SCHEMBL1718014

SCHEMBL1718014

CS(=O)(=O)O.c1ccc([I+]c2ccccc2)cc1

nearest known ligand 0.44

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.37
KEAP1 Q14145 1/20 0.44
TSHR P16473 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 3/20 0.42
MAPT P10636 3/20 0.42
HPGD P15428 2/20 0.42
CA2 P00918 3/20 0.39
CA1 P00915 2/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
LMNA P02545 3/20 0.38
PMP22 Q01453 3/20 0.38
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 2/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL1780831 0.90 KDM4E (0.50) TSHRSMN1; SMN2KDM4EMAPTHPGD
Sulfuric Acid SCHEMBL1062108 0.85 TSHR (0.44) TSHRSMN1; SMN2KDM4EMAPTHPGD
SCHEMBL1628635 0.85 KEAP1 (0.39) KEAP1CA2MMP2NPSR1CA12
SCHEMBL978653 0.79 TSHR (0.39) TSHRSMN1; SMN2KDM4EMAPTHPGD
Trifluoromethanesulfonic Acid SCHEMBL758916 0.79 PTPN1 (0.41) TSHRSMN1; SMN2KDM4EMAPTHPGD
Anthraquinone SCHEMBL1405501 0.79 MEN1 (0.52) TSHRSMN1; SMN2KDM4EMAPTHPGD
SCHEMBL8972780 0.79 TSHR (0.39) TSHRSMN1; SMN2KDM4EMAPTHPGD
Sulfuric Acid SCHEMBL1777697 0.79 HTR6 (0.39) TSHRSMN1; SMN2KDM4EMAPTHPGD
SCHEMBL7164635 0.78 MYC (0.43) TSHRSMN1; SMN2KDM4ECA2CA1
SCHEMBL36560 0.78 ALDH1A1 (0.40) TSHRCA2CA1LMNAPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6566036-B2 Comprising polyhydroxystyrene protected by 1-ethoxyethanol, photosensitive acid generator, solvent and polystyrene filler; dimensional and shape control of semiconductors; responsive to design rule of <0.15mu m; miniaturization NEC ELECTRONICS CORPORATION (JP) 2003-05-20 US claimed
US-20010009749-A1 Chemically amplified resist NEC CORPORATION 2001-07-26 US claimed
US-20260117080-A1 METAL OXIDE PARTICLES HAVING CORE/SHELL STRUCTURE HAVING UNIFORM PARTICLE SIZE DISTRIBUTION, AND METHOD FOR PRODUCING SAME NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
US-12606711-B2 Conductive stannic oxide particle-containing organic solvent-dispersed sol and method of production thereof NISSAN CHEMICAL CORPORATION (JP) 2026-04-21 US disclosed
US-20250256980-A1 METAL OXIDE PARTICLE HAVING CORE-SHELL STRUCTURE AND METHOD FOR PRODUCING SAME NISSAN CHEMICAL CORPORATION (JP) 2025-08-14 US disclosed
US-12359039-B2 Metal oxide particle-containing composition with reduced occurrence of volatile aldehydes NISSAN CHEMICAL CORPORATION (JP) 2025-07-15 US disclosed
WO-2025127152-A1 METAL OXIDE PARTICLES HAVING IMPROVED HYDROPHOBICITY, HIGHLY CONCENTRATED METAL OXIDE SOL, AND METHODS FOR PRODUCING SAME 日産化学株式会社 2025-06-19 WO disclosed
CN-119894824-A Hollow silica sol containing 1-valent alkali metal ion and method for producing same 日产化学株式会社 2025-04-25 CN disclosed
WO-2025084429-A1 SILICA PARTICLES FOR COATING COMPOSITION AND LAMINATED SUBSTRATE 日産化学株式会社 2025-04-24 WO disclosed
EP-4541769-A1 METAL OXIDE PARTICLE HAVING CORE-SHELL STRUCTURE AND METHOD FOR PRODUCING SAME Nissan Chemical Corporation (JP) 2025-04-23 EP disclosed
WO-2025069657-A1 METAL OXIDE PARTICLES WITH COATING AND VARNISH USING SAME 日産化学株式会社 2025-04-03 WO disclosed
US-7517619-B2 Dye-containing resist composition and color filter using same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-04-14 US disclosed
US-20080311492-A1 INKLESS REIMAGEABLE PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US disclosed
EP-2003501-A1 Inkless reimageable printing paper and method Xerox Corporation (US) 2008-12-17 EP disclosed
US-20070020559-A1 Positive-type photosensitive resin composition and cured film manufactured therefrom NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-01-25 US disclosed
US-20060172206-A1 Dye-containing resist composition and color filter using same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-03 US disclosed
US-20050227169-A1 Dye-containing resist composition and color filter using same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-10-13 US disclosed
US-20050095530-A1 Dye-containing resist composition and color filter using same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-05-05 US disclosed
EP-1508835-A2 Dye-containing resist composition and color filter using same NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 2005-02-23 EP disclosed
US-6509125-B1 Colored layers containing a dye-bonded polymer TOPPAN PRINTING CO., LTD. (JP) 2003-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117080-A1 METAL OXIDE PARTICLES HAVING CORE/SHELL STRUCTURE HAVING UNIFORM PARTICLE SIZE DISTRIBUTION, AND METHOD FOR PRODUCING SAME CD63, SLC39A3, ZRANB2 SLC6A2 1916/4885KEAP1 4149/4885TSHR 76/4885
US-12606711-B2 Conductive stannic oxide particle-containing organic solvent-dispersed sol and method of production thereof SCO2, SOD1, SPOP SLC6A2 1083/4885KEAP1 4768/4885TSHR 1394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.