SCHEMBL175622

SCHEMBL175622

C=CCOCC=C.CCOc1ccc(CO)cc1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 2/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
TSHR P16473 2/20 0.52
TP53 P04637 1/20 0.52
CYP2D6 P10635 2/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 4/20 0.49
CALM1 P0DP23 3/20 0.49
GAA P10253 2/20 0.49
MAPT P10636 2/20 0.49
HTT P42858 2/20 0.49
PPARA Q07869 2/20 0.49
PPARG P37231 1/20 0.49
PPARD Q03181 1/20 0.49
POLB P06746 2/20 0.47
PTGS1 P23219 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168322 0.87 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2LMNANPC1RAB9A
SCHEMBL30714383 0.87 CALM1 (0.61) SMN1; SMN2LMNANPC1RAB9ATSHR
SCHEMBL579760 0.87 CALM1 (0.61) SMN1; SMN2LMNANPC1RAB9ATSHR
Acetone SCHEMBL4796453 0.82 KDM4E (0.59) ALDH1A1SMN1; SMN2LMNANPC1RAB9A
Vanillyl Alcohol SCHEMBL168321 0.81 ALDH1A1 (0.65) ALDH1A1LMNATSHRCYP2D6CALM1
SCHEMBL4877099 0.81 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2LMNANPC1RAB9A
SCHEMBL3972900 0.80 L3MBTL1 (0.54) ALDH1A1NPC1RAB9ATSHRKMT2A
Ethyleugenol SCHEMBL357018 0.79 ALDH1A1 (0.77) ALDH1A1SMN1; SMN2LMNANPC1RAB9A
SCHEMBL697888 0.78 HTT (0.61) ALDH1A1SMN1; SMN2LMNANPC1RAB9A
SCHEMBL22215808 0.77 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2LMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9974740-B2 Sensation masking composition TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2018-05-22 US claimed
EP-2810564-B1 Sensation masking composition TAKASAGO INT CORP (USA) (US) 2017-06-14 EP claimed
US-20150327583-A1 SENSATION MASKING COMPOSITION TAKASAGO INTERNATIONAL CORP. (USA) (US) 2015-11-19 US claimed
US-8920864-B2 Sensation masking composition TAKASAGO INTERNATIONAL CORPORATION (US) 2014-12-30 US claimed
EP-2810564-A1 Sensation masking composition Takasago International Corporation (USA) (US) 2014-12-10 EP claimed
EP-1912516-B1 SENSATION MASKING COMPOSITION TAKASAGO INTERNAT CORP USA (US) 2014-06-25 EP claimed
US-20100093869-A1 SENSATION MASKING COMPOSITION TAKASAGO INTERNATIONAL CORP. (USA) 2010-04-15 US claimed
US-20080253973-A1 SENSATION MODIFYING TOPICAL COMPOSITION FOAM FOAMIX LTD. (IL) 2008-10-16 US claimed
EP-1912516-A2 SENSATION MASKING COMPOSITION Takasago International Corporation (USA) (US) 2008-04-23 EP claimed
WO-2007022056-A2 SENSATION MASKING COMPOSITION TAKASAGO INTERNATIONAL CORP. (USA) (US) 2007-02-22 WO claimed
US-20070036733-A1 Sensation masking composition TAKASAGO INTERNATIONAL CORP. (USA) (US) 2007-02-15 US claimed
EP-4392010-A1 ORAL CARE COMPOSITIONS FOR GUM HEALTH The Procter & Gamble Company (US) 2024-07-03 EP disclosed
EP-4391992-A1 ORAL CARE COMPOSITIONS FOR GUM HEALTH The Procter & Gamble Company (US) 2024-07-03 EP disclosed
US-20240122838-A1 LEAVE-ON ORAL CARE COMPOSITIONS PROCTER & GAMBLE (US) 2024-04-18 US disclosed
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents COLABS INT'L CORP. (US) 2024-03-28 US disclosed
US-6673844-B2 REDUCING SKIN SENSITIVITY TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-01-06 US disclosed
US-20020142015-A1 Warming composition TAKASAGO INTERNATIONAL CORPORATION 2002-10-03 US disclosed
US-20020119231-A1 Warming composition for food and drink or for oral care preparation TAKASAGO INTERNATIONAL CORPORATION 2002-08-29 US disclosed
EP-1215257-A2 Warming composition Takasago International Corporation (JP) 2002-06-19 EP disclosed
EP-1215258-A2 Waming composition for food and drink or for oral care preparation Takasago International Corporation (JP) 2002-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070036733-A1 Sensation masking composition TRPA1, TRPV1, TRPM5 ALDH1A1 765/4885SMN1; SMN2 2603/4885LMNA 4500/4885
US-20100093869-A1 SENSATION MASKING COMPOSITION TRPA1, TRPV1, TRPM5 ALDH1A1 765/4885SMN1; SMN2 2603/4885LMNA 4500/4885
US-20020142015-A1 Warming composition CUTA, TRPA1, POLR1C ALDH1A1 1699/4885SMN1; SMN2 1998/4885LMNA 2473/4885
US-20080253973-A1 SENSATION MODIFYING TOPICAL COMPOSITION FOAM TRPA1, GPR35, TRPV1 ALDH1A1 2137/4885SMN1; SMN2 1331/4885LMNA 2508/4885
US-20150327583-A1 SENSATION MASKING COMPOSITION TRPA1, TRPV1, TRPM5 ALDH1A1 765/4885SMN1; SMN2 2603/4885LMNA 4500/4885
US-20020119231-A1 Warming composition for food and drink or for oral care preparation TAS2R40, TAS2R39, TAS2R20 ALDH1A1 2888/4885SMN1; SMN2 920/4885LMNA 996/4885
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents MSN, LIPE, CUTA ALDH1A1 1189/4885SMN1; SMN2 937/4885LMNA 3449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.