Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10816359 | 0.76 | LTA4H (0.45) | SLC6A4LTA4HTSHRL3MBTL1SRC | |
| SCHEMBL3485914 | 0.75 | SLC6A4 (0.41) | SLC6A4SRD5A2CES2CES1LTA4H | |
| SCHEMBL9859672 | 0.74 | SRD5A2 (0.57) | SLC6A4SRD5A2LTA4HTSHRSCN4A | |
| SCHEMBL28636911 | 0.74 | SLC6A4 (0.44) | SLC6A4SRD5A2LTA4HTSHRSCN4A | |
| SCHEMBL7564026 | 0.74 | SLC6A4 (0.44) | SLC6A4SRD5A2LTA4HTSHRSCN4A | |
| SCHEMBL9654028 | 0.73 | SLC6A2 (0.46) | SLC6A4ADRA2AADRA2BADRA2CMEN1 | |
| SCHEMBL57754 | 0.72 | MTNR1A (0.46) | LTA4HTSHRADRA2AADRA2BADRA2C | |
| SCHEMBL83160 | 0.72 | KMT2A (0.46) | CES2CES1TSHRCYP2D6SRC | |
| SCHEMBL4022188 | 0.72 | CES2 (0.46) | CES2CES1L3MBTL1CYP2D6SRC | |
| SCHEMBL10611867 | 0.72 | LTA4H (0.41) | SLC6A4LTA4HTSHRL3MBTL1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150219676-A1 | BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL | VERSITECH LIMITED (CN) | 2015-08-06 | — | — | US | claimed |
| US-8217041-B2 | Indene derivatives, their preparation and use as medicaments | Laboratories del Sr. Esteve, S.A. (ES) | 2012-07-10 | — | — | US | claimed |
| EP-2202222-A2 | Indene derivatives, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-06-30 | — | — | EP | claimed |
| US-20090264457-A1 | Combination of at least two 5HT6-Ligands | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-10-22 | — | — | US | claimed |
| US-20090163547-A1 | INDENE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-06-25 | — | — | US | claimed |
| EP-2020230-A1 | Combination of at least two 5-HT6-Ligands | Laboratorios del Dr. Esteve S.A. (ES) | 2009-02-04 | — | — | EP | claimed |
| EP-1960343-A2 | INDENE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | Laboratorios del Dr. Esteve S.A. (ES) | 2008-08-27 | — | — | EP | claimed |
| WO-2007054257-A2 | INDENE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-18 | — | — | WO | claimed |
| EP-1699779-A1 | 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF | AstraZeneca AB (SE) | 2006-09-13 | — | — | EP | claimed |
| WO-2005061484-A1 | 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF | ASTRAZENECA AB (SE) | 2005-07-07 | — | — | WO | claimed |
| US-5859020-A | INSECTICIDES, MITICIDES, FUNGICIDES, NEMATOCIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1999-01-12 | — | — | US | claimed |
| US-4810717-A | ADRENERGIC BLOCKING AGENTS, GLAUCOMA | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-07 | — | — | US | claimed |
| EP-0179807-A4 | STABLE PHARMACEUTICAL COMPOSITIONS OF SHORT-ACTING BETA-ADRENERGIC RECEPTOR BLOCKING AGENTS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1987-10-27 | — | — | EP | claimed |
| EP-0179807-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF SHORT-ACTING BETA-ADRENERGIC RECEPTOR BLOCKING AGENTS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1986-05-07 | — | — | EP | claimed |
| US-4582855-A | Aromatic and esters of hydroxypropylamines | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1986-04-15 | — | — | US | claimed |
| WO-1985004581-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF SHORT-ACTING BETA-ADRENERGIC RECEPTOR BLOCKING AGENTS | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1985-10-24 | — | — | WO | claimed |
| EP-0093765-A4 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-04-27 | — | — | EP | claimed |
| EP-0093765-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-11-16 | — | — | EP | claimed |
| WO-1983001770-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-05-26 | — | — | WO | claimed |
| US-4201780-A | Mono-5-substituted-3-chloro-4H-1,2,6-thiadiazin-4-one antifungal agents | FMC CORPORATION (US) | 1980-05-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264457-A1 | Combination of at least two 5HT6-Ligands | HTR6, HTR3B, HTR4 | SLC6A4 14/4885SRD5A2 3016/4885CES2 301/4885 |
| US-20150219676-A1 | BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL | SQOR, MT-ND4, COX6A1 | SLC6A4 706/4885SRD5A2 1833/4885CES2 1683/4885 |
| US-20090163547-A1 | INDENE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | HTR6, HTR5A, HTR1A | SLC6A4 54/4885SRD5A2 714/4885CES2 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.