Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707618 | 0.79 | — | — | |
| SCHEMBL15302067 | 0.70 | DAO (0.32) | — | |
| SCHEMBL8858240 | 0.70 | LMNA (0.31) | — | |
| SCHEMBL154612 | 0.69 | CALM1 (0.32) | — | |
| SCHEMBL2412791 | 0.69 | TSHR (0.41) | — | |
| SCHEMBL7640557 | 0.69 | CALM1 (0.32) | — | |
| SCHEMBL9355285 | 0.68 | MAPT (0.37) | — | |
| SCHEMBL9355276 | 0.68 | MAPT (0.37) | — | |
| SCHEMBL10864226 | 0.68 | TDP1 (0.54) | — | |
| SCHEMBL704630 | 0.68 | CALM1 (0.35) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4628483-A1 | DIHYDROPHTHALAZINE-CONTAINING COMPOUND | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2025-10-08 | — | — | EP | disclosed |
| EP-4615847-A1 | SMALL MOLECULE INHIBITORS OF KRAS PROTEINS | Merck Sharp & Dohme LLC (US) | 2025-09-17 | — | — | EP | disclosed |
| EP-3762377-B1 | PYRIDINONE- AND PYRIDAZINONE-BASED COMPOUNDS AND MEDICAL USES THEREOF | UNIV CORNELL (US) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024114635-A1 | DIHYDROPHTHALAZINE-CONTAINING COMPOUND | 正大天晴药业集团股份有限公司 | 2024-06-06 | — | — | WO | disclosed |
| WO-2024103010-A1 | SMALL MOLECULE INHIBITORS OF KRAS PROTEINS | MERCK SHARP & DOHME LLC (US) | 2024-05-16 | — | — | WO | disclosed |
| US-11964960-B2 | Pyridinone- and pyridazinone-based compounds and uses thereof | CORNELL UNIVERSITY (US) | 2024-04-23 | — | — | US | disclosed |
| WO-2023169547-A1 | DNA POLYMERASE θ INHIBITOR AND USE THEREOF | 四川海思科制药有限公司 | 2023-09-14 | — | — | WO | disclosed |
| WO-2021122645-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-06-24 | — | — | WO | disclosed |
| EP-3762377-A1 | PYRIDINONE- AND PYRIDAZINONE-BASED COMPOUNDS AND MEDICAL USES THEREOF | Cook, Timothy, H. (US) | 2021-01-13 | — | — | EP | disclosed |
| US-20200407339-A1 | PYRIDINONE- AND PYRIDAZINONE-BASED COMPOUNDS AND USES THEREOF | TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE | 2020-12-31 | — | — | US | disclosed |
| US-7030137-B2 | Substituted thiophenes with antibacterial activity | REPLIDYNE, INC. (US) | 2006-04-18 | — | — | US | disclosed |
| US-20060014748-A1 | 2-NH-heteroarylimidazoles with antibacterial activity | BERGE JOHN | 2006-01-19 | — | — | US | disclosed |
| EP-1581220-A2 | 2-NH-HETEROARYLIMIDAZOLES WITH ANTIBACTERIAL ACTIVITY | Replidyne, Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| US-6943175-B2 | 2-NH-heteroarylimidazoles with antibacterial activity | REPLIDYNE, INC. (US) | 2005-09-13 | — | — | US | disclosed |
| US-20050176706-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-08-11 | — | — | US | disclosed |
| WO-2005030213-A1 | 1,1,1-TRIFLUORO-4-PHENYL-4-METHYL-2-(1H-PYRROLO | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050009833-A1 | Substituted thiophenes with antibacterial activity | REPLIDYNE, INC. | 2005-01-13 | — | — | US | disclosed |
| US-20040224981-A1 | Antibacterial methods and compositions | REPLIDYNE, INC. | 2004-11-11 | — | — | US | disclosed |
| US-20040147548-A1 | 2-NH-heteroarylimidazoles with antibacterial activity | REPLIDYNE, INC. | 2004-07-29 | — | — | US | disclosed |
| WO-2004052288-A2 | 2-NH-HETEROARYLIMIDAZOLES WITH ANTIBACTERIAL ACTIVITY | REPLIDYNE, INC. (US) | 2004-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176706-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof | NR3C1, NR3C2, MC2R | MAOA 3497/4885MAOB 2970/4885 |
| US-20040147548-A1 | 2-NH-heteroarylimidazoles with antibacterial activity | NSUN3, TRMT1, NOP2 | MAOA 2188/4885MAOB 1969/4885 |
| US-20040224981-A1 | Antibacterial methods and compositions | AARS1, NOP2, NSUN3 | MAOA 2810/4885MAOB 3153/4885 |
| US-20200407339-A1 | PYRIDINONE- AND PYRIDAZINONE-BASED COMPOUNDS AND USES THEREOF | PTGER1, LOXL1, COL1A1 | MAOA 1127/4885MAOB 552/4885 |
| US-20050009833-A1 | Substituted thiophenes with antibacterial activity | TST, MTR, NSUN3 | MAOA 1758/4885MAOB 1013/4885 |
| US-20060014748-A1 | 2-NH-heteroarylimidazoles with antibacterial activity | TRMT1, NSUN3, NOP2 | MAOA 2100/4885MAOB 1744/4885 |
| US-11964960-B2 | Pyridinone- and pyridazinone-based compounds and uses thereof | PTGER1, LOXL1, COL1A1 | MAOA 1127/4885MAOB 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.