SCHEMBL9100974

SCHEMBL9100974

COc1cc(C=C(C(C)=O)C(C)=O)cc(OC)c1OC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 2/20 0.67
▸ TDP1 Q9NUW8 1/20 0.67
▸ MAPT P10636 2/20 0.63
▸ HTT P42858 1/20 0.59
▸ HPGD P15428 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ HTR1A P08908 1/20 0.54
▸ HTR2C P28335 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.54
▸ TUBB1 Q9H4B7 5/20 0.51
▸ TUBB4A P04350 2/20 0.50
▸ TUBB P07437 2/20 0.50
▸ TUBA3C P0DPH7 2/20 0.50
▸ TUBA1B P68363 2/20 0.50
▸ TUBA4A P68366 2/20 0.50
▸ TUBB4B P68371 2/20 0.50
▸ TUBB3 Q13509 2/20 0.50
▸ TUBB2A Q13885 2/20 0.50
▸ TUBB8 Q3ZCM7 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10847801 0.91 GAA (0.57) GAATDP1MAPTHTTHPGD
SCHEMBL9689450 0.91 GAA (0.57) GAATDP1MAPTHTTHPGD
SCHEMBL11739418 0.90 MAPT (0.58) GAATDP1MAPTHTTHPGD
SCHEMBL11739407 0.90 MAPT (0.58) GAATDP1MAPTHTTHPGD
SCHEMBL8630136 0.85 HTR1A (0.59) GAATDP1MAPTHTTHPGD
SCHEMBL20162259 0.85 GAA (0.50) GAATDP1MAPTHTTHPGD
SCHEMBL10671345 0.85 MEN1 (0.50) GAATDP1MAPTHTTHPGD
SCHEMBL10671337 0.85 MEN1 (0.50) GAATDP1MAPTHTTHPGD
SCHEMBL20162262 0.85 GAA (0.50) GAATDP1MAPTHTTHPGD
SCHEMBL14462723 0.84 HPGD (0.68) GAATDP1MAPTHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072721-A1 COMPOSITIONS UVAGELESS LLC (US) 2025-04-03 — — WO claimed
US-20180207080-A1 COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS MERCK PATENT GMBH (DE) 2018-07-26 — — US claimed
EP-3322400-A1 COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS Merck Patent GmbH (DE) 2018-05-23 — — EP claimed
US-20150182431-A1 Compositions and Methods for Treatment of Hair with Reduced Hair Damage SYTHEON LTD (US) 2015-07-02 — — US claimed
US-20260034048-A1 STABILIZATION OF AVOBENZONE IN COSMETIC SUNSCREENS BEIERSDORF AG (DE) 2026-02-05 — — US disclosed
US-20260034037-A1 STABILIZED AVOBENZONE IN COSMETIC SUNSCREEN COMPOSITIONS BEIERSDORF AG (DE) 2026-02-05 — — US disclosed
EP-4673106-A1 COSMETIC COMPOSITION WITH ZINC OXIDE AND BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE L'OREAL (FR) 2026-01-07 — — EP disclosed
US-20250387312-A1 COSMETIC FORMULATIONS COMPRISING A BIOPOLYMER 11584022 CANADA INC. (CA) 2025-12-25 — — US disclosed
EP-4547194-A1 COSMETIC FORMULATIONS COMPRISING STABLE HOMOGENEOUS AQUEOUS SUSPENSION OF BIOPOLYMERS 11584022 Canada Inc. (CA) 2025-05-07 — — EP disclosed
CN-119894483-A Cosmetic preparation comprising a stable homogeneous aqueous suspension of a biopolymer 11584022加拿大有限公司 2025-04-25 — — CN disclosed
CN-113573689-B Sunscreen composition comprising butyl methoxydibenzoylmethane, triazine derivative and light stabilizer 巴斯夫欧洲公司 2025-04-15 — — CN disclosed
WO-2025072721-A1 COMPOSITIONS UVAGELESS LLC (US) 2025-04-03 — — WO disclosed
EP-2649033-B1 COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS SYTHEON LTD (US) 2018-10-17 — — EP disclosed
US-20180207080-A1 COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS MERCK PATENT GMBH (DE) 2018-07-26 — — US disclosed
EP-3322400-A1 COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS Merck Patent GmbH (DE) 2018-05-23 — — EP disclosed
US-20150182431-A1 Compositions and Methods for Treatment of Hair with Reduced Hair Damage SYTHEON LTD (US) 2015-07-02 — — US disclosed
US-8617528-B2 Compositions and methods for stabilizing ingredients using 2,4-pentanedione compounds SYTHEON LTD. (US) 2013-12-31 — — US disclosed
EP-2649033-A2 COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS Sytheon Ltd. (US) 2013-10-16 — — EP disclosed
WO-2012078546-A2 COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS SYTHEON LTD. (US) 2012-06-14 — — WO disclosed
US-20120141395-A1 COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS SYTHEON LIMITED (US) 2012-06-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250387312-A1 COSMETIC FORMULATIONS COMPRISING A BIOPOLYMER COL2A1, COL1A1, COL14A1 GAA 1324/4885TDP1 2206/4885MAPT 57/4885
US-20180207080-A1 COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS LPO, CAT, GPX4 GAA 1205/4885TDP1 895/4885MAPT 1864/4885
US-20260034037-A1 STABILIZED AVOBENZONE IN COSMETIC SUNSCREEN COMPOSITIONS TYR, RAD23B, CYP8B1 GAA 3060/4885TDP1 2673/4885MAPT 2155/4885
US-20260034048-A1 STABILIZATION OF AVOBENZONE IN COSMETIC SUNSCREENS RUVBL1, CUTA, TTI1 GAA 3334/4885TDP1 2436/4885MAPT 747/4885
US-20120141395-A1 COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS HPD, GPX4, RBP4 GAA 3228/4885TDP1 3450/4885MAPT 385/4885
US-20150182431-A1 Compositions and Methods for Treatment of Hair with Reduced Hair Damage GPX4, COX5A, COX5B GAA 4505/4885TDP1 2383/4885MAPT 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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