Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.46 |
| ▸ | FABP3 | P05413 | 2/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986182 | 0.98 | CA1 (0.56) | CA1ALDH1A1TSHRFFAR3HDAC3 | |
| SCHEMBL25232579 | 0.98 | CA1 (0.56) | CA1ALDH1A1TSHRFFAR3HDAC3 | |
| SCHEMBL25246688 | 0.98 | CA1 (0.56) | CA1ALDH1A1TSHRFFAR3HDAC3 | |
| SCHEMBL25240427 | 0.98 | CA1 (0.56) | CA1ALDH1A1TSHRFFAR3HDAC3 | |
| SCHEMBL25211845 | 0.98 | CA1 (0.56) | CA1ALDH1A1TSHRFFAR3HDAC3 | |
| SCHEMBL25243757 | 0.98 | CA1 (0.56) | CA1ALDH1A1TSHRFFAR3HDAC3 | |
| SCHEMBL25253609 | 0.98 | CA1 (0.56) | CA1ALDH1A1TSHRFFAR3HDAC3 | |
| SCHEMBL25245607 | 0.98 | CA1 (0.56) | CA1ALDH1A1TSHRFFAR3HDAC3 | |
| SCHEMBL25246807 | 0.98 | CA1 (0.56) | CA1ALDH1A1TSHRFFAR3HDAC3 | |
| SCHEMBL25255737 | 0.98 | CA1 (0.56) | CA1ALDH1A1TSHRFFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508169-B1 | POLYMERSOME AND PROCESS FOR PRODUCING SAME | SHISEIDO CO LTD (JP) | 2018-09-05 | — | — | EP | disclosed |
| US-8603533-B2 | Polymersomes and production method thereof | SHISEIDO COMPANY, LTD. (JP) | 2013-12-10 | — | — | US | disclosed |
| EP-2508169-A1 | POLYMERSOME AND PROCESS FOR PRODUCING SAME | Shiseido Company, Ltd. (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-20120231055-A1 | Polymersomes And Production Method Thereof | SHISEIDO COMPANY, LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| EP-2092931-B1 | Oil-in-water emulsified milky skin cosmetic preparation | SHISEIDO CO LTD (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-8182828-B2 | Oil-in-water emulsified milky skin cosmetic preparation | SHISEIDO COMPANY LTD. (JP) | 2012-05-22 | — | — | US | disclosed |
| US-20120093747-A1 | SUNSCREEN COSMETIC COMPOSITION CONTAINING ULTRAVIOLET ABSORBER | ADEKA CORPORATION (JP) | 2012-04-19 | — | — | US | disclosed |
| US-8153142-B2 | Skin treatment composition | SHISEIDO CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20120058065-A1 | Oil-Based Skin Treatment Composition | SHISEIDO COMPANY, LTD. (JP) | 2012-03-08 | — | — | US | disclosed |
| EP-2420221-A1 | POWDERED SOLID COSMETIC AND MANUFACTURING METHOD THEREFOR | Shiseido Company, Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20120039971-A1 | Solid Powder Cosmetic And Method For Producing The Same | SHISEIDO COMPANY, LTD. (JP) | 2012-02-16 | — | — | US | disclosed |
| WO-2011137938-A1 | COSMETIC COMPOSITION COMPRISING BORON NITRIDE COMPLEX POWDER | CHANEL PARFUMS BEAUTE (FR) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011069915-A1 | COMPOSITION FOR EXTERNAL USE AND METHOD FOR PRODUCING THE SAME | CHANEL PARFUMS BEAUTE (FR) | 2011-06-16 | — | — | WO | disclosed |
| US-20110098231-A1 | Skin Cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2011-04-28 | — | — | US | disclosed |
| EP-2092931-A1 | Oil-in-water emulsified milky skin cosmetic preparation | Shiseido Co., Ltd. (JP) | 2009-08-26 | — | — | EP | disclosed |
| US-20090202600-A1 | Oil-In-Water Emulsified Milky Skin Cosmetic Preparation | SHISEIDO COMPANY LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20070196349-A1 | Whitening composition containing reduced coenzyme Q | KANEKA CORPORATION (JP) | 2007-08-23 | — | — | US | disclosed |
| EP-1790238-A1 | WHITENING COMPOSITION CONTAINING REDUCED COENZYME Q | Kaneka Corporation (JP) | 2007-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120039971-A1 | Solid Powder Cosmetic And Method For Producing The Same | SETDB1, FABP4, CUTA | CA1 967/4885ALDH1A1 2046/4885TSHR 535/4885 |
| US-20090202600-A1 | Oil-In-Water Emulsified Milky Skin Cosmetic Preparation | CUTA, ACMSD, MC1R | CA1 3738/4885ALDH1A1 2642/4885TSHR 1743/4885 |
| US-20120093747-A1 | SUNSCREEN COSMETIC COMPOSITION CONTAINING ULTRAVIOLET ABSORBER | CYP8B1, TYR, ERCC5 | CA1 4170/4885ALDH1A1 188/4885TSHR 1618/4885 |
| US-20070196349-A1 | Whitening composition containing reduced coenzyme Q | NDUFA7, NDUFA11, NDUFA12 | CA1 4800/4885ALDH1A1 244/4885TSHR 4410/4885 |
| US-20110098231-A1 | Skin Cosmetic | CUTA, DEGS1, ALAD | CA1 3772/4885ALDH1A1 1951/4885TSHR 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.