Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Orange G. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.46 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Orange G SCHEMBL29369740 | 1.00 | APP (1.00) | APPTHRBMAPK1ALDH1A1TDP1 | |
| Orange G SCHEMBL3873344 | 1.00 | APP (1.00) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL185277 | 0.99 | APP (0.98) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL93701 | 0.84 | APP (0.72) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL93700 | 0.84 | APP (0.72) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL29353967 | 0.84 | APP (0.72) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL10621059 | 0.83 | MAPK1 (0.73) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL1638375 | 0.83 | MAPK1 (0.73) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL29421649 | 0.83 | MAPK1 (0.73) | APPTHRBMAPK1ALDH1A1TDP1 | |
| Orange G SCHEMBL17279088 | 0.82 | APP (0.70) | APPTHRBMAPK1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10609 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4710086-A1 | TRACER METHODS FOR THE DETERMINATION OF SORBENT CONTENT IN SOILS | Regenesis Bioremediation Products (US) | 2026-03-18 | — | — | EP | claimed |
| EP-4701618-A1 | METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF A SHAMPOO | Henkel AG & Co. KGaA (DE) | 2026-03-04 | — | — | EP | claimed |
| EP-4701617-A1 | METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF AN AFTERTREATMENT AGENT CONTAINING PROTEIN HYDROLYSATE AND/OR AMINO ACID | Henkel AG & Co. KGaA (DE) | 2026-03-04 | — | — | EP | claimed |
| US-20260043720-A1 | STABILIZED TWO-PART HEMATOXYLIN SOLUTION UTILIZING pH ADJUSTMENT | VENTANA MED SYST INC (US) | 2026-02-12 | — | — | US | claimed |
| US-20260016380-A1 | METHOD FOR PREPARING DYEING SAMPLE | GENERAL BIOLOGICALS CORP (TW) | 2026-01-15 | — | — | US | claimed |
| EP-3723864-B1 | THICKENED ONE-COMPONENT HAIR TONER | HENKEL AG & CO KGAA (DE) | 2026-01-14 | — | — | EP | claimed |
| EP-4398865-B1 | MAKEUP KIT COMPRISING AN AQUEOUS MAKEUP COMPOSITION AND A CONTINUOUS OILY-PHASE FIXING COMPOSITION WITH A HYDROPHOBIC FILM-FORMING POLYMER | OREAL (FR) | 2025-10-29 | — | — | EP | claimed |
| US-12383478-B2 | Cosmetic product for dyeing keratin fibers | KAO CORPORATION (JP) | 2025-08-12 | — | — | US | claimed |
| CN-120136098-A | Preparation method of biogas residue carbon activator, application of biogas residue carbon activator and method for degrading organic pollutants in water | 合肥大学 | 2025-06-13 | — | — | CN | claimed |
| US-12313834-B2 | Paraffin shield coating for microscope slide | SHENZHEN PRS LIMITED (CN) | 2025-05-27 | — | — | US | claimed |
| US-4306956-A | USING TRACKING DYE | MILES LABORATORIES, INC. (US) | 1981-12-22 | — | — | US | claimed |
| US-4252880-A | A MIXTURE OF TRIARYLMETHANE AND METHINE DYE SENSITIZERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | claimed |
| US-4162207-A | TO SULFUR TRIOXIDE BY OXIDATION IN PRESENCE OF PHOTOSENSITIZER | BOYER STEPHEN K | 1979-07-24 | — | — | US | claimed |
| US-4142033-A | Inversion polymerization process for producing vinyl resins | THE B. F. GOODRICH COMPANY (US) | 1979-02-27 | — | — | US | claimed |
| EP-0000166-A1 | Internally coated reaction vessel for use in olefinic polymerization | The B.F. GOODRICH Company (US) | 1979-01-10 | — | — | EP | claimed |
| US-4104204-A | Photosensitization of oxygen to the singlet excited state using ion exchange resin to which is attached a dye and photooxidative waste water treatment | TEMPLE UNIVERSITY (US) | 1978-08-01 | — | — | US | claimed |
| US-4068059-A | ANTIDEPOSIT AGENTS | THE B. F. GOODRICH COMPANY (US) | 1978-01-10 | — | — | US | claimed |
| US-4025164-A | Liquid crystal display device for colored display of information with a selective polarizer | BBC BROWN BOVERI & COMPANY LIMITED (CH) | 1977-05-24 | — | — | US | claimed |
| US-3977870-A | ORGANIC DYESTUFF LAYER | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | claimed |
| US-3973959-A | Electrophotographic recording material and process for its manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | claimed |