Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143591 | 0.85 | PPARG (0.56) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL6696866 | 0.84 | TDP1 (0.54) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL5085480 | 0.84 | PPARG (0.71) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL17491378 | 0.79 | LMNA (0.41) | PPARGTDP1KMT2ALMNATSHR | |
| SCHEMBL442438 | 0.79 | ALDH1A1 (0.52) | TDP1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL4577944 | 0.79 | PPARG (0.65) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL14267744 | 0.78 | ALOX5 (0.49) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL6243415 | 0.77 | PPARG (0.63) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL336833 | 0.77 | PPARG (0.63) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL1268573 | 0.77 | PTGDR2 (0.39) | PPARGTDP1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177522-B1 | NOVEL CARBAPENEM DERIVATIVES | XUANZHU PHARMA CO LTD (CN) | 2013-09-04 | — | — | EP | claimed |
| US-7579373-B2 | Targeted bisplatinum polyamines as pro-drugs: selective release of platinum | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2009-08-25 | — | — | US | claimed |
| EP-1427739-A4 | TARGETED BISPLATINUM POLYAMINES AS PRO-DRUGS: SELECTIVE RELEASE OF PLATINUM | UNIV VIRGINIA COMMONWEALTH (US) | 2008-02-13 | — | — | EP | claimed |
| EP-1427739-A1 | TARGETED BISPLATINUM POLYAMINES AS PRO-DRUGS: SELECTIVE RELEASE OF PLATINUM | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2004-06-16 | — | — | EP | claimed |
| US-20030114433-A1 | Targeted bisplatinum polyamines as pro-drugs: selective release of platinum | VIRGINIA COMMONWEALTH UNIVERSITY | 2003-06-19 | — | — | US | claimed |
| WO-2003018594-A1 | TARGETED BISPLATINUM POLYAMINES AS PRO-DRUGS: SELECTIVE RELEASE OF PLATINUM | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2003-03-06 | — | — | WO | claimed |
| US-5837873-A | PROTECTED OXYDIAMINES | ABBOTT LABORATORIES (US) | 1998-11-17 | — | — | US | claimed |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | MELINTA SUBSIDIARY CORP. (US) | 2024-06-04 | — | — | US | disclosed |
| US-11975110-B2 | Cationic polymers | TRANSLATE BIO, INC. (US) | 2024-05-07 | — | — | US | disclosed |
| EP-4356736-A2 | SYNTHESIS OF BORONATE SALTS | Melinta Therapeutics, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-3604316-B1 | SYNTHESIS OF BORONATE SALTS | MELINTA THERAPEUTICS INC (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20210113483-A1 | Cationic Polymers | TRANSLATE BIO, INC. | 2021-04-22 | — | — | US | disclosed |
| EP-3746496-A1 | CATIONIC POLYMERS | Translate Bio, Inc. (US) | 2020-12-09 | — | — | EP | disclosed |
| EP-0807118-A2 | NOVEL COMPOUNDS AND METHODS FOR MAKING AND USING SAME | GILEAD SCIENCES, INC. (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1997014689-A1 | ARYL-PIPERAZINE CYCLIC AMINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | PIERRE FABRE MEDICAMENT (FR) | 1997-04-24 | — | — | WO | disclosed |
| EP-0759917-A1 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | GILEAD SCIENCES, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1996026933-A9 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | — | 1996-11-28 | — | — | WO | disclosed |
| WO-1996033200-A1 | NOVEL COMPOUNDS AND METHODS FOR THERAPY | ÚSTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VED C^¿ESKÉ REPUBLIKY (CZ) | 1996-10-24 | — | — | WO | disclosed |
| WO-1996023801-A2 | NOVEL COMPOUNDS AND METHODS FOR MAKING AND USING SAME | GILEAD SCIENCES, INC. (US) | 1996-08-08 | — | — | WO | disclosed |
| US-4508723-A | 6-Azaoligocycloalkylmethyleneaminopenam compounds | CIBA GEIGY CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210113483-A1 | Cationic Polymers | NSUN3, RNMT, POLRMT | PPARG 3575/4885TDP1 397/4885KMT2A 2084/4885 |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | ADH5, ADH1A, ADH7 | PPARG 2580/4885TDP1 1727/4885KMT2A 3000/4885 |
| US-11975110-B2 | Cationic polymers | NSUN3, RNMT, POLRMT | PPARG 3575/4885TDP1 397/4885KMT2A 2084/4885 |
| US-20030114433-A1 | Targeted bisplatinum polyamines as pro-drugs: selective release of platinum | SRM, SMS, PARG | PPARG 4082/4885TDP1 1009/4885KMT2A 2704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.