SCHEMBL145806

SCHEMBL145806

[CH2]Cc1ccc(-c2ccc(F)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.52
IDO1 P14902 3/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
TAAR1 Q96RJ0 4/20 0.42
PYCR1 P32322 1/20 0.41
AGXT P21549 3/20 0.41
BCL2L1 Q07817 1/20 0.39
BAD Q92934 1/20 0.39
TRPA1 O75762 1/20 0.39
GAA P10253 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
PTPN1 P18031 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131868 0.92
SCHEMBL27493237 0.89 IDO1 (0.50) MAOBIDO1LOXL2TAAR1AGXT
SCHEMBL27841176 0.82 IDO1 (0.44) MAOBIDO1LOXL2TAAR1AGXT
SCHEMBL6626055 0.80 MAOB (0.59) MAOBIDO1LOXL2TAAR1PYCR1
SCHEMBL9106789 0.78 LTA4H (0.46) MAOBIDO1LOXL2AGXT
SCHEMBL27882665 0.78 TAAR1 (0.69) TAAR1AGXTPTPN1
SCHEMBL19993270 0.78 MAOB (0.56) MAOBIDO1LOXL2TAAR1PYCR1
SCHEMBL1803971 0.76 ESR1 (0.32) LOXL2HRH3
SCHEMBL10337645 0.76 BCL2L1 (0.55) MAOBIDO1LOXL2BCL2L1BAD
SCHEMBL12562793 0.76 BCL2L1 (0.55) MAOBIDO1LOXL2BCL2L1BAD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2532663-B1 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2016-03-16 EP claimed
EP-2532663-A1 Naphthalenecarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2012-12-12 EP claimed
EP-4210706-A1 METHODS FOR TREATING METASTASIS WITH CATHEPSIN C INHIBITORS Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences (CN) 2023-07-19 EP disclosed
US-20170174676-A1 CHLORINATED NAPTHALENETETRACARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2017-06-22 US disclosed
CN-103874742-B Carbazolocarbazole-bis (dicarboximides) and their use as semiconductors 巴斯夫欧洲公司 2016-08-17 CN disclosed
EP-2532663-B1 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2016-03-16 EP disclosed
CN-104919613-A Delta-olefin oligomers and polymers and their use as hole-conducting materials BASF SE 2015-09-16 CN disclosed
US-20150179954-A1 SUBSTITUTED TERRYLENE AND QUATERRYLENE DERIVATES AND USE AS SEMICONDUCTORS THEREOF BASF SE (DE) 2015-06-25 US disclosed
US-20140155603-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2014-06-05 US disclosed
US-8674104-B2 Halogen-containing perylenetetracarboxylic acid derivatives and the use thereof BASF SE (DE) 2014-03-18 US disclosed
US-8592806-B2 Quinone compounds as dopants in organic electronics NOVALED AG (DE) 2013-11-26 US disclosed
US-20110308592-A1 USE OF SUBSTITUTED PERYLENES IN ORGANIC SOLAR CELLS BASF SE (DE) 2011-12-22 US disclosed
US-20110203649-A1 USE OF INDANTHRENE COMPOUNDS IN ORGANIC PHOTOVOLTAICS BASF SE (DE) 2011-08-25 US disclosed
WO-2011101810-A1 USE OF INDANTHRENE COMPOUNDS IN ORGANIC PHOTOVOLTAICS BASF SE (DE) 2011-08-25 WO disclosed
US-20110068328-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2011-03-24 US disclosed
CN-101485007-A Method for producing organic field-effect transistors BASF SE (DE) 2009-07-15 CN disclosed
US-20090166614-A1 FLUORINATED RYLENETETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 2009-07-02 US disclosed
US-20080300405-A1 Naphthalenetetracarboxylic Aicd Derivatives and their Use as Semiconductors BASF SE (DE) 2008-12-04 US disclosed
EP-1966206-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2008-09-10 EP disclosed
WO-2007074137-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2007-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110203649-A1 USE OF INDANTHRENE COMPOUNDS IN ORGANIC PHOTOVOLTAICS ICMT, EPCAM, INF2 MAOB 3843/4885IDO1 97/4885LOXL2 1977/4885
US-20110068328-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF NR0B1, NR0B2, RXRB MAOB 1320/4885IDO1 2901/4885LOXL2 2058/4885
US-20170174676-A1 CHLORINATED NAPTHALENETETRACARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN ORGANIC ELECTRONICS SLCO2A1, SLCO2B1, SLC43A3 MAOB 967/4885IDO1 2877/4885LOXL2 2869/4885
US-20110308592-A1 USE OF SUBSTITUTED PERYLENES IN ORGANIC SOLAR CELLS PPOX, JUP, CRY2 MAOB 3503/4885IDO1 2279/4885LOXL2 1337/4885
US-20080300405-A1 Naphthalenetetracarboxylic Aicd Derivatives and their Use as Semiconductors ADSL, ALAD, EED MAOB 3091/4885IDO1 601/4885LOXL2 3780/4885
US-20150179954-A1 SUBSTITUTED TERRYLENE AND QUATERRYLENE DERIVATES AND USE AS SEMICONDUCTORS THEREOF TST, CD99, TPST2 MAOB 446/4885IDO1 293/4885LOXL2 1928/4885
US-20090166614-A1 FLUORINATED RYLENETETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF FXR2, FXR1, FTO MAOB 1895/4885IDO1 1868/4885LOXL2 3175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.