Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL3277139 | 0.94 | KDM4E (0.41) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL29283219 | 0.87 | KDM4E (0.56) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL8459071 | 0.84 | BBOX1 (0.40) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL29283223 | 0.83 | KDM4E (0.52) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL28899359 | 0.82 | GMNN (0.52) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| 2,2'-Dithiodiethanesulfonic Acid SCHEMBL18847 | 0.81 | KDM4E (0.48) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| 2,2'-Dithiodiethanesulfonic Acid SCHEMBL835029 | 0.81 | KDM4E (0.48) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL27175717 | 0.80 | GMNN (0.50) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL3890653 | 0.80 | GMNN (0.50) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| 2,2'-Dithiodiethanesulfonic Acid SCHEMBL835873 | 0.79 | KDM4E (0.46) | KDM4EMAPTALOX15ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8449957-B2 | Recording medium | CANON KABUSHIKI KAISHA (JP) | 2013-05-28 | — | — | US | disclosed |
| US-20120070591-A1 | RECORDING MEDIUM | CANON KABUSHIKI KAISHA (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2431189-A2 | Recording medium | Canon Kabushiki Kaisha (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-1694637-A4 | PROCESS FOR SYNTHESIZING DISULFIDES | BIONUMERIK PHARMACEUTICALS INC (US) | 2007-09-26 | — | — | EP | disclosed |
| EP-1694637-A2 | PROCESS FOR SYNTHESIZING DISULFIDES | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2006-08-30 | — | — | EP | disclosed |
| US-7053240-B2 | Process for synthesizing disulfides | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2006-05-30 | — | — | US | disclosed |
| WO-2005058005-A2 | PROCESS FOR SYNTHESIZING DISULFIDES | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2005-06-30 | — | — | WO | disclosed |
| US-20050137419-A1 | Process for synthesizing disulfides | BIONUMERIK PHARMACEUTICALS, INC. | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137419-A1 | Process for synthesizing disulfides | TST, CBS, STS | KDM4E 3498/4885MAPT 3687/4885ALOX15 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.