Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | KMO | O15229 | 1/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.60 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.60 |
| ▸ | HTR3B | O95264 | 3/20 | 0.60 |
| ▸ | HTR3A | P46098 | 3/20 | 0.60 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.60 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | HTR2C | P28335 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | HTR6 | P50406 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30966888 | 1.00 | ALDH1A1 (0.73) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL31349273 | 0.98 | ALDH1A1 (0.71) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL30444622 | 0.98 | ALDH1A1 (0.71) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL31107600 | 0.87 | ADRB1 (0.60) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL3868910 | 0.87 | ADRB1 (0.60) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| Phenylpiperazine SCHEMBL3424663 | 0.86 | ALDH1A1 (0.73) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL3072477 | 0.85 | ADRB1 (0.58) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6503848 | 0.85 | ADRB1 (0.58) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL3453744 | 0.85 | ADRB1 (0.58) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL1517203 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| US-10253006-B2 | Assay for the detection of the phenylpiperazine family | RANDOX LABORATORIES LIMITED (GB) | 2019-04-09 | — | — | US | claimed |
| US-20160229824-A1 | ASSAY FOR THE DETECTION OF THE PHENYLPIPERAZINE FAMILY | NORTHERN BANK LIMITED (IE) | 2016-08-11 | — | — | US | claimed |
| EP-2631231-B1 | Assay for the detection of the phenypiperazine family | RANDOX LAB LTD (GB) | 2016-04-20 | — | — | EP | claimed |
| US-20130224882-A1 | Assay for the Detection of the Phenylpiperazine Family | RANDOX LABORATORIES LIMITED (GB) | 2013-08-29 | — | — | US | claimed |
| EP-2631231-A1 | Assay for the detection of the phenypiperazine family | Randox Laboratories Ltd. (GB) | 2013-08-28 | — | — | EP | claimed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| US-20210300936-A1 | PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST | BEONE MEDICINES I GMBH (CH) | 2021-09-30 | — | — | US | disclosed |
| US-20210300936-A1 | PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST | BEONE MEDICINES I GMBH (CH) | 2021-09-30 | — | — | US | disclosed |
| CN-112469722-A | Pyrazolo-triazolopyrimidine derivatives as A2A receptor antagonists | 百济神州有限公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-106928204-B | Piperazine derivative, preparation method and application thereof | 牡丹江医学院 | 2020-03-03 | — | — | CN | disclosed |
| WO-2020020097-A1 | PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST | BEIGENE, LTD. (KY) | 2020-01-30 | — | — | WO | disclosed |
| US-10407422-B2 | Triazolopyridine inhibitors of myeloperoxidase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-10 | — | — | US | disclosed |
| US-7208495-B2 | Benzo-fused 5-membered hetrocycle compounds, process for preparation of the same, and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-04-24 | — | — | US | disclosed |
| WO-2006111549-A1 | DIHYDROTHIENOPYRIMIDINES FOR THE TREATMENT OF INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-10-26 | — | — | WO | disclosed |
| US-7030120-B2 | Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AVENTIS PHARMA S. A. (FR) | 2005-06-16 | — | — | US | disclosed |
| US-20040224959-A1 | Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same | OHKURA NAOTO (JP) | 2004-11-11 | — | — | US | disclosed |
| US-6777414-B1 | INHIBITORS OF TRIGLYCERIDE BIOSYNTHESIS AND SECRETION OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; ARTERIOSCLEROTIC DISEASES; HYPERLIPIDEMIA | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| EP-1180514-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND BENAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2002-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300936-A1 | PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST | ADORA2A, ADORA3, ADORA2B | ALDH1A1 1114/4885HSD17B10 4479/4885HPGD 1646/4885 |
| US-20130224882-A1 | Assay for the Detection of the Phenylpiperazine Family | METAP2, DCPS, NPEPPS | ALDH1A1 4387/4885HSD17B10 4343/4885HPGD 1042/4885 |
| US-20040224959-A1 | Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same | APOB, NCEH1, LIPC | ALDH1A1 1345/4885HSD17B10 345/4885HPGD 775/4885 |
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AHR, NQO1, ARNT | ALDH1A1 360/4885HSD17B10 618/4885HPGD 194/4885 |
| US-10407422-B2 | Triazolopyridine inhibitors of myeloperoxidase | EPX, MPO, SERPINB1 | ALDH1A1 83/4885HSD17B10 1991/4885HPGD 164/4885 |
| US-10253006-B2 | Assay for the detection of the phenylpiperazine family | METAP2, DCPS, NPEPPS | ALDH1A1 4387/4885HSD17B10 4343/4885HPGD 1042/4885 |
| US-20160229824-A1 | ASSAY FOR THE DETECTION OF THE PHENYLPIPERAZINE FAMILY | METAP2, DCPS, NPEPPS | ALDH1A1 4387/4885HSD17B10 4343/4885HPGD 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.