Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964386 | 0.86 | LMNA (0.39) | LMNAPTGS1PTGS2NPC1PKM | |
| SCHEMBL7965117 | 0.81 | CYP1A2 (0.58) | LMNAKMT2ACYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL7965119 | 0.81 | OPRM1 (0.39) | LMNANPC1PKMRAB9AOPRM1 | |
| SCHEMBL7963392 | 0.80 | ADRB2 (0.35) | LMNAOPRM1OPRD1KMT2ACYP1A2 | |
| SCHEMBL7962207 | 0.79 | ALDH1A1 (0.43) | LMNANPC1RAB9AOPRM1OPRD1 | |
| SCHEMBL7962696 | 0.79 | LTA4H (0.35) | LMNANPC1RAB9AOPRM1OPRD1 | |
| SCHEMBL7964944 | 0.78 | MEN1 (0.30) | KMT2A | |
| SCHEMBL7962741 | 0.77 | PDE10A (0.42) | NPC1RAB9AOPRM1OPRD1MAPT | |
| Fumaric Acid SCHEMBL7966209 | 0.75 | MAPT (0.38) | LMNANPC1HPGDKMT2AMAPT | |
| Fumaric Acid SCHEMBL7966218 | 0.75 | MAPT (0.38) | LMNANPC1HPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |