY(ITACONATE) FOR THICKENING POLAR OR APOLAR OILS Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2024-05-01 EP disclosed
EP-4349418-A2 TOPICALLY ADMINISTRABLE HELICHRYSUM STOECHAS PLANT DEDIFFERENTIATED CELL LYSATE (LY) FOR REMOVING OR REDUCING SKIN INFLAMMATION Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2024-04-10 EP disclosed
EP-4106784-B1 TOPICALLY ADMINISTRABLE LYSATE (LY) OF DEDIFFERENTIATED CELLS OF THE PLANT HELICHRYSUM STOECHAS FOR ELIMINATING OR REDUCING INFLAMMATION OF THE SKIN SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2024-04-03 EP disclosed
EP-4331686-A2 TEMPERATURE-STABLE ALKANE AND ESTER COMPOSITIONS, THEIR USE AS EMOLLIENT AGENTS, AND EMULSIONS COMPRISING THEM Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2024-03-06 EP disclosed
EP-4073170-B1 PROCESS FOR PREPARING AN INVERSE LATEX FOR COSMETIC COMPOSITION COMBINING A PARTICULAR SEQUESTERING AGENT AND A POLYELECTROLYTE COMPRISING A WEAK ACID FUNCTION SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2024-02-21 EP disclosed
US-20240026078-A1 Polymer taking the form of a pulverulent solid and having properties for thickening polar media SOCIETE D'EXPLOITATION DE PRO­DUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2024-01-25 US disclosed
EP-4106720-B1 TOPICALLY ADMINISTRABLE LYSATE OF DEDIFFERENTIATED CELLS OF THE PLANT HELICHRYSUM STOECHAS FOR MOISTURIZING SKIN SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2023-12-27 EP disclosed
EP-4274859-A1 COMPOSITION COMPRISING POLYMERS OF NATURAL ORIGIN AND HAVING PROPERTIES FOR THICKENING POLAR MEDIA Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2023-11-15 EP disclosed
US-20190336435-A1 METHOD FOR OBTAINING A DIGLYCOSIDE-ENRICHED ARMERIA MARITIMA EXTRACT, AND USE THEREOF IN COSMETICS Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2019-11-07 US disclosed
EP-3554462-A1 METHOD FOR IMPROVING THE SENSORIAL PROPERTIES OF OIL-IN-WATER EMULSIONS Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2019-10-23 EP disclosed
US-10052275-B2 Surfactant-free self-reversible reverse latex, and use of same as a thickening agent in a cosmetic composition SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2018-08-21 US disclosed
US-20180116946-A1 NOVEL COSMETIC EMULSIONS PROVIDED IN FOAM FORM, METHOD FOR OBTAINING SAME AND COSMETIC USE THEREOF SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2018-05-03 US disclosed
US-20170312205-A1 USE OF ESTERS OF N-ACYLATED DERIVATIVES OF AMINO ACIDS AND POLYOLS AS AN ANTI-AGEING AGENT FOR HUMAN SKIN SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2017-11-02 US disclosed
US-20170304177-A1 USE OF ISOSORBIDE ESTER AND N-ACYLATED AMINO ACID DERIVATIVES AS ANTI-AGEING AGENT FOR THE HUMAN SKIN SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2017-10-26 US disclosed
US-20160015609-A1 NOVEL WATER-IN-OIL EMULSIONS WITH A HIGH CONTENT OF AQUEOUS PHASE AND OF LIQUID CONSISTENCY, WHICH ARE STABLE ON STORAGE SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2016-01-21 US disclosed
US-20150098915-A1 NOVEL SURFACTANT-FREE SELF-REVERSIBLE REVERSE LATEX, AND USE OF SAME AS A THICKENING AGENT IN A COSMETIC COMPOSITION SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2015-04-09 US disclosed
US-7226580-B2 Topical compositions with an oily outer phase and process for their preparation SEPPIC (FR) 2007-06-05 US disclosed
US-20040071642-A1 Novel topical compositions with an oily outer phase and process for their preparation SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES-SEPPIC 2004-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040071642-A1 Novel topical compositions with an oily outer phase and process for their preparation CUTA, TYR, ERCC5 KDM4E 1427/4885MAPK1 4086/4885THRB 4802/4885
US-20160015609-A1 NOVEL WATER-IN-OIL EMULSIONS WITH A HIGH CONTENT OF AQUEOUS PHASE AND OF LIQUID CONSISTENCY, WHICH ARE STABLE ON STORAGE DEGS1, PHOSPHO1, DAGLA KDM4E 3846/4885MAPK1 1479/4885THRB 4669/4885
US-20150098915-A1 NOVEL SURFACTANT-FREE SELF-REVERSIBLE REVERSE LATEX, AND USE OF SAME AS A THICKENING AGENT IN A COSMETIC COMPOSITION DEGS1, SRM, SMURF1 KDM4E 1453/4885MAPK1 3759/4885THRB 4325/4885
US-20170304177-A1 USE OF ISOSORBIDE ESTER AND N-ACYLATED AMINO ACID DERIVATIVES AS ANTI-AGEING AGENT FOR THE HUMAN SKIN ARG2, ARGLU1, ASS1 KDM4E 2875/4885MAPK1 2483/4885THRB 2266/4885
US-20240026078-A1 Polymer taking the form of a pulverulent solid and having properties for thickening polar media PGAM1, GLUL, SGTA KDM4E 4089/4885MAPK1 3239/4885THRB 4654/4885
US-10052275-B2 Surfactant-free self-reversible reverse latex, and use of same as a thickening agent in a cosmetic composition DEGS1, SMURF1, SRM KDM4E 1532/4885MAPK1 3421/4885THRB 4136/4885
US-20180116946-A1 NOVEL COSMETIC EMULSIONS PROVIDED IN FOAM FORM, METHOD FOR OBTAINING SAME AND COSMETIC USE THEREOF CUTA, DAGLA, DEGS1 KDM4E 2274/4885MAPK1 1850/4885THRB 4809/4885
US-20170312205-A1 USE OF ESTERS OF N-ACYLATED DERIVATIVES OF AMINO ACIDS AND POLYOLS AS AN ANTI-AGEING AGENT FOR HUMAN SKIN LPO, ARG2, CUTA KDM4E 1454/4885MAPK1 2406/4885THRB 2232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.