Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 6/20 | 0.35 |
| ▸ | ADK | P55263 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680834 | 0.84 | PDE10A (0.39) | PDE10AMAPTSMN1; SMN2TRPV3 | |
| SCHEMBL13680848 | 0.83 | ADK (0.40) | APPADKSYKMAPT | |
| SCHEMBL3854280 | 0.82 | MEN1 (0.50) | PDE10ATRPV3 | |
| SCHEMBL13680837 | 0.81 | ALDH1A1 (0.40) | — | |
| SCHEMBL13680815 | 0.80 | PDE10A (0.46) | PDE10APARP1MAPTSMN1; SMN2 | |
| SCHEMBL13680825 | 0.80 | MAPT (0.41) | PDE10AMAPTSMN1; SMN2TRPV3 | |
| SCHEMBL13680842 | 0.78 | RAB9A (0.45) | MAPTSMN1; SMN2 | |
| SCHEMBL13680841 | 0.78 | TSHR (0.40) | AOC3 | |
| SCHEMBL13680847 | 0.77 | PDE10A (0.43) | PDE10ACYP2A6TRPV3 | |
| SCHEMBL13680830 | 0.77 | RARA (0.44) | PDE10ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |