Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | BRD1 | O95696 | 2/20 | 0.43 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587888 | 0.84 | KEAP1 (0.54) | HSD11B1ACLYGAAMAPTSMN1; SMN2 | |
| SCHEMBL7580346 | 0.81 | KDM1A (0.63) | HSD11B1BRPF1TP53MAPTSMN1; SMN2 | |
| SCHEMBL7589336 | 0.81 | SLC22A12 (0.54) | CCR2ACLYSTAT3GLO1 | |
| SCHEMBL7597807 | 0.80 | CCR2 (0.71) | CCR2 | |
| SCHEMBL7590023 | 0.78 | CCR2 (0.51) | CCR2TP53GAAMAPTSMN1; SMN2 | |
| SCHEMBL7596280 | 0.77 | CCR2 (0.56) | CCR2BRPF1TP53GAAMAPT | |
| SCHEMBL7588944 | 0.77 | ALDH1A1 (0.56) | CCR2TP53GAAMAPTSMN1; SMN2 | |
| SCHEMBL7573875 | 0.76 | KEAP1 (0.55) | CCR2GAAMAPTSMN1; SMN2 | |
| SCHEMBL7595509 | 0.75 | SLC22A12 (0.56) | HSD11B1ACLYGLO1 | |
| SCHEMBL6831807 | 0.75 | MAPT (0.54) | HSD11B1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |