SCHEMBL93906

SCHEMBL93906

Nc1nc2[nH]cc(CN[C@H]3C=C[C@H](O)[C@@H]3O)c2c(=O)[nH]1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TYMS P04818 8/20 0.41
FOLR1 P15328 1/20 0.39
SLC19A1 P41440 1/20 0.39
SLC46A1 Q96NT5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19929101 1.00 TYMS (0.41) TYMSFOLR1SLC19A1SLC46A1
SCHEMBL21343009 1.00 TYMS (0.41) TYMSFOLR1SLC19A1SLC46A1
SCHEMBL19929273 1.00 TYMS (0.41) TYMSFOLR1SLC19A1SLC46A1
SCHEMBL19929270 1.00 TYMS (0.41) TYMSFOLR1SLC19A1SLC46A1
SCHEMBL19929275 1.00 TYMS (0.41) TYMSFOLR1SLC19A1SLC46A1
SCHEMBL23005880 1.00 TYMS (0.41) TYMSFOLR1SLC19A1SLC46A1
SCHEMBL15972267 0.84 PNP (0.32)
Hydrochloric Acid SCHEMBL29354653 0.83 PNP (0.32)
SCHEMBL21343010 0.82 TYMS (0.41) TYMSFOLR1SLC19A1SLC46A1
SCHEMBL23109473 0.82 TYMS (0.40) TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
EP-4743093-A1 METABOLITES FOR TRNA MODIFICATION The University of Chicago (US) 2026-05-20 EP claimed
WO-2025071519-A1 A FORMULATION FOR USE IN THE TREATMENT OF ALZHEIMER'S DISEASE T.C. USKUDAR UNIVERSITESI (TR) 2025-04-03 WO claimed
WO-2025061911-A1 METHODS OF PRODUCING NUCLEOTIDE TRIPHOSPHATES (NTPS) GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2025-03-27 WO claimed
WO-2025015197-A1 METABOLITES FOR TRNA MODIFICATION THE UNIVERSITY OF CHICAGO (US) 2025-01-16 WO claimed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US claimed
US-20230295165-A1 COMPOUNDS THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) 2023-09-21 US claimed
US-20230286987-A1 COMPOUNDS THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) 2023-09-14 US claimed
US-11684611-B2 Compounds for treating diseases associated with a mitochondrial dysfunction AMABIOTICS (FR) 2023-06-27 US claimed
EP-4188932-A1 COMPOUNDS The Provost, Fellows, Foundation Scholars and the other members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth, (IE) 2023-06-07 EP claimed
US-20110081675-A1 Metabolic Biomarkers Of Drug-Induced Cardiotoxicity WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-04-07 US claimed
US-6596701-B1 Identifying abnormalities in SAM pathways; screening; sampling MEDIQUEST THERAPEUTICS, INC. 2003-07-22 US claimed
US-20030078231-A1 Orthomolecular sulpho-adenosylmethionine derivatives with antioxidant properties WILBURN MICHAEL D (US) 2003-04-24 US claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
EP-1221615-A2 S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy ORIDIGM CORPORATION (US) 2002-07-10 EP claimed
US-6020139-A S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy ORIDIGM CORPORATION (US) 2000-02-01 US claimed
EP-0824345-A4 S-ADENOSYL METHIONINE REGULATION OF METABOLIC PATHWAYS AND ITS USE IN DIAGNOSIS AND THERAPY ORIDIGM CORP (US) 1999-08-25 EP claimed
EP-0824345-A1 S-ADENOSYL METHIONINE REGULATION OF METABOLIC PATHWAYS AND ITS USE IN DIAGNOSIS AND THERAPY ORIDIGM CORPORATION (US) 1998-02-25 EP claimed
WO-1996033703-A2 S-ADENOSYL METHIONINE REGULATION OF METABOLIC PATHWAYS AND ITS USE IN DIAGNOSIS AND THERAPY ORIDIGM CORPORATION (US) 1996-10-31 WO claimed
US-5312900-A Polypeptides LA JOLLA CANCER RESEARCH FOUNDATION (US) 1994-05-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295165-A1 COMPOUNDS NR3C1, NR3C2, CBR3 TYMS 4575/4885FOLR1 1089/4885SLC19A1 3576/4885
US-20030078231-A1 Orthomolecular sulpho-adenosylmethionine derivatives with antioxidant properties MAT1A, LPO, TPMT TYMS 1249/4885FOLR1 3252/4885SLC19A1 1833/4885
US-20230286987-A1 COMPOUNDS HAX1, NHERF1, CXCR1 TYMS 4374/4885FOLR1 2073/4885SLC19A1 2488/4885
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 TYMS 2697/4885FOLR1 1186/4885SLC19A1 1979/4885
US-20030007961-A1 Orthomolecular vitamin E derivatives RBP4, RBP1, VDR TYMS 4689/4885FOLR1 3463/4885SLC19A1 3262/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF TYMS 940/4885FOLR1 1257/4885SLC19A1 185/4885
US-11684611-B2 Compounds for treating diseases associated with a mitochondrial dysfunction NDUFAB1, FH, TFAM TYMS 3412/4885FOLR1 3377/4885SLC19A1 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.