Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 4/20 | 0.41 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.41 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11323343 | 0.95 | CA1 (0.37) | CA1CA2CES2CES1PTGS1 | |
| SCHEMBL3162012 | 0.87 | NFE2L2 (0.48) | PTGS1HTR2AHTR2CKCNH2FBP1 | |
| SCHEMBL3162027 | 0.87 | NFE2L2 (0.48) | PTGS1HTR2AHTR2CKCNH2FBP1 | |
| SCHEMBL5354757 | 0.78 | CA12 (0.56) | CA1CA2CA7CA9MMP1 | |
| SCHEMBL4070873 | 0.77 | PGR (0.42) | CA1CA2PTGS1CA9MEN1 | |
| SCHEMBL1583683 | 0.76 | CES2 (0.36) | CA1CES2CES1CA9 | |
| SCHEMBL10689245 | 0.74 | MEN1 (0.42) | CA1CA2CA7CA9MMP1 | |
| SCHEMBL3015881 | 0.74 | CYP2A6 (0.42) | CA1CA2CES2CES1CA9 | |
| SCHEMBL6691371 | 0.74 | CA1 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL749971 | 0.74 | LMNA (0.42) | CA1CA2CES2CES1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136752-A | Alkenyl substituted tellurium organic compound, preparation method and application thereof in resisting plant pathogenic bacteria | 贵州大学 | 2025-06-13 | — | — | CN | claimed |
| CN-118930487-A | 1,3, 5-Trisubstituted pyrazole compound and preparation method thereof | 赣南师范大学 | 2024-11-12 | — | — | CN | claimed |
| CN-118834161-A | Preparation method of 3-sulfonyl-5-acetyl-1, 4 dihydropyridine compound | 西北工业大学 | 2024-10-25 | — | — | CN | claimed |
| CN-118619916-A | Sulfoxide imine N-sulfinylation compound and preparation method thereof | 上海大学 | 2024-09-10 | — | — | CN | claimed |
| CN-117926289-A | Method for electrochemically synthesizing N-sulfoamidine derivatives under mild condition | 湘潭大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117821998-A | Sulfonylation reaction method for electrochemically catalyzing organic boric acid | 南京林业大学 | 2024-04-05 | — | — | CN | claimed |
| CN-117430125-A | Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve | 常州大学 | 2024-01-23 | — | — | CN | claimed |
| CN-114230496-B | Aromatic sulfinic acid compound and preparation method thereof | 达高工业技术研究院(广州)有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-111943925-B | Synthesis method of chromanone compounds | 吉林警察学院 | 2023-04-14 | — | — | CN | claimed |
| CN-114591208-B | Synthetic method of gamma-mercapto-beta-sulfonyl methyl butyrate | 成都理工大学 | 2023-02-10 | — | — | CN | claimed |
| CN-112624898-B | Synthetic method of aryl trifluoroethylene compound | 中昊晨光化工研究院有限公司 | 2022-03-22 | — | — | CN | claimed |
| US-9650330-B2 | Process for the synthesis of aryl sulfones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-16 | — | — | US | claimed |
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | US | claimed |
| WO-2015087352-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-18 | — | — | WO | claimed |
| EP-1506170-B1 | METHOD FOR PRODUCING BICALUTAMIDE | HELM AG (DE) | 2008-02-27 | — | — | EP | claimed |
| US-7323584-B2 | Process for preparing N-(4′-cyano-3′-trifluoromethylphenyl)-3-(4″-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | HELM AG (DE) | 2008-01-29 | — | — | US | claimed |
| US-20050033082-A1 | Method for producing bicalutamide | CF PHARMA GYOGYSZERGYARTO KFT. (HU) | 2005-02-10 | — | — | US | claimed |
| EP-0687671-B1 | Method for the preparation of 4-fluorothiophenol | BAYER AG (DE) | 1997-09-10 | — | — | EP | claimed |
| US-5659088-A | Process for the preparation of 4-fluorothiophenol | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | claimed |
| US-5008369-A | Preparation of polysulfones | EASTMAN KODAK COMPANY (US) | 1991-04-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | ARSA, TPST2, STS | CA1 3612/4885CA2 1552/4885PTGS1 679/4885 |
| US-20050033082-A1 | Method for producing bicalutamide | BRDT, NPEPPS, TET3 | CA1 359/4885CA2 1238/4885PTGS1 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.