Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37411 | 0.81 | ENPEP (0.39) | GSTK1ENPEPFOLH1ANPEP | |
| Dihydrolipoic Acid SCHEMBL867951 | 0.81 | FOLH1 (0.56) | GSTK1ENPEPFOLH1ANPEPLMNA | |
| Dihydrolipoic Acid SCHEMBL19773 | 0.81 | FOLH1 (0.56) | GSTK1ENPEPFOLH1ANPEPLMNA | |
| Dihydrolipoic Acid SCHEMBL618576 | 0.81 | FOLH1 (0.56) | GSTK1ENPEPFOLH1ANPEPLMNA | |
| Dihydrolipoic Acid SCHEMBL1115003 | 0.81 | FOLH1 (0.56) | GSTK1ENPEPFOLH1ANPEPLMNA | |
| SCHEMBL12852188 | 0.80 | PAOX (0.38) | PAOXALDH1A1ACHEFOLH1 | |
| Dihydrolipoic Acid SCHEMBL2578740 | 0.79 | FOLH1 (0.54) | GSTK1ENPEPFOLH1ANPEPLMNA | |
| SCHEMBL6809842 | 0.79 | GSTK1 (0.57) | ALDH1A1GSTK1ENPEPFOLH1ANPEP | |
| SCHEMBL2576303 | 0.79 | ENPEP (0.38) | GSTK1ENPEPFOLH1ANPEP | |
| SCHEMBL21611884 | 0.79 | GSTK1 (0.57) | ALDH1A1GSTK1ENPEPFOLH1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170168042-A1 | CONTROLLING THE ARCHITECTURE, COORDINATION, AND REACTIVITY OF NANOPARTICLE COATING UTILIZING AN AMINO ACID CENTRAL SCAFFOLD | The Florida State University Research Foundation, Inc. | 2017-06-15 | — | — | US | disclosed |
| US-9304124-B2 | Compact multifunctional ligand to enhance colloidal stability of nanoparticles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2016-04-05 | — | — | US | disclosed |
| US-9304124-B2 | Compact multifunctional ligand to enhance colloidal stability of nanoparticles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2016-04-05 | — | — | US | disclosed |
| US-9125940-B2 | Compositions and methods for treating macular edema | MA ZHUNING (US) | 2015-09-08 | — | — | US | disclosed |
| US-8586625-B2 | Derivatives of taxol and closely related compounds | RAYAN ANWAR (IL) | 2013-11-19 | — | — | US | disclosed |
| US-8586625-B2 | Derivatives of taxol and closely related compounds | RAYAN ANWAR (IL) | 2013-11-19 | — | — | US | disclosed |
| US-20130296390-A1 | METHOD AND COMPOSITIONS FOR ENHANCING THE SAFETY OF ORALLY ADMINISTERED MAGNESIUM ALPHA-LIPOATE | BIOLINK LIFE SCIENCES, INC. (US) | 2013-11-07 | — | — | US | disclosed |
| US-8512755-B2 | Compact multifunctional ligand to enhance colloidal stability of nanoparticles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-08-20 | — | — | US | disclosed |
| US-8512755-B2 | Compact multifunctional ligand to enhance colloidal stability of nanoparticles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-08-20 | — | — | US | disclosed |
| US-20130157986-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | INVASC THERAPEUTICS, INC. (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2013025347-A1 | COMPACT MULTIFUNCTIONAL LIGAND TO ENHANCE COLLOIDAL STABILITY OF NANOPARTICLES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-02-21 | — | — | WO | disclosed |
| US-20120201830-A1 | COMPOSITIONS AND METHODS FOR TREATING MACULAR EDEMA | Micha Advanced Health | 2012-08-09 | — | — | US | disclosed |
| US-8198317-B2 | Methylenedioxy phenolic compounds and their use to treat disease | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-12 | — | — | US | disclosed |
| US-20110038955-A1 | PREVENTION OF GASTRIC ULCER BY CARBON MONOXIDE | ALFAMA - INVESTIGACAO E DESENVOLVIMENTO DE PRODUTOS FARMACEUTICOS, LDA. (PT) | 2011-02-17 | — | — | US | disclosed |
| US-20100311080-A1 | WATER-SOLUBLE NANOCRYSTALS THROUGH DUAL-INTERACTION LIGANDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100298421-A1 | DERIVATIVES OF TAXOL AND CLOSELY RELATED COMPOUNDS | RAYAN ANWAR | 2010-11-25 | — | — | US | disclosed |
| US-20100298421-A1 | DERIVATIVES OF TAXOL AND CLOSELY RELATED COMPOUNDS | RAYAN ANWAR | 2010-11-25 | — | — | US | disclosed |
| US-20100035849-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-02-11 | — | — | US | disclosed |
| WO-2009090614-A2 | DERIVATIVES OF TAXOL AND CLOSELY RELATED COMPOUNDS | RAYAN ANWAR (IL) | 2009-07-23 | — | — | WO | disclosed |
| US-7220818-B2 | Noncovalent functionalization of nanotubes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298421-A1 | DERIVATIVES OF TAXOL AND CLOSELY RELATED COMPOUNDS | TBCA, TUBA1C, TUBB6 | PAOX 936/4885ALDH1A1 920/4885ACHE 3481/4885 |
| US-20120201830-A1 | COMPOSITIONS AND METHODS FOR TREATING MACULAR EDEMA | ALOX15B, ALOX15, ALOX12 | PAOX 18/4885ALDH1A1 1972/4885ACHE 4376/4885 |
| US-20130296390-A1 | METHOD AND COMPOSITIONS FOR ENHANCING THE SAFETY OF ORALLY ADMINISTERED MAGNESIUM ALPHA-LIPOATE | HLCS, LIPA, PROC | PAOX 1297/4885ALDH1A1 2312/4885ACHE 2085/4885 |
| US-20110038955-A1 | PREVENTION OF GASTRIC ULCER BY CARBON MONOXIDE | PTGS1, PTGS2, NOS2 | PAOX 1884/4885ALDH1A1 487/4885ACHE 3428/4885 |
| US-20100035849-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | REN, PCSK9, ALOX12 | PAOX 308/4885ALDH1A1 787/4885ACHE 2080/4885 |
| US-20170168042-A1 | CONTROLLING THE ARCHITECTURE, COORDINATION, AND REACTIVITY OF NANOPARTICLE COATING UTILIZING AN AMINO ACID CENTRAL SCAFFOLD | CLTA, ALAD, PELP1 | PAOX 3534/4885ALDH1A1 1706/4885ACHE 2090/4885 |
| US-20130157986-A1 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE | REN, PCSK9, COMT | PAOX 195/4885ALDH1A1 773/4885ACHE 1245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.