Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY4 known ✓ | P51582 | 2/20 | 0.42 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.41 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.41 |
| ▸ | P2RY2 known ✓ | P41231 | 1/20 | 0.41 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111260 | 0.82 | P2RY12 (0.37) | TSHRMAPK1POLBALDH1A1F2 | |
| SCHEMBL2650962 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2TSHRMAPK1POLBKDM4E | |
| SCHEMBL1805768 | 0.81 | PKM (0.60) | SMN1; SMN2TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL11111261 | 0.81 | GAA (0.40) | TSHRMAPK1POLBKDM4EALDH1A1 | |
| SCHEMBL31330205 | 0.80 | RAPGEF4 (0.47) | SMN1; SMN2TSHRMAPK1POLBKDM4E | |
| SCHEMBL8904758 | 0.80 | TRPV4 (0.51) | SMN1; SMN2TSHRMAPK1POLBKDM4E | |
| SCHEMBL158166 | 0.80 | RAPGEF4 (0.47) | SMN1; SMN2TSHRMAPK1POLBKDM4E | |
| SCHEMBL9817115 | 0.79 | RAPGEF4 (0.46) | SMN1; SMN2TSHRMAPK1POLBKDM4E | |
| SCHEMBL28830227 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2TSHRMAPK1POLBKDM4E | |
| SCHEMBL10641260 | 0.77 | L3MBTL1 (0.68) | SMN1; SMN2TSHRMAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143464-A | Method for preparing organic pigment easy to disperse in plastic | 江苏乾润新材料科技有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-117143464-A | Method for preparing organic pigment easy to disperse in plastic | 江苏乾润新材料科技有限公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-0066282-B2 | HEAT-DEVELOPABLE COLOR PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |
| EP-0066282-B1 | HEAT-DEVELOPABLE COLOR PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1986-01-02 | — | — | EP | disclosed |
| US-4478927-A | SILVER HALIDE EMULSION, ORGANIC SILVER SALT, BINDER, AND DYE-RELEASING REDOX COMPOUND; PHOTOTHERMOGRAPHY; STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1984-10-23 | — | — | US | disclosed |