Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087097 | 0.75 | TDP1 (0.60) | ALOX15TDP1TYMSALDH1A1 | |
| SCHEMBL31548711 | 0.75 | TDP1 (0.60) | ALOX15TDP1TYMSALDH1A1 | |
| Dimethyl Sulfoxide SCHEMBL28038423 | 0.72 | MAOA (0.47) | ALOX15TDP1TYMSALDH1A1 | |
| SCHEMBL30073249 | 0.71 | TDP1 (0.48) | ALOX15TDP1TYMSALDH1A1 | |
| SCHEMBL29539686 | 0.70 | ALOX15 (0.52) | ALOX15TDP1TYMSALDH1A1 | |
| SCHEMBL31416073 | 0.70 | TDP1 (0.52) | ALOX15TDP1TYMSALDH1A1 | |
| SCHEMBL19604974 | 0.70 | TDP1 (0.52) | ALOX15TDP1TYMSALDH1A1 | |
| SCHEMBL10502400 | 0.70 | TDP1 (0.52) | ALOX15TDP1TYMSALDH1A1 | |
| SCHEMBL166198 | 0.70 | ALOX15 (0.52) | ALOX15TDP1TYMSALDH1A1 | |
| SCHEMBL308375 | 0.70 | TDP1 (0.52) | ALOX15TDP1TYMSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863463-B2 | Method of purifying dianhydrides | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-01-04 | — | — | US | claimed |
| US-7495113-B2 | Method of purifying dianhydrides | SABIC INNOVATIVE PLASTICS (US) | 2009-02-24 | — | — | US | claimed |
| US-20070117990-A1 | Method of purifying dianhydrides | GENERAL ELECTRIC COMPANY (US) | 2007-05-24 | — | — | US | claimed |
| US-20060135791-A1 | Method of purifying dianhydrides | GENERAL ELECTRIC COMPANY | 2006-06-22 | — | — | US | claimed |
| US-7981996-B2 | reaction of a diamine such as ortho, meta or para-phenylenediamine with an anhydride like 3- or 4-chlorophthalic anhydride (3-ClPA) in the presence of a solvent (ortho dichlorobenzene) at a temperature above the normal boiling point of the solvent to produce bis/halophthalobisimide/; limited solubility | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-07-19 | — | — | US | disclosed |
| EP-1674443-B1 | Method of purifying dianhydrides | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-07-29 | — | — | EP | disclosed |
| US-7495113-B2 | Method of purifying dianhydrides | SABIC INNOVATIVE PLASTICS (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080119660-A1 | reaction of a diamine such as ortho, meta or para-phenylenediamine with an anhydride like 3- or 4-chlorophthalic anhydride (3-ClPA) in the presence of a solvent (ortho dichlorobenzene) at a temperature above the normal boiling point of the solvent to produce bis/halophthalobisimide/; limited solubility | GENERAL ELECTRIC COMPANY (US) | 2008-05-22 | — | — | US | disclosed |
| EP-1674443-A1 | Method of purifying dianhydrides | The General Electric Company (US) | 2006-06-28 | — | — | EP | disclosed |
| US-20060135791-A1 | Method of purifying dianhydrides | GENERAL ELECTRIC COMPANY | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119660-A1 | reaction of a diamine such as ortho, meta or para-phenylenediamine with an anhydride like 3- or 4-chlorophthalic anhydride (3-ClPA) in the presence of a solvent (ortho dichlorobenzene) at a temperature above the normal boiling point of the solvent to produce bis/halophthalobisimide/; limited solubility | DDT, DDC, DDAH1 | ALOX15 2718/4885TDP1 279/4885TYMS 2091/4885 |
| US-20070117990-A1 | Method of purifying dianhydrides | CA7, HDHD5, CA2 | ALOX15 4790/4885TDP1 1591/4885TYMS 3734/4885 |
| US-20060135791-A1 | Method of purifying dianhydrides | SAMHD1, TREH, DOHH | ALOX15 4090/4885TDP1 2169/4885TYMS 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.