SCHEMBL1479937

SCHEMBL1479937

OB(O)c1cncc(Br)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.38
HTT P42858 4/20 0.37
ALOX15 P16050 1/20 0.37
RAB9A P51151 1/20 0.35
CYP2A6 P11509 1/20 0.34
PTK2 Q05397 1/20 0.33
EGFR P00533 1/20 0.33
ROCK2 O75116 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
ALOX12 P18054 1/20 0.33
ROCK1 Q13464 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP11B1 P15538 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28967087 0.82 ENPP2 (0.36) CA1CA2TSHRKDM4EALDH1A1
SCHEMBL27969 0.73 HCAR2 (0.45) HCAR2CYP11B1CYP11B2
SCHEMBL29957005 0.73 ENPP2 (0.44) POLBKDM4EGAACYP11B1CYP11B2
SCHEMBL29538949 0.73 HCAR2 (0.45) HCAR2CYP11B1CYP11B2
SCHEMBL13651757 0.73 ENPP2 (0.44) POLBKDM4EGAACYP11B1CYP11B2
SCHEMBL4974 0.73
SCHEMBL144194 0.71 HCAR2 (0.43) HCAR2CA2CYP2A6
SCHEMBL315514 0.71 HCAR2 (0.43) HCAR2
SCHEMBL30941538 0.71 HCAR2 (0.43) HCAR2CA2CYP2A6
Hydrochloric Acid SCHEMBL16899234 0.71 ENPP2 (0.43) POLBKDM4EALDH1A1GAACYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9980668-B2 Photoluminescent nanostructure-based sensors MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-05-29 US claimed
EP-2739977-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS Massachusetts Institute of Technology (US) 2014-06-11 EP claimed
US-20130035567-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS NATIONAL SCIENCE FOUNDATION 2013-02-07 US claimed
WO-2013019722-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-07 WO claimed
EP-4747247-A1 NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF Apogee Pharmaceuticals, Inc. (CA) 2026-05-27 EP disclosed
EP-4212523-B1 PYRAZOLE AMIDE COMPOUNDS AS IRAK INHIBITORS RIGEL PHARMACEUTICALS INC (US) 2026-05-06 EP disclosed
US-12410137-B2 Fatty acid amide hydrolase modulators, compositions comprising the same and uses thereof APOGEE PHARMACEUTICALS, INC. (CA) 2025-09-09 US disclosed
US-20250257035-A1 1,4-Substituted Piperidine Derivatives CEPHALON LLC 2025-08-14 US disclosed
WO-2025151724-A1 PYRIDINYLOXYPYRIDINES AS MODULATORS OF ATP -BINDING CASSETTE TRANSPORTERS AND THEIR USE IN TREATING MEDICAL CONDITIONS RECTIFY PHARMACEUTICALS, INC. (US) 2025-07-17 WO disclosed
US-20250228835-A1 PYRIDINYLOXYPYRIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS RECTIFY PHARMACEUTICALS, INC. 2025-07-17 US disclosed
EP-4554680-A1 INHIBITORS OF HPK1 AND METHODS OF USE THEREOF Arcus Biosciences, Inc. (US) 2025-05-21 EP disclosed
US-20250129027-A1 FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF APOGEE PHARMACEUTICALS, INC. (CA) 2025-04-24 US disclosed
WO-2007015809-A2 HIV REVERSE TRANSCRIPTASE INHIBITORS MERCK & CO., INC. (US) 2007-02-08 WO disclosed
WO-2007015809-A2 HIV REVERSE TRANSCRIPTASE INHIBITORS MERCK & CO., INC. (US) 2007-02-08 WO disclosed
US-20070021442-A1 HIV reverse transcriptase inhibitors MERCK SHARP & DOHME CORP. 2007-01-25 US disclosed
US-20070021442-A1 HIV reverse transcriptase inhibitors MERCK SHARP & DOHME CORP. 2007-01-25 US disclosed
US-20070021442-A1 HIV reverse transcriptase inhibitors MERCK SHARP & DOHME CORP. 2007-01-25 US disclosed
WO-2006113261-A2 INHIBITORS OF 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I BRISTOL-MYERS SQUIBB COMPANY (US) 2006-10-26 WO disclosed
US-20060235028-A1 Inhibitors of 11-beta hydroxysteroid dehydrogenase type I BRISTOL-MYERS SQUIBB COMPANY 2006-10-19 US disclosed
US-20060122256-A1 Biaryloxymethylarenecarboxylic acids as glycogen synthase activators GILLESPIE PAUL 2006-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250257035-A1 1,4-Substituted Piperidine Derivatives FASN, CES1, CPT1A POLB 796/4885HCAR2 325/4885CA1 4323/4885
US-20250129027-A1 FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF FAAH, FAAH2, MGLL POLB 4023/4885HCAR2 64/4885CA1 1241/4885
US-20060122256-A1 Biaryloxymethylarenecarboxylic acids as glycogen synthase activators GYS2, GYS1, GSK3A POLB 2071/4885HCAR2 93/4885CA1 2188/4885
US-20060235028-A1 Inhibitors of 11-beta hydroxysteroid dehydrogenase type I HSD11B1, HSD3B1, HSD17B1 POLB 699/4885HCAR2 1402/4885CA1 2372/4885
US-20070021442-A1 HIV reverse transcriptase inhibitors POLRMT, RNGTT, POLR2E POLB 21/4885HCAR2 4238/4885CA1 4588/4885
US-12410137-B2 Fatty acid amide hydrolase modulators, compositions comprising the same and uses thereof FAAH, FAAH2, MGLL POLB 4023/4885HCAR2 64/4885CA1 1241/4885
US-20250228835-A1 PYRIDINYLOXYPYRIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS P2RY6, P2RY4, PNPO POLB 2735/4885HCAR2 576/4885CA1 4825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.