Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 5/20 | 0.60 |
| ▸ | PTGS1 known ✓ | P23219 | 2/20 | 0.60 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.60 |
| ▸ | PPARD | Q03181 | 5/20 | 0.60 |
| ▸ | PPARA | Q07869 | 5/20 | 0.60 |
| ▸ | F7 | P08709 | 5/20 | 0.60 |
| ▸ | F3 | P13726 | 5/20 | 0.60 |
| ▸ | TERT | O14746 | 3/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | FABP4 | P15090 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL8742933 | 0.92 | GPR84 (0.53) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| Oleic Acid SCHEMBL6519043 | 0.90 | FABP3 (0.63) | FAAHEPHX2FABP3 | |
| Oleic Acid SCHEMBL20162207 | 0.86 | TERT (0.64) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28352028 | 0.86 | PPARG (0.77) | PPARGPPARDPPARAF7F3 | |
| Sulfuric Acid SCHEMBL23933747 | 0.84 | PPARG (0.79) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28882414 | 0.83 | PPARG (0.72) | PPARGPPARDPPARAF7F3 | |
| Stearic Acid SCHEMBL27469346 | 0.83 | TERT (0.77) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL8881225 | 0.83 | PPARG (0.77) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28165912 | 0.83 | PPARG (0.77) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL29047777 | 0.82 | PPARG (0.74) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9144554-B2 | Topical compositions for use in the prevention and/or treatment of dermatitis | CUTRUPI CARMELO (IT) | 2015-09-29 | — | — | US | claimed |
| US-12612578-B2 | Laundry detergent compositions | HENKEL AG & CO. KGAA (DE) | 2026-04-28 | — | — | US | disclosed |
| EP-4711436-A1 | DETERGENT COMPOSITION WITH PEPTIDES AND PROTEINS | Henkel AG & Co. KGaA (DE) | 2026-03-18 | — | — | EP | disclosed |
| WO-2026044184-A1 | LIQUID DETERGENTS WITH IMPROVED MILDNESS FOR SENSITIVE SKIN | HENKEL AG & CO. KGAA (DE) | 2026-02-26 | — | — | WO | disclosed |
| US-20260055340-A1 | LIQUID DETERGENTS WITH IMPROVED MILDNESS FOR SENSITIVE SKIN | HENKEL AG & CO. KGAA (DE) | 2026-02-26 | — | — | US | disclosed |
| EP-4695371-A1 | UNIT DOSE DETERGENT COMPOSITION WITH AMINO ACID | Henkel AG & Co. KGaA (DE) | 2026-02-18 | — | — | EP | disclosed |
| EP-4695369-A1 | ENZYMATIC DETERGENT COMPOSITION WITH AMINO ACID | Henkel AG & Co. KGaA (DE) | 2026-02-18 | — | — | EP | disclosed |
| EP-4695370-A1 | NON-ENZYMATIC, HIGH PH DETERGENT COMPOSITION WITH AMINO ACID | Henkel AG & Co. KGaA (DE) | 2026-02-18 | — | — | EP | disclosed |
| US-20250326988-A1 | SELF-PRESERVED, MILD LIQUID LAUNDRY DETERGENT FORMULAS | HENKEL AG & CO. KGAA (DE) | 2025-10-23 | — | — | US | disclosed |
| EP-4636065-A1 | SELF-PRESERVED, MILD LIQUID LAUNDRY DETERGENT FORMULAS | Henkel AG & Co. KGaA (DE) | 2025-10-22 | — | — | EP | disclosed |
| US-20250136899-A1 | MILD LAUNDRY FORMULAS WITH HIGH SOLVENT RATIO AND ENZYMES FOR IMPROVED MILDNESS | HENKEL AG & CO. KGAA (DE) | 2025-05-01 | — | — | US | disclosed |
| US-20250066692-A1 | DETERGENT COMPOSITION WITH PEPTIDES AND PROTEINS | HENKEL AG & CO. KGAA (DE) | 2025-02-27 | — | — | US | disclosed |
| WO-2024215952-A1 | ENZYMATIC DETERGENT COMPOSITION WITH AMINO ACID | HENKEL AG & CO. KGAA (DE) | 2024-10-17 | — | — | WO | disclosed |
| US-20240343998-A1 | ENZYMATIC DETERGENT COMPOSITION WITH AMINO ACID | HENKEL AG & CO. KGAA (DE) | 2024-10-17 | — | — | US | disclosed |
| WO-2024215955-A1 | UNIT DOSE DETERGENT COMPOSITION WITH AMINO ACID | HENKEL AG & CO. KGAA (DE) | 2024-10-17 | — | — | WO | disclosed |
| US-20240343999-A1 | NON-ENZYMATIC, HIGH PH DETERGENT COMPOSITION WITH AMINO ACID | HENKEL AG & CO. KGAA (DE) | 2024-10-17 | — | — | US | disclosed |
| WO-2024215954-A1 | NON-ENZYMATIC, HIGH pH DETERGENT COMPOSITION WITH AMINO ACID | HENKEL AG & CO. KGAA (DE) | 2024-10-17 | — | — | WO | disclosed |
| US-20240344001-A1 | UNIT DOSE DETERGENT COMPOSITION WITH AMINO ACID | HENKEL AG & CO. KGAA (DE) | 2024-10-17 | — | — | US | disclosed |
| US-20240240113-A1 | LAUNDRY DETERGENT COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2024-07-18 | — | — | US | disclosed |
| US-9144554-B2 | Topical compositions for use in the prevention and/or treatment of dermatitis | CUTRUPI CARMELO (IT) | 2015-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612578-B2 | Laundry detergent compositions | LIPC, LPL, LIPA | PPARG 824/4885PTGS1 3903/4885ADORA3 3331/4885 |
| US-20260055340-A1 | LIQUID DETERGENTS WITH IMPROVED MILDNESS FOR SENSITIVE SKIN | DSG1, DSC1, SMURF1 | PPARG 326/4885PTGS1 2767/4885ADORA3 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.