Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28248910 | 0.92 | KDM4E (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27855771 | 0.86 | KDM4E (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27855772 | 0.85 | CASP7 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5407130 | 0.84 | KDM4E (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27875807 | 0.82 | CYP1A2 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7919789 | 0.81 | THRB (0.40) | TP53HSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL5407133 | 0.80 | KDM4E (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28684961 | 0.80 | MAPT (0.50) | TP53HSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL27668976 | 0.79 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28093812 | 0.79 | G6PD (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200093817-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2020-03-26 | — | — | US | claimed |
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | claimed |
| US-20170312270-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2017-11-02 | — | — | US | claimed |
| EP-3226907-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS AND MAKING AND USE THEREOF | Kempharm, Inc. (US) | 2017-10-11 | — | — | EP | claimed |
| EP-3223819-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE | Kempharm, Inc. (US) | 2017-10-04 | — | — | EP | claimed |
| CN-106999486-A | Benzoic acid conjugate, benzoic acid derivative conjugate and the heteroaryl carboxylic acid conjugate of Oxycodone | 凯姆制药公司 | 2017-08-01 | — | — | CN | claimed |
| CN-106999487-A | Benzoic acid conjugate, benzoic acid derivative conjugate and the heteroaryl carboxylic acid conjugate of Oxymorphone, its prodrug, preparation and application | 凯姆制药公司 | 2017-08-01 | — | — | CN | claimed |
| US-20160168160-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2016-06-16 | — | — | US | claimed |
| WO-2016089951-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS AND MAKING AND USE THEREOF | KEMPHARM, INC. (US) | 2016-06-09 | — | — | WO | claimed |
| WO-2016086113-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE | KEMPHARM, INC. (US) | 2016-06-02 | — | — | WO | claimed |
| US-20160151352-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2016-06-02 | — | — | US | claimed |
| CN-104136031-A | Benzoic acid, benzoic acid derivative and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and using thereof | KEMPHARM INC | 2014-11-05 | — | — | CN | claimed |
| EP-2771002-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | Kempharm, Inc. (US) | 2014-09-03 | — | — | EP | claimed |
| US-20130150395-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | KEMPHARM, INC. (US) | 2013-06-13 | — | — | US | claimed |
| WO-2013063204-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | KEMPHARM, INC. (US) | 2013-05-02 | — | — | WO | claimed |
| US-20120142719-A1 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | ALTER DOMUS (US) LLC | 2012-06-07 | — | — | US | claimed |
| CN-102480959-A | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM INC | 2012-05-30 | — | — | CN | claimed |
| EP-2448407-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | Kempharm, Inc. (US) | 2012-05-09 | — | — | EP | claimed |
| US-20110002990-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2011-01-06 | — | — | US | claimed |
| US-12590065-B2 | Levorphanol prodrugs and processes for making and using them | ZEVRA THERAPEUTICS, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| US-20250161468-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| US-20250032479-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ZEVRA THERAPEUTICS INC (US) | 2025-01-30 | — | — | US | disclosed |
| US-20240390507-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2024-11-28 | — | — | US | disclosed |
| US-20240317688-A1 | DEXTRORPHAN PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ZEVRA THERAPEUTICS, INC. | 2024-09-26 | — | — | US | disclosed |
| US-12076316-B2 | Levorphanol prodrugs and processes for making and using them | ZEVRA THERAPEUTICS INC. | 2024-09-03 | — | — | US | disclosed |
| US-12012384-B2 | Dextrorphan prodrugs and processes for making and using them | ZEVRA THERAPEUTICS, INC. (US) | 2024-06-18 | — | — | US | disclosed |
| US-20240165106-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2024-05-23 | — | — | US | disclosed |
| US-20230241054-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| US-20220096463-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2022-03-31 | — | — | US | disclosed |
| US-20220089544-A1 | DEXTRORPHAN PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2022-03-24 | — | — | US | disclosed |
| US-20220054479-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2022-02-24 | — | — | US | disclosed |
| US-11214544-B2 | Dextrorphan prodrugs and processes for making and using them | KEMPHARM, INC. (US) | 2022-01-04 | — | — | US | disclosed |
| US-11197933-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | ELYSIUM THERAPEUTICS, INC. (US) | 2021-12-14 | — | — | US | disclosed |
| US-11154549-B2 | Opioid compositions resistant to overdose and abuse | ELYSIUM THERAPEUTICS, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-11129825-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | ELYSIUM THERAPEUTICS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20210002226-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2021-01-07 | — | — | US | disclosed |
| US-20200392087-A1 | DEXTRORPHAN PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2020-12-17 | — | — | US | disclosed |
| US-10849981-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KemPham, Inc. (US) | 2020-12-01 | — | — | US | disclosed |
| US-10758528-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2020-09-01 | — | — | US | disclosed |
| US-10654863-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2020-05-19 | — | — | US | disclosed |
| US-20200101166-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2020-04-02 | — | — | US | disclosed |
| US-20200093817-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2020-03-26 | — | — | US | disclosed |
| US-10577376-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2020-03-03 | — | — | US | disclosed |
| US-20200030316-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2020-01-30 | — | — | US | disclosed |
| US-10544153-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxycodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-10463660-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| EP-3560336-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | Kempharm, Inc. (US) | 2019-10-30 | — | — | EP | disclosed |
| US-10441661-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2019-10-15 | — | — | US | disclosed |
| EP-2448407-B1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | KEMPHARM INC (US) | 2019-09-25 | — | — | EP | disclosed |
| US-10358452-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof | KEMPHARM, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| US-10351573-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof | KEMPHARM, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-10335406-B2 | Opioid compositions resistant to overdose and abuse | ELYSIUM THERAPEUTICS, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20190192670-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2019-06-27 | — | — | US | disclosed |
| US-20190183884-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2019-06-20 | — | — | US | disclosed |
| US-20190160175-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2019-05-30 | — | — | US | disclosed |
| US-10258696-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| US-10251878-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | ELYSIUM THERAPEUTICS, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-20190048018-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2019-02-14 | — | — | US | disclosed |
| US-10144740-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxycodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2018-12-04 | — | — | US | disclosed |
| US-20180339056-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2018-11-29 | — | — | US | disclosed |
| US-20180338968-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2018-11-29 | — | — | US | disclosed |
| WO-2018191474-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | KEMPHARM, INC. (US) | 2018-10-18 | — | — | WO | disclosed |
| WO-2018191477-A1 | DEXTRORPHAN PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | KEMPHARM, INC. (US) | 2018-10-18 | — | — | WO | disclosed |
| WO-2018191472-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | KEMPHARM, INC. (US) | 2018-10-18 | — | — | WO | disclosed |
| WO-2018170465-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. (US) | 2018-09-20 | — | — | WO | disclosed |
| US-10071091-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2018-09-11 | — | — | US | disclosed |
| US-10064956-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2018-09-04 | — | — | US | disclosed |
| EP-3355885-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | Elysium Therapeutics, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| US-20180177883-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2018-06-28 | — | — | US | disclosed |
| US-20180104352-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2018-04-19 | — | — | US | disclosed |
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
| US-20180065975-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2018-03-08 | — | — | US | disclosed |
| US-20180064820-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2018-03-08 | — | — | US | disclosed |
| US-9872915-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20170368058-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2017-12-28 | — | — | US | disclosed |
| US-9850252-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxycodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-9849185-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-9808452-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | ELYSIUM THERAPEUTICS, INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170312270-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2017-11-02 | — | — | US | disclosed |
| EP-3226907-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS AND MAKING AND USE THEREOF | Kempharm, Inc. (US) | 2017-10-11 | — | — | EP | disclosed |
| EP-3223819-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE | Kempharm, Inc. (US) | 2017-10-04 | — | — | EP | disclosed |
| US-20170226118-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof | ALTER DOMUS (US) LLC | 2017-08-10 | — | — | US | disclosed |
| CN-106999486-A | Benzoic acid conjugate, benzoic acid derivative conjugate and the heteroaryl carboxylic acid conjugate of Oxycodone | 凯姆制药公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106999487-A | Benzoic acid conjugate, benzoic acid derivative conjugate and the heteroaryl carboxylic acid conjugate of Oxymorphone, its prodrug, preparation and application | 凯姆制药公司 | 2017-08-01 | — | — | CN | disclosed |
| US-9682076-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-20170143696-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USES THEREOF | ALTER DOMUS (US) LLC | 2017-05-25 | — | — | US | disclosed |
| US-20170143839-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2017-05-25 | — | — | US | disclosed |
| US-9650387-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof | KEMPHARM, INC. (US) | 2017-05-16 | — | — | US | disclosed |
| WO-2017070576-A1 | METHODS AND COMPOSITIONS FOR REGULATING CONVERSION OF A PRODRUG TO AN ACTIVE PHARMACEUTICAL INGREDIENT | ACURA PHARMACEUTICALS, INC. (US) | 2017-04-27 | — | — | WO | disclosed |
| US-20170112825-A1 | METHODS AND COMPOSITIONS FOR REGULATING CONVERSION OF A PRODRUG TO AN ACTIVE PHARMACEUTICAL INGREDIENT | ACURA PHARMACEUTICALS, INC. (US) | 2017-04-27 | — | — | US | disclosed |
| US-20170100390-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2017-04-13 | — | — | US | disclosed |
| US-9566343-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-9549923-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof | KEMPHARM, INC. (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160200731-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof | ALTER DOMUS (US) LLC | 2016-07-14 | — | — | US | disclosed |
| CN-105749294-A | Benzoic Acid, Benzoic Acid Derivatives And Heteroaryl Carboxylic Acid Conjugates Of Hydromorphone, Prodrugs, Methods Of Making And Use Thereof | 凯姆制药公司 | 2016-07-13 | — | — | CN | disclosed |
| US-20160193204-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof | ALTER DOMUS (US) LLC | 2016-07-07 | — | — | US | disclosed |
| US-20160168160-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2016-06-16 | — | — | US | disclosed |
| WO-2016089951-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS AND MAKING AND USE THEREOF | KEMPHARM, INC. (US) | 2016-06-09 | — | — | WO | disclosed |
| WO-2016086113-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE | KEMPHARM, INC. (US) | 2016-06-02 | — | — | WO | disclosed |
| US-20160151352-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2016-06-02 | — | — | US | disclosed |
| CN-104136031-B | Benzoic acid, benzoic acid derivative and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and using thereof | KEMPHARM, INC. (US) | 2016-05-04 | — | — | CN | disclosed |
| US-20150335759-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2015-11-26 | — | — | US | disclosed |
| US-9132125-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2015-09-15 | — | — | US | disclosed |
| US-20150087667-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2015-03-26 | — | — | US | disclosed |
| US-20150065536-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof | ALTER DOMUS (US) LLC | 2015-03-05 | — | — | US | disclosed |
| US-8927716-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140330021-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2014-11-06 | — | — | US | disclosed |
| CN-104136031-A | Benzoic acid, benzoic acid derivative and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and using thereof | KEMPHARM INC | 2014-11-05 | — | — | CN | disclosed |
| US-8828978-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| EP-2771002-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | Kempharm, Inc. (US) | 2014-09-03 | — | — | EP | disclosed |
| US-8816083-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8759368-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KemPharma, Inc. (US) | 2014-06-24 | — | — | US | disclosed |
| US-8748413-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2014-06-10 | — | — | US | disclosed |
| CN-102480959-B | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM INC | 2014-05-21 | — | — | CN | disclosed |
| US-20130259909-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | KEMPHARM, INC. (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130252994-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | KEMPHARM, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130245265-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2013-09-19 | — | — | US | disclosed |
| US-20130150395-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | KEMPHARM, INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-8461137-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| WO-2013063204-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | KEMPHARM, INC. (US) | 2013-05-02 | — | — | WO | disclosed |
| US-20120142719-A1 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | ALTER DOMUS (US) LLC | 2012-06-07 | — | — | US | disclosed |
| CN-102480959-A | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | KEMPHARM INC | 2012-05-30 | — | — | CN | disclosed |
| EP-2448407-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | Kempharm, Inc. (US) | 2012-05-09 | — | — | EP | disclosed |
| US-20110002990-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2011-01-06 | — | — | US | disclosed |
| US-20110002990-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130259909-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | CYP2B6, CYP3A43, CYP2D6 | GABRP 316/4885GABRD 104/4885GABRA1 167/4885 |
| US-20200093817-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | GABRP 710/4885GABRD 2174/4885GABRA1 1819/4885 |
| US-20150087667-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | CYP2B6, CYP3A43, CYP2D6 | GABRP 316/4885GABRD 104/4885GABRA1 167/4885 |
| US-20190048018-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | GABRP 77/4885GABRD 21/4885GABRA1 32/4885 |
| US-12012384-B2 | Dextrorphan prodrugs and processes for making and using them | OGFR, OPRM1, CYP4F3 | GABRP 404/4885GABRD 578/4885GABRA1 1301/4885 |
| US-10351573-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof | CYP2B6, CYP3A43, CYP2D6 | GABRP 330/4885GABRD 110/4885GABRA1 174/4885 |
| US-10251878-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | OPRK1, OPRM1, CYP3A5 | GABRP 1681/4885GABRD 2754/4885GABRA1 2083/4885 |
| US-10758528-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof | OPRM1, OPRK1, OPRD1 | GABRP 60/4885GABRD 20/4885GABRA1 43/4885 |
| US-20150065536-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof | CYP2B6, CYP3A43, CYP2D6 | GABRP 330/4885GABRD 110/4885GABRA1 174/4885 |
| US-20250032479-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | OPRM1, OPRL1, OPRK1 | GABRP 287/4885GABRD 453/4885GABRA1 1119/4885 |
| US-20180338968-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | GABRP 60/4885GABRD 20/4885GABRA1 43/4885 |
| US-10654863-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | CYP3A43, CYP2B6, CYP2D6 | GABRP 185/4885GABRD 60/4885GABRA1 93/4885 |
| US-11197933-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | OPRM1, OPRK1, OPRL1 | GABRP 41/4885GABRD 242/4885GABRA1 264/4885 |
| US-20240165106-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRK1, OPRM1, CYP3A5 | GABRP 1681/4885GABRD 2754/4885GABRA1 2083/4885 |
| US-20220054479-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | GABRP 710/4885GABRD 2174/4885GABRA1 1819/4885 |
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | GABRP 710/4885GABRD 2174/4885GABRA1 1819/4885 |
| US-10544153-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxycodone, prodrugs, methods of making and use thereof | OPRM1, OPRK1, OPRD1 | GABRP 77/4885GABRD 21/4885GABRA1 32/4885 |
| US-20170312270-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | GABRP 60/4885GABRD 20/4885GABRA1 43/4885 |
| US-20160151352-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | GABRP 60/4885GABRD 20/4885GABRA1 43/4885 |
| US-20200101166-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRL1 | GABRP 41/4885GABRD 242/4885GABRA1 264/4885 |
| US-20190160175-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | CYP3A43, CYP2B6, CYP2D6 | GABRP 185/4885GABRD 60/4885GABRA1 93/4885 |
| US-20180104352-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | CYP3A43, CYP2B6, CYP2D6 | GABRP 185/4885GABRD 60/4885GABRA1 93/4885 |
| US-10463660-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof | OPRM1, OPRK1, OPRD1 | GABRP 60/4885GABRD 20/4885GABRA1 43/4885 |
| US-12076316-B2 | Levorphanol prodrugs and processes for making and using them | OPRM1, OPRL1, OPRK1 | GABRP 281/4885GABRD 448/4885GABRA1 1125/4885 |
| US-12590065-B2 | Levorphanol prodrugs and processes for making and using them | SLC16A3, SLC16A8, SLC16A1 | GABRP 162/4885GABRD 115/4885GABRA1 821/4885 |
| US-20170112825-A1 | METHODS AND COMPOSITIONS FOR REGULATING CONVERSION OF A PRODRUG TO AN ACTIVE PHARMACEUTICAL INGREDIENT | CES2, CYP2C19, CYP2C18 | GABRP 1150/4885GABRD 1905/4885GABRA1 2122/4885 |
| US-20180177883-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | CYP3A43, CYP2B6, CYP2D6 | GABRP 185/4885GABRD 60/4885GABRA1 93/4885 |
| US-20170226118-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof | CYP2B6, CYP3A43, CYP2D6 | GABRP 330/4885GABRD 110/4885GABRA1 174/4885 |
| US-20180339056-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof | OPRM1, OPRK1, CYP2D6 | GABRP 83/4885GABRD 60/4885GABRA1 64/4885 |
| US-20160168160-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | GABRP 77/4885GABRD 21/4885GABRA1 32/4885 |
| US-20250161468-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRL1 | GABRP 41/4885GABRD 242/4885GABRA1 264/4885 |
| US-20140330021-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof | OPRM1, OPRK1, CYP2D6 | GABRP 83/4885GABRD 60/4885GABRA1 64/4885 |
| US-20190192670-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, CYP2D6 | GABRP 83/4885GABRD 60/4885GABRA1 64/4885 |
| US-20170143696-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USES THEREOF | CYP2B6, CYP3A43, CYP2D6 | GABRP 330/4885GABRD 110/4885GABRA1 174/4885 |
| US-10358452-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof | CYP2B6, CYP3A43, CYP2D6 | GABRP 330/4885GABRD 110/4885GABRA1 174/4885 |
| US-20170100390-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRK1, OPRM1, CYP3A5 | GABRP 1681/4885GABRD 2754/4885GABRA1 2083/4885 |
| US-10335406-B2 | Opioid compositions resistant to overdose and abuse | OPRM1, OPRK1, OPRD1 | GABRP 710/4885GABRD 2174/4885GABRA1 1819/4885 |
| US-20180065975-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | GABRP 77/4885GABRD 21/4885GABRA1 32/4885 |
| US-20170368058-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRK1, OPRM1, CYP3A5 | GABRP 1681/4885GABRD 2754/4885GABRA1 2083/4885 |
| US-20180064820-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof | OPRM1, OPRK1, CYP2D6 | GABRP 83/4885GABRD 60/4885GABRA1 64/4885 |
| US-20160193204-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof | CYP2B6, CYP3A43, CYP2D6 | GABRP 330/4885GABRD 110/4885GABRA1 174/4885 |
| US-20150335759-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | CYP3A43, CYP2B6, CYP2D6 | GABRP 185/4885GABRD 60/4885GABRA1 93/4885 |
| US-20230241054-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRK1, OPRM1, CYP3A5 | GABRP 1681/4885GABRD 2754/4885GABRA1 2083/4885 |
| US-20210002226-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | OPRM1, OPRK1, OPRD1 | GABRP 338/4885GABRD 512/4885GABRA1 1153/4885 |
| US-11129825-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | OPRK1, OPRM1, CYP3A5 | GABRP 1681/4885GABRD 2754/4885GABRA1 2083/4885 |
| US-10577376-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof | CYP3A43, CYP2B6, CYP2D6 | GABRP 185/4885GABRD 60/4885GABRA1 93/4885 |
| US-20130252994-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof | CYP2B6, CYP3A43, CYP2D6 | GABRP 316/4885GABRD 104/4885GABRA1 167/4885 |
| US-20200030316-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | GABRP 60/4885GABRD 20/4885GABRA1 43/4885 |
| US-20160200731-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof | CYP2B6, CYP3A43, CYP2D6 | GABRP 330/4885GABRD 110/4885GABRA1 174/4885 |
| US-20190183884-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRK1, OPRM1, CYP3A5 | GABRP 1681/4885GABRD 2754/4885GABRA1 2083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.