Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | GLB1 | P16278 | 1/20 | 0.50 |
| ▸ | CHAT | P28329 | 1/20 | 0.50 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110711 | 1.00 | THRB (0.71) | THRBALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL29382053 | 1.00 | THRB (0.71) | THRBALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL4841813 | 0.94 | THRB (0.67) | THRBALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL3188346 | 0.94 | THRB (0.67) | THRBALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL29382082 | 0.87 | THRB (0.74) | THRBALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL1136824 | 0.84 | BRD4 (0.62) | THRBALDH1A1HPGDALOX12RECQL | |
| SCHEMBL692673 | 0.84 | BRD4 (0.62) | THRBALDH1A1HPGDALOX12RECQL | |
| SCHEMBL6126114 | 0.84 | BRD4 (0.62) | THRBALDH1A1HPGDALOX12RECQL | |
| E122 SCHEMBL29360316 | 0.83 | THRB (1.00) | THRBALDH1A1CYP3A4HPGDALOX15 | |
| E122 SCHEMBL2833594 | 0.83 | THRB (1.00) | THRBALDH1A1CYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 807 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114388077-A | Traditional Chinese medicine dyed material database based on micro-focusing Raman technology and application thereof in identification of traditional Chinese medicine dyed materials | 成都市食品药品检验研究院 | 2022-04-22 | — | — | CN | claimed |
| WO-2021104729-A1 | BIODEGRADABLE BEADS WITH DYES AND PIGMENTS | BASF SE (DE) | 2021-06-03 | — | — | WO | claimed |
| EP-3827806-A1 | BIODEGRADABLE BEADS WITH DYES AND PIGMENTS | BASF SE (DE) | 2021-06-02 | — | — | EP | claimed |
| US-20200400663-A1 | SILICA NANOPARTICLES FOR BIOMARKER DIAGNOSIS AND METHOD FOR PRODUCING SAME | DXGEN CORP. (KR) | 2020-12-24 | — | — | US | claimed |
| EP-3726215-A1 | SILICA NANOPARTICLES FOR BIOMARKER DIAGNOSIS AND METHOD FOR PRODUCING SAME | DxGen Corp. (KR) | 2020-10-21 | — | — | EP | claimed |
| EP-2930126-B1 | Fashionable aerosol dye | HENKEL AG & CO KGAA (DE) | 2019-10-09 | — | — | EP | claimed |
| WO-2019117586-A1 | SILICA NANOPARTICLES FOR BIOMARKER DIAGNOSIS AND METHOD FOR PRODUCING SAME | 주식회사 딕스젠 | 2019-06-20 | — | — | WO | claimed |
| US-9296901-B2 | Composite particles, and coloring composition and resin composition using the same | TODA KOGYO CORPORATION (JP) | 2016-03-29 | — | — | US | claimed |
| US-20150079008-A1 | FLUORESCENCE PLAQUE-DISCLOSANT FOR DETECTING DENTAL PLAQUE | FLOSS MY HEART, LLC | 2015-03-19 | — | — | US | claimed |
| EP-2544723-A2 | COMPOSITIONS FOR COLON LAVAGE AND METHODS OF MAKING AND USING SAME | Giuliani International Limited (IE) | 2013-01-16 | — | — | EP | claimed |
| WO-2011110347-A2 | COMPOSITIONS FOR COLON LAVAGE AND METHODS OF MAKING AND USING SAME | GIULIANI INTERNATIONAL LIMITED (IE) | 2011-09-15 | — | — | WO | claimed |
| US-20100081728-A1 | Mixable and color tone freely reproducible dental coloring material composition, and set and method thereof | KABUSHIKI KAISHA SHOFU | 2010-04-01 | — | — | US | claimed |
| WO-2004004685-A1 | MEDICINAL SUSPENSION AEROSOL MODEL SYSTEMS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-01-15 | — | — | WO | claimed |
| EP-0533937-B1 | ACIDIC HAIR DYE COMPOSITION | SHISEIDO CO LTD (JP) | 1997-05-14 | — | — | EP | claimed |
| US-20260124128-A1 | COMPOSITION COMPRISING LARGE AMOUNT OF POLYOL | L'OREAL (FR) | 2026-05-07 | — | — | US | disclosed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | disclosed |
| US-12616695-B2 | Use of 5-amino-2,3-dihydro-1,4-phthalazinedione in the treatment of rare chronic inflammatory pulmonary diseases | METRIOPHARM AG (CH) | 2026-05-05 | — | — | US | disclosed |
| US-4855133-A | Composition for attracting flies | EARTH CHEMICAL COMPANY, LIMITED (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0229191-A1 | FLY-ATTRACTIVE COMPOSITION | EARTH CHEMICAL CO., LTD. (JP) | 1987-07-22 | — | — | EP | disclosed |
| US-3966922-A | TETRACYCLINE, VITAMIN B(2), VANILLIN | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124128-A1 | COMPOSITION COMPRISING LARGE AMOUNT OF POLYOL | GK, PRKG2, PRKG1 | THRB 2784/4885ALDH1A1 2331/4885CYP3A4 4871/4885 |
| US-12616695-B2 | Use of 5-amino-2,3-dihydro-1,4-phthalazinedione in the treatment of rare chronic inflammatory pulmonary diseases | CRYZ, PDE12, FKBP5 | THRB 4196/4885ALDH1A1 515/4885CYP3A4 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.