Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.50 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B known ✓ | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.46 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.46 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.46 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.46 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696954 | 1.00 | TDP1 (0.53) | TDP1ALDH1A1CYP3A4RAD51GAA | |
| Ammonia Solution, Strong SCHEMBL2315717 | 0.98 | TDP1 (0.52) | TDP1ALDH1A1CYP3A4RAD51GAA | |
| SCHEMBL715240 | 0.84 | NT5E (0.57) | TDP1ALDH1A1CYP3A4GAATHRB | |
| SCHEMBL30451696 | 0.83 | CA2 (0.57) | TDP1ALDH1A1CYP3A4GAATHRB | |
| SCHEMBL392987 | 0.83 | CA2 (0.57) | TDP1ALDH1A1CYP3A4GAATHRB | |
| SCHEMBL67062 | 0.81 | NT5E (0.59) | TDP1ALDH1A1CYP3A4GAATHRB | |
| SCHEMBL11674536 | 0.81 | TDP1 (0.53) | TDP1ALDH1A1CYP3A4GAATHRB | |
| SCHEMBL15976059 | 0.81 | TDP1 (0.53) | TDP1ALDH1A1CYP3A4GAATHRB | |
| SCHEMBL315765 | 0.81 | NT5E (0.59) | TDP1ALDH1A1CYP3A4GAATHRB | |
| SCHEMBL4622820 | 0.81 | ALDH1A1 (0.56) | TDP1ALDH1A1CYP3A4GAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114560848-B | Reactive light/sweat resistant composite color fastness improver and preparation method thereof | 山东中康国创先进印染技术研究院有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-114560848-A | Reactive light/light-perspiration resistant composite color fastness improver and preparation method thereof | 山东中康国创先进印染技术研究院有限公司 | 2022-05-31 | — | — | CN | claimed |
| CN-113200931-B | Reactive light-sweat-resistant composite fastness improver and preparation method thereof | 浙江理工大学上虞工业技术研究院有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-113200931-A | Reactive light-sweat-resistant composite fastness improver and preparation method thereof | 浙江理工大学上虞工业技术研究院有限公司 | 2021-08-03 | — | — | CN | claimed |
| US-20240167922-A1 | TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD | KYOTO UNIVERSITY (JP) | 2024-05-23 | — | — | US | disclosed |
| EP-4306927-A1 | TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD | Kyoto University (JP) | 2024-01-17 | — | — | EP | disclosed |
| CN-114560848-B | Reactive light/sweat resistant composite color fastness improver and preparation method thereof | 山东中康国创先进印染技术研究院有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-114560848-A | Reactive light/light-perspiration resistant composite color fastness improver and preparation method thereof | 山东中康国创先进印染技术研究院有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-113200931-B | Reactive light-sweat-resistant composite fastness improver and preparation method thereof | 浙江理工大学上虞工业技术研究院有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113200931-B | Reactive light-sweat-resistant composite fastness improver and preparation method thereof | 浙江理工大学上虞工业技术研究院有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113200931-A | Reactive light-sweat-resistant composite fastness improver and preparation method thereof | 浙江理工大学上虞工业技术研究院有限公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-113200931-A | Reactive light-sweat-resistant composite fastness improver and preparation method thereof | 浙江理工大学上虞工业技术研究院有限公司 | 2021-08-03 | — | — | CN | disclosed |
| WO-2004061530-A1 | POLYHYDROXYALKANOATE CONTAINING AMIDE GROUP, SULFONIC GROUP, AND SULFONATE ESTER GROUP, METHOD FOR PRODUCING THE SAME, AND CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2004-07-22 | — | — | WO | disclosed |
| WO-2004061529-A1 | NOVEL POLYHYDROXYALKANOATE HAVING AMIDE, SULFONIC ACID OR SULFONATE ESTER GROUP, CHARGE CONTROL AGENT AND TONER | CANON KABUSHIKI KAISHA (JP) | 2004-07-22 | — | — | WO | disclosed |
| CN-1112412-C | Diazo coupling process of polymer to synthesize high molecular epoxy resin dye | UNIV TSINGHUA (CN) | 2003-06-25 | — | — | CN | disclosed |
| CN-1284524-A | Diazo coupling process of polymer to synthesize high molecular epoxy resin dye | UNIV QINGHUA (CN) | 2001-02-21 | — | — | CN | disclosed |
| US-4457866-A | MEDICAL DIAGNOSIS | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |
| US-4217304-A | Continuous reduction process | CIBA-GEIGY AG (CH) | 1980-08-12 | — | — | US | disclosed |
| US-3998957-A | 1,1'-(UREYLENEBIS(SULFO-P-PHENYLENE)BISSULFO-1H,8H-INDAZOLO(2,3,4-CDE)BENZOTRIAZOL-9-IUM HYDROXIDE)INNER SALT | AMERICAN CYANAMID COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
| US-3942987-A | Photographic materials with ballasted, alkali cleavable azo dyes | EASTMAN KODAK COMPANY | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240167922-A1 | TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD | TST, TTR, ALB | THRB 3234/4885PDE4A 4879/4885PDE4B 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.