Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557352 | 1.00 | NR4A1 (0.46) | NR4A1ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL31441383 | 1.00 | NR4A1 (0.46) | NR4A1ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL27823784 | 0.92 | CTRB1 (0.44) | NR4A1ALDH1A1HPGDHSD17B10CYP3A4 | |
| Potassium Ion SCHEMBL11528259 | 0.88 | NR4A1 (0.47) | NR4A1ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL11528709 | 0.87 | THRB (0.47) | NR4A1ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL18274827 | 0.87 | DUSP5 (0.45) | NR4A1ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL450356 | 0.85 | NR4A1 (0.39) | NR4A1ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL221346 | 0.85 | NR4A1 (0.39) | NR4A1ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL27939682 | 0.85 | DUSP5 (0.47) | NR4A1ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL30538112 | 0.85 | THRB (0.43) | NR4A1ALDH1A1HPGDHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119570478-A | Indicator replacement sensor for detecting perfluorooctane sulfonic acid, and preparation method and application thereof | 三峡环境科技有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-117758329-A | Electroplating method containing graphene | 浙江正泰电器股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-112661973-B | Preparation and structure of calixadine and pyrene sulfonate supramolecular nanoparticles and application of calixadine and pyrene sulfonate supramolecular nanoparticles in induced aggregation luminescence | 天津师范大学 | 2022-12-06 | — | — | CN | claimed |
| CN-111808078-B | Lenalidomide derivative for inhibiting IDO1 activity and preparation method and application thereof | 济南爱思医药科技有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-115015192-A | Gold nanoparticle-based sensor and detection method of glutathione and oxidation degree thereof | 扬州大学 | 2022-09-06 | — | — | CN | claimed |
| CN-114901754-A | Methods and compositions for producing graphene polyurethane foams | 普世物料公司 | 2022-08-12 | — | — | CN | claimed |
| CN-111875589-B | Indirubin derivative used in combination with polypeptide and preparation method and application thereof | 济南爱思医药科技有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-110698326-B | Synthesis method of 1-hydroxypyrene | 福建福瑞明德药业有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-113512135-A | Preparation method of oxime ester photoinitiator | 优缔贸易(上海)有限公司 | 2021-10-19 | — | — | CN | claimed |
| WO-2021077233-A1 | METHODS AND COMPOSITIONS FOR PRODUCING GRAPHENE POLYURETHANE FOAMS | UNIVERSAL MATTER INC. (CA) | 2021-04-29 | — | — | WO | claimed |
| CN-107033478-A | A kind of preparation method of graphene stable colloid | 中南民族大学 | 2017-08-11 | — | — | CN | claimed |
| CN-105536563-A | Preparation method of high-performance oxidized graphene tubular nanofiltration membrane and application thereof | UNIV BEIJING TECHNOLOGY | 2016-05-04 | — | — | CN | claimed |
| EP-2960205-A1 | Stable aqueous graphene suspension and its use in producing graphene polymer nanocomposites | Solvay SA (BE) | 2015-12-30 | — | — | EP | claimed |
| CN-103275697-B | Di-pyrene amphiphilic fluorescent probe and synthesis method and application thereof | UNIV SHAANXI NORMAL | 2014-09-17 | — | — | CN | claimed |
| CN-103275697-A | Di-pyrene amphiphilic fluorescent probe and synthesis method and application thereof | UNIV SHAANXI NORMAL | 2013-09-04 | — | — | CN | claimed |
| CN-101943919-B | Method for controlling concentration multiplying power of circulating cooling water and concentration multiplier | TIANJIN TIANYI QINGYUAN TECHNOLOGY DEV CO LTD | 2011-11-16 | — | — | CN | claimed |
| CN-201812213-U | Concentration ratio instrument for circulating cooling water system | TIANJIN TIANYI QINGYUAN SCIENCE AND TECHNOLOGY DEV CO LTD | 2011-04-27 | — | — | CN | claimed |
| CN-100544823-C | A kind of preparation method of nanometer particle carbon nanotube compound catalyst | CHANGCHUN APPLIED CHEMISTRY (CN) | 2009-09-30 | — | — | CN | claimed |
| CN-101224434-A | Preparing method of nanometer particle carbon nanotube compound catalyst | CHANGCHUN APPLIED CHEMISTRY (CN) | 2008-07-23 | — | — | CN | claimed |
| CN-101050358-A | Method for preparing dyestuff controllable doped Nano particles of silicon dioxide | UNIV JILIN (CN) | 2007-10-10 | — | — | CN | claimed |