Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.56 |
| ▸ | PPARG | P37231 | 5/20 | 0.54 |
| ▸ | PPARA | Q07869 | 5/20 | 0.54 |
| ▸ | TERT | O14746 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | TOP1 | P11387 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751614 | 1.00 | PTPN1 (0.56) | PTPN1PPARGPPARATERTPPARD | |
| SCHEMBL5498298 | 1.00 | PTPN1 (0.56) | PTPN1PPARGPPARATERTPPARD | |
| SCHEMBL3345156 | 1.00 | PTPN1 (0.56) | PTPN1PPARGPPARATERTPPARD | |
| SCHEMBL8083753 | 1.00 | PTPN1 (0.56) | PTPN1PPARGPPARATERTPPARD | |
| SCHEMBL4751612 | 1.00 | PTPN1 (0.56) | PTPN1PPARGPPARATERTPPARD | |
| SCHEMBL8083757 | 1.00 | PTPN1 (0.56) | PTPN1PPARGPPARATERTPPARD | |
| SCHEMBL3345152 | 1.00 | PTPN1 (0.56) | PTPN1PPARGPPARATERTPPARD | |
| SCHEMBL15515132 | 0.98 | PTPN1 (0.53) | PTPN1PPARGPPARATERTPPARD | |
| SCHEMBL15515133 | 0.98 | PTPN1 (0.53) | PTPN1PPARGPPARATERTPPARD | |
| SCHEMBL8075370 | 0.87 | FASN (0.59) | PTPN1PPARGPPARATERTPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014039940-A1 | CELLS AND METHODS FOR THE PRODUCTION OF RHAMNOLIPIDS | LOGOS TECHNOLOGIES LLC (US) | 2014-03-13 | — | — | WO | claimed |
| US-9523673-B2 | Methods for diagnosing and identifying modulators of membrane potentials in bipolar disorder and attention deficit hyperactivity disorder | PSYCHNOSTICS, LLC (US) | 2016-12-20 | — | — | US | disclosed |
| US-9029342-B2 | Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-05-12 | — | — | US | disclosed |
| US-20140248652-A1 | METHODS FOR DIAGNOSING AND IDENTIFYING MODULATORS OF MEMBRANE POTENTIALS IN BIPOLAR DISORDER AND ATTENTION DEFICIT HYPERACTIVITY DISORDER | PSYCHNOSTICS, LLC (US) | 2014-09-04 | — | — | US | disclosed |
| US-20140128588-A1 | COMPOSITIONS OF MATTER THAT REDUCE PAIN, SHOCK, AND INFLAMMATION BY BLOCKING LINOLEIC ACID METABOLITES AND USES THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-05-08 | — | — | US | disclosed |
| WO-2014039940-A1 | CELLS AND METHODS FOR THE PRODUCTION OF RHAMNOLIPIDS | LOGOS TECHNOLOGIES LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| US-20120195862-A1 | BIOMECHANICAL INDUCTION OF HEMATOPOIESIS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2012-08-02 | — | — | US | disclosed |
| US-20110065801-A1 | ENZYMATIC SYNTHESIS OF SPHINGOLIPIDS | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-03-17 | — | — | US | disclosed |
| US-20070066572-A1 | Neuroprotection by positively-charged nitroxides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-03-22 | — | — | US | disclosed |
| US-20060165630-A1 | Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin | L'OREAL (FR) | 2006-07-27 | — | — | US | disclosed |
| US-20060111407-A1 | Association between a heterocyclic compound stimulating lipid and carbohydrate metabolisms and an antioxidant agent for treating obesity | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-05-25 | — | — | US | disclosed |
| US-20060079488-A1 | Methods of treating and preventing bone loss | ALLARD JOHN D | 2006-04-13 | — | — | US | disclosed |
| US-20060014820-A1 | Lipid-amino acid conjugates and methods of use | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-01-19 | — | — | US | disclosed |
| US-20060002911-A1 | Association between a ppar ligand and an antioxidant agent and use thereof for treating obesity | LES LABORATORIES SERVIER (FR) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014820-A1 | Lipid-amino acid conjugates and methods of use | SLC27A2, SLC27A1, FABP2 | PTPN1 2487/4885PPARG 160/4885PPARA 224/4885 |
| US-20060079488-A1 | Methods of treating and preventing bone loss | ALOX5, SOST, ALOX15B | PTPN1 3739/4885PPARG 616/4885PPARA 410/4885 |
| US-20070066572-A1 | Neuroprotection by positively-charged nitroxides | NLN, HSPE1, AIFM1 | PTPN1 3268/4885PPARG 1182/4885PPARA 1155/4885 |
| US-20140128588-A1 | COMPOSITIONS OF MATTER THAT REDUCE PAIN, SHOCK, AND INFLAMMATION BY BLOCKING LINOLEIC ACID METABOLITES AND USES THEREOF | FABP1, HSPBP1, LTA | PTPN1 4765/4885PPARG 312/4885PPARA 39/4885 |
| US-20110065801-A1 | ENZYMATIC SYNTHESIS OF SPHINGOLIPIDS | ASAH1, SMPD1, ASAH2 | PTPN1 3345/4885PPARG 2483/4885PPARA 2717/4885 |
| US-20060111407-A1 | Association between a heterocyclic compound stimulating lipid and carbohydrate metabolisms and an antioxidant agent for treating obesity | PC, GPR119, LIPC | PTPN1 3202/4885PPARG 19/4885PPARA 44/4885 |
| US-20060165630-A1 | Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin | CUTA, SCD5, SCD | PTPN1 2278/4885PPARG 121/4885PPARA 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.