SCHEMBL649360

SCHEMBL649360

O=P(c1ccc(-c2ccc3cccnc3n2)cc1)(c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 1/20 0.44
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SUCNR1 Q9BXA5 7/20 0.37
ALDH1A1 P00352 2/20 0.35
CYP3A4 P08684 1/20 0.35
MIF P14174 1/20 0.34
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TOP1 P11387 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444861 1.00 KDM4E (0.44) KDM4ELMNAPOLBMEN1KMT2A
SCHEMBL11962384 0.86 KDM4E (0.43) KDM4ELMNAPOLBMEN1KMT2A
SCHEMBL17451977 0.82 TOP1 (0.44) KDM4ELMNAPOLBCYP3A4MAPT
SCHEMBL27779266 0.80 KDM4E (0.46) KDM4ELMNAPOLBMEN1KMT2A
SCHEMBL15581278 0.79 NPC1 (0.49) KDM4ELMNAPOLBMEN1KMT2A
SCHEMBL17452053 0.78 KDM4E (0.50) KDM4ELMNAPOLBALDH1A1CYP3A4
SCHEMBL14339264 0.78 KDM4E (0.45) KDM4ELMNAPOLBALDH1A1CYP3A4
SCHEMBL17451948 0.77 TOP1 (0.46) KDM4ELMNAPOLBMEN1KMT2A
SCHEMBL27779267 0.75 SUCNR1 (0.37) KDM4ELMNAMEN1KMT2ASUCNR1
SCHEMBL17451970 0.75 KDM4E (0.41) KDM4ELMNAPOLBALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260059938-A1 ORGANIC EL ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE TORAY INDUSTRIES, INC. (JP) 2026-02-26 US disclosed
EP-4663642-A1 POLYCYCLIC AROMATIC COMPOUND Kyoto University (JP) 2025-12-17 EP disclosed
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
EP-4635960-A1 POLYCYCLIC AROMATIC COMPOUND Kyoto University (JP) 2025-10-22 EP disclosed
US-20250169275-A1 ORGANIC EL ELEMENT MATERIAL, ORGANIC EL ELEMENT, DISPLAY DEVICE AND ILLUMINATION DEVICE TORAY INDUSTRIES, INC. (JP) 2025-05-22 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-12185625-B2 Organic electroluminescence element, display device, and lighting device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-12-31 US disclosed
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-10-31 US disclosed
EP-3960744-B1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUND (JP) 2024-08-21 EP disclosed
WO-2024166913-A1 POLYCYCLIC AROMATIC COMPOUND 国立大学法人京都大学 2024-08-15 WO disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2009-03-12 US disclosed
EP-2028249-A1 MATERIAL FOR LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING DEVICE Toray Industries, Inc. (JP) 2009-02-25 EP disclosed
EP-1942171-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed
EP-1852486-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2007-11-07 EP disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed
EP-1748045-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2007-01-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC KDM4E 518/4885LMNA 3046/4885POLB 2360/4885
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 KDM4E 1083/4885LMNA 1043/4885POLB 2252/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 KDM4E 1365/4885LMNA 2487/4885POLB 1259/4885
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device CRY1, CRY2, ATXN10 KDM4E 3893/4885LMNA 1827/4885POLB 3380/4885
US-20260059938-A1 ORGANIC EL ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE LEF1, LAGE3, EMC1 KDM4E 1461/4885LMNA 370/4885POLB 3413/4885
US-20090096356-A1 Light-emitting device material and light-emitting device PRMT9, CCNL2, MRPL9 KDM4E 2433/4885LMNA 1946/4885POLB 3388/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 KDM4E 1365/4885LMNA 2487/4885POLB 1259/4885
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT PYM1, CRY1, S100A10 KDM4E 1639/4885LMNA 388/4885POLB 3094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.