Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethoxysulfuron. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924543 | 0.82 | CDK1 (0.39) | GAACDK1 | |
| SCHEMBL7643173 | 0.82 | CDK1 (0.37) | MAPTGAAKDM4ENPC1ALDH1A1 | |
| SCHEMBL116869 | 0.81 | NPC1 (0.31) | NPC1 | |
| SCHEMBL915255 | 0.80 | CDK1 (0.38) | GAACDK1 | |
| Ethoxysulfuron SCHEMBL29386240 | 0.76 | GAA (0.53) | TP53RXFP1MAPTGAAHSD17B10 | |
| Ethoxysulfuron SCHEMBL65311 | 0.76 | GAA (0.53) | TP53RXFP1MAPTGAAHSD17B10 | |
| Ethoxysulfuron SCHEMBL8365899 | 0.76 | ALDH1A1 (0.43) | TP53RXFP1MAPTGAAKDM4E | |
| Foramsulfuron SCHEMBL914629 | 0.76 | CDK1 (0.64) | GAACDK1 | |
| Ethoxysulfuron SCHEMBL2323273 | 0.76 | GAA (0.52) | TP53RXFP1MAPTGAAHSD17B10 | |
| Ethoxysulfuron SCHEMBL28150239 | 0.76 | GAA (0.52) | TP53RXFP1MAPTGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867946-B2 | Liquid formulation | BAYER CROPSCIENCE AG (DE) | 2011-01-11 | — | — | US | disclosed |
| US-20060205596-A1 | Liquid formulation | BAYER CROPSCIENCE GMBH (DE) | 2006-09-14 | — | — | US | disclosed |
| US-20050026786-A1 | Oil suspension concentrate | BAYER CROPSCIENCE GMBH (DE) | 2005-02-03 | — | — | US | disclosed |
| US-20050026787-A1 | Liquid formulation | BAYER CROPSCIENCE GMBH (DE) | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026786-A1 | Oil suspension concentrate | LIPA, BLVRB, DDT | TP53 3595/4885RXFP1 3638/4885MAPT 2040/4885 |
| US-20050026787-A1 | Liquid formulation | SOD1, GLO1, MDM2 | TP53 151/4885RXFP1 3528/4885MAPT 16/4885 |
| US-20060205596-A1 | Liquid formulation | SOD1, GLO1, MDM2 | TP53 151/4885RXFP1 3528/4885MAPT 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.