Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.98 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.47 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Orange G SCHEMBL81967 | 0.99 | APP (1.00) | APPTHRBMAPK1ALDH1A1TDP1 | |
| Orange G SCHEMBL29369740 | 0.99 | APP (1.00) | APPTHRBMAPK1ALDH1A1TDP1 | |
| Orange G SCHEMBL3873344 | 0.99 | APP (1.00) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL1098585 | 0.83 | APP (0.69) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL461768 | 0.83 | APP (0.69) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL110351 | 0.83 | APP (0.69) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL29353967 | 0.83 | APP (0.72) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL93700 | 0.83 | APP (0.72) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL93701 | 0.83 | APP (0.72) | APPTHRBMAPK1ALDH1A1TDP1 | |
| SCHEMBL7921324 | 0.82 | APP (0.67) | APPTHRBMAPK1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4701617-A1 | METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF AN AFTERTREATMENT AGENT CONTAINING PROTEIN HYDROLYSATE AND/OR AMINO ACID | Henkel AG & Co. KGaA (DE) | 2026-03-04 | — | — | EP | claimed |
| EP-4701618-A1 | METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF A SHAMPOO | Henkel AG & Co. KGaA (DE) | 2026-03-04 | — | — | EP | claimed |
| EP-3723864-B1 | THICKENED ONE-COMPONENT HAIR TONER | HENKEL AG & CO KGAA (DE) | 2026-01-14 | — | — | EP | claimed |
| US-20250340460-A1 | METAL OXIDE MODIFIED ZEOLITIC IMIDAZOLATE FRAMEWORK-8 FOR WATER TREATMENT | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2025-11-06 | — | — | US | claimed |
| EP-4398865-B1 | MAKEUP KIT COMPRISING AN AQUEOUS MAKEUP COMPOSITION AND A CONTINUOUS OILY-PHASE FIXING COMPOSITION WITH A HYDROPHOBIC FILM-FORMING POLYMER | OREAL (FR) | 2025-10-29 | — | — | EP | claimed |
| US-12383478-B2 | Cosmetic product for dyeing keratin fibers | KAO CORPORATION (JP) | 2025-08-12 | — | — | US | claimed |
| EP-3873402-B1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF AN ORGANIC SILICON COMPOUND, AN ALKALISING AGENT AND A FILM-FORMING POLYMER | HENKEL AG & CO KGAA (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-3873416-B1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF A FIRST AGENT (A) HAVING A SILANE AND A CHROMOPHORIC COMPOUND, AND A SECOND AGENT (B) HAVING A FILM-FORMING POLYMER | HENKEL AG & CO KGAA (DE) | 2025-02-26 | — | — | EP | claimed |
| US-20240423887-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KAO CORPORATION (JP) | 2024-12-26 | — | — | US | claimed |
| CN-119108665-A | Electrolyte additive, aqueous electrolyte and zinc-based energy storage device | 清华大学深圳国际研究生院 | 2024-12-10 | — | — | CN | claimed |
| US-11382851-B2 | Hair dye composition containing at least one organic silicon compound, a direct dye and a film forming hydrophobic polymer | HENKEL AG & CO. KGAA (DE) | 2022-07-12 | — | — | US | claimed |
| EP-2883531-B1 | Bleaching and coloring composition for hair | KAO CORP (JP) | 2022-06-15 | — | — | EP | claimed |
| US-11331258-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, an oligoalkylsiloxane and a dyeing compound | HENKEL AG & CO. KGAA (DE) | 2022-05-17 | — | — | US | claimed |
| CN-114487170-A | Method for detecting illegally added compounds in food | 张缤 | 2022-05-13 | — | — | CN | claimed |
| EP-3989920-A1 | ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF | Living Proof, Inc. (US) | 2022-05-04 | — | — | EP | claimed |
| CN-114388077-A | Traditional Chinese medicine dyed material database based on micro-focusing Raman technology and application thereof in identification of traditional Chinese medicine dyed materials | 成都市食品药品检验研究院 | 2022-04-22 | — | — | CN | claimed |
| US-11291622-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound and a silicon oil | HENKEL AG & CO. KGAA (DE) | 2022-04-05 | — | — | US | claimed |
| CN-114222555-A | Additives for colorants and methods of use thereof | 生活实验公司 | 2022-03-22 | — | — | CN | claimed |
| CN-114062546-A | Method for simultaneously screening 8 illegal coloring agents in muscle-relaxing and blood-circulation-promoting tablets | 巩长芹 | 2022-02-18 | — | — | CN | claimed |
| EP-2930126-B1 | Fashionable aerosol dye | HENKEL AG & CO KGAA (DE) | 2019-10-09 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11291622-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound and a silicon oil | KRT18, MKI67, DSG1 | THRB 4573/4885APP 1570/4885MAPK1 2306/4885 |
| US-12383478-B2 | Cosmetic product for dyeing keratin fibers | KRT18, H1-2, H1-0 | THRB 2470/4885APP 3451/4885MAPK1 192/4885 |
| US-11331258-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, an oligoalkylsiloxane and a dyeing compound | KRT18, MKI67, PCNA | THRB 4768/4885APP 1785/4885MAPK1 4042/4885 |
| US-20240423887-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KRT18, COL14A1, COL1A1 | THRB 2991/4885APP 1888/4885MAPK1 1784/4885 |
| US-11382851-B2 | Hair dye composition containing at least one organic silicon compound, a direct dye and a film forming hydrophobic polymer | KRT18, DSG1, CUTA | THRB 2660/4885APP 604/4885MAPK1 2029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.