Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
| ▸ | GGH | Q92820 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13475050 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNASLC15A2ANPEPENPEP | |
| SCHEMBL16250326 | 0.88 | NOD1 (0.39) | ALDH1A1 | |
| SCHEMBL16250328 | 0.88 | NOD1 (0.39) | ALDH1A1 | |
| SCHEMBL20813347 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNASLC15A2ANPEPENPEP | |
| SCHEMBL12157036 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNASLC15A2ANPEPENPEP | |
| SCHEMBL24658500 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNASLC15A2ANPEPENPEP | |
| SCHEMBL23627350 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNASLC15A2ANPEPENPEP | |
| SCHEMBL8290794 | 0.84 | ANPEP (0.50) | ANPEPENPEPFOLH1RIMKLANAALAD2 | |
| SCHEMBL6888354 | 0.84 | ANPEP (0.50) | ANPEPENPEPFOLH1RIMKLANAALAD2 | |
| SCHEMBL22111315 | 0.84 | FOLH1 (0.43) | ALDH1A1LMNASLC15A2ANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793881-B2 | Polyethylene glycol conjugate medicament, preparation method therefor and use thereof | Chongqing Upgra Biotechnology Co., Ltd. (CN) | 2023-10-24 | — | — | US | disclosed |
| US-11793881-B2 | Polyethylene glycol conjugate medicament, preparation method therefor and use thereof | Chongqing Upgra Biotechnology Co., Ltd. (CN) | 2023-10-24 | — | — | US | disclosed |
| EP-4230205-A1 | ANTITUMOR PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Jenkem Technology Co. Ltd. (Tianjin) (CN) | 2023-08-23 | — | — | EP | disclosed |
| EP-4227300-A1 | TRUNCATED EVANS BLUE MODIFIED FIBROBLAST ACTIVATION PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Yantai Lannacheng Biotechnology Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| WO-2023150149-A1 | IMPROVED SOPHOROLIPID DERIVATIVES WITH THERAPEUTIC AGENT CARGOS AND THEIR USE | LOCUS SOLUTIONS IPCO, LLC (US) | 2023-08-10 | — | — | WO | disclosed |
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | TECHFIELDS PHARMA CO., LTD (CN) | 2023-07-27 | — | — | US | disclosed |
| EP-4194553-A1 | MODIFIED SIRNA WITH REDUCED OFF-TARGET ACTIVITY | Tuojie Biotech (Shanghai) Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| EP-4190361-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG, AND PREPARATION METHOD THERFOR AND USE THEREOF | Chongqing Upgra Biotechnology Co., Ltd. (CN) | 2023-06-07 | — | — | EP | disclosed |
| US-20230036997-A1 | COMBINATION OF POLYETHYLENE GLYCOL AND RAPAMYCIN AND USE THEREOF | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-02-02 | — | — | US | disclosed |
| WO-2022022360-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG, AND PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2022-02-03 | — | — | WO | disclosed |
| US-20100233190-A1 | TARGETED POLYMERIC PRODRUGS CONTAINING MULTIFUNCTIONAL LINKERS | ENZON PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100098653-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | CEDARS-SINAI MEDICAL CENTER (US) | 2010-04-22 | — | — | US | disclosed |
| US-20100093935-A1 | METHOD OF PREPARING POLYGLUTAMATE CONJUGATES | NITTO DENKO CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20100028416-A1 | DRUG CARRIERS | NITTO DENKO CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20080279782-A1 | POLYMERS CONJUGATED WITH PLATINUM DRUGS | NITTO DENKO CORPORATION (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080279777-A1 | COMPOSITIONS THAT INCLUDE A HYDROPHOBIC COMPOUND AND A POLYAMINO ACID CONJUGATE | NITTO DENKO CORPORATION (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080253969-A1 | MULTI-FUNCTIONAL POLYGLUTAMATE DRUG CARRIERS | NITTO DENKO CORPORATION (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080213175-A1 | Click chemistry-derived cyclic peptidomimetics as integrin markers | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2008-09-04 | — | — | US | disclosed |
| US-20080181852-A1 | Multi-functional Drug Carriers | NITTO DENKO CORPORATION (JP) | 2008-07-31 | — | — | US | disclosed |
| US-20070128118-A1 | POLYGLUTAMATE-AMINO ACID CONJUGATES AND METHODS | NITTO DENKO CORPORATION (JP) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233190-A1 | TARGETED POLYMERIC PRODRUGS CONTAINING MULTIFUNCTIONAL LINKERS | PAICS, FCGRT, DNPEP | ALDH1A1 959/4885LMNA 2811/4885SLC15A2 1247/4885 |
| US-20080213175-A1 | Click chemistry-derived cyclic peptidomimetics as integrin markers | ITGB1, ITGAM, ITGB3 | ALDH1A1 2416/4885LMNA 4150/4885SLC15A2 2241/4885 |
| US-20080253969-A1 | MULTI-FUNCTIONAL POLYGLUTAMATE DRUG CARRIERS | CD44, SGTA, IDUA | ALDH1A1 2483/4885LMNA 3393/4885SLC15A2 45/4885 |
| US-20230036997-A1 | COMBINATION OF POLYETHYLENE GLYCOL AND RAPAMYCIN AND USE THEREOF | RICTOR, MTOR, ICOS | ALDH1A1 4612/4885LMNA 4811/4885SLC15A2 2538/4885 |
| US-20100028416-A1 | DRUG CARRIERS | HDGF, FIBP, HAVCR2 | ALDH1A1 851/4885LMNA 2139/4885SLC15A2 201/4885 |
| US-11793881-B2 | Polyethylene glycol conjugate medicament, preparation method therefor and use thereof | SLC10A1, SLC10A2, NOTUM | ALDH1A1 1580/4885LMNA 2899/4885SLC15A2 514/4885 |
| US-20100098653-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | GPX1, GPX4, LPO | ALDH1A1 172/4885LMNA 3189/4885SLC15A2 1367/4885 |
| US-20070128118-A1 | POLYGLUTAMATE-AMINO ACID CONJUGATES AND METHODS | FOLH1, SLC7A1, SLC3A2 | ALDH1A1 2758/4885LMNA 3030/4885SLC15A2 69/4885 |
| US-20080181852-A1 | Multi-functional Drug Carriers | SLC7A1, SLC19A1, SLC43A1 | ALDH1A1 2799/4885LMNA 3455/4885SLC15A2 39/4885 |
| US-20080279777-A1 | COMPOSITIONS THAT INCLUDE A HYDROPHOBIC COMPOUND AND A POLYAMINO ACID CONJUGATE | SLC7A1, MSN, CD44 | ALDH1A1 3366/4885LMNA 501/4885SLC15A2 278/4885 |
| US-20080279782-A1 | POLYMERS CONJUGATED WITH PLATINUM DRUGS | FOLR1, PAICS, ABCC1 | ALDH1A1 1324/4885LMNA 3456/4885SLC15A2 250/4885 |
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | SLC5A7, SLC19A1, SLC43A1 | ALDH1A1 2302/4885LMNA 2635/4885SLC15A2 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.