SCHEMBL615152

SCHEMBL615152

Cc1cn(C)c(=O)n(C)c1=O

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
ALDH1A1 P00352 2/20 0.47
POLB P06746 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
TSHR P16473 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HTT P42858 1/20 0.42
GAA P10253 2/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GFER P55789 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8696410 0.78 ATAD2 (0.38) LMNAALDH1A1POLBL3MBTL1SMN1; SMN2
SCHEMBL19235507 0.76 BRD4 (0.36) LMNAALDH1A1POLBL3MBTL1TSHR
SCHEMBL14491564 0.76 BRD4 (0.36) LMNAALDH1A1POLBL3MBTL1TSHR
SCHEMBL11869254 0.76 BRPF1 (0.35) LMNAALDH1A1POLBL3MBTL1SMN1; SMN2
SCHEMBL3806347 0.76 FEN1 (0.38) LMNAALDH1A1POLBSMN1; SMN2HSD17B10
SCHEMBL23029099 0.75 BRD4 (0.35) LMNAALDH1A1POLBL3MBTL1
SCHEMBL9972888 0.75 ALDH1A1 (0.40) LMNAALDH1A1POLBL3MBTL1SMN1; SMN2
SCHEMBL12766925 0.75 LMNA (0.40) LMNAALDH1A1POLBL3MBTL1TSHR
SCHEMBL17254245 0.75 ERN1 (0.37) LMNAALDH1A1POLBTSHRSMN1; SMN2
SCHEMBL18937487 0.75 BRD4 (0.35) LMNAALDH1A1POLBL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230027396-A1 EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS COMERA LIFE SCIENCES, INC. 2023-01-26 US claimed
EP-4065166-A1 EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS Comera Life Sciences, Inc. (US) 2022-10-05 EP claimed
CN-109799313-B Nitrogen-doped carbon material nano enzyme based on nucleic acid base or derivative thereof, and preparation method and application thereof 南京大学 2021-07-27 CN claimed
WO-2021108427-A1 EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS REFORM BIOLOGICS, LLC (US) 2021-06-03 WO claimed
JP-55111420-A None JP disclosed
WO-2024071439-A1 FUSED RING COMPOUND AND PHARMACEUTICAL CONTAINING SAME 科研製薬株式会社 2024-04-04 WO disclosed
WO-2023242662-A2 POLYMERIC TANDEM DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-12-21 WO disclosed
WO-2023242661-A2 POLYMERIC TANDEM DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-12-21 WO disclosed
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US disclosed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 US disclosed
US-20230250127-A1 MODIFIED mRNA 5'-CAP ANALOGS Nanjing GeneLeap Biotechnology Co., Ltd. (CN) 2023-08-10 US disclosed
WO-2023150592-A2 N3-SUBSTITUTED URACIL COMPOUNDS AS TRPA1 INHIBITORS D.E. SHAW RESEARCH, LLC (US) 2023-08-10 WO disclosed
US-20070025933-A1 Photoprotector and/or photoimmunoprotector compositions of the skin and their uses INDUSTRIAL FARMACEUTICA CANTABRIA, S.A. (ES) 2007-02-01 US disclosed
WO-2005094773-A1 PHOTOPROTECTIVE AND/OR PHOTOIMMUNOPROTECTIVE COMPOSITIONS FOR THE SKIN AND USES THEREOF INDUSTRIAL FARMACEUTICA CANTABRIA, S.A. (ES) 2005-10-13 WO disclosed
US-5874477-A ADMINISTERING AN AMINOTETRALIN, A PHENYL DIOXIN, A AN ERGOLINE, AN INDOLE DERIVATIVE OR AN ALKYLPIPERIDINE, PRECURSORS OF WHICH ARE FRUIT PEELINGS; DISPLACEMENT OF LIGANDS ON SUBTYPE 5HT1A OR 5HT2/5HT1C; REDUCE SYMPTOMS THE UNIVERSITY OF HAWAII (US) 1999-02-23 US disclosed
WO-1996004898-A1 A METHOD OF TREATMENT FOR MALARIA MCCONNELL BRUCE (US) 1996-02-22 WO disclosed
JP-S55111420-A ANTITUMORIGENIC AGENT ONO PHARMACEUT CO LTD 1980-08-28 JP disclosed
US-4210651-A Thiaprostaglandins MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1980-07-01 US disclosed
US-4171429-A Pyrimidine to pyrimidine transformation process RESEARCH CORPORATION (US) 1979-10-16 US disclosed
US-4080458-A HYPOTENSIVE AGENTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070025933-A1 Photoprotector and/or photoimmunoprotector compositions of the skin and their uses ME1, ME2, SI LMNA 3635/4885ALDH1A1 2765/4885POLB 350/4885
US-20230250127-A1 MODIFIED mRNA 5'-CAP ANALOGS RNGTT, RNMT, NSUN2 LMNA 1771/4885ALDH1A1 3421/4885POLB 534/4885
US-11771738-B2 Endoparasitic depsipeptides VIP, PREP, VIPR1 LMNA 2449/4885ALDH1A1 2109/4885POLB 4515/4885
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION POLRMT, DCLRE1B, RNGTT LMNA 2479/4885ALDH1A1 3318/4885POLB 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.