SCHEMBL18022262

SCHEMBL18022262

CC(C)(C)c1cccc(-c2ccc3c4ccccc4n(-c4ccccc4)c3c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
RXRA P19793 3/20 0.44
RXRB P28702 3/20 0.44
KIF11 P52732 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
KMT2A Q03164 2/20 0.40
PPARG P37231 3/20 0.39
PPARA Q07869 1/20 0.39
SERPINE1 P05121 1/20 0.38
OPRD1 P41143 3/20 0.37
IL1R1 P14778 1/20 0.37
NOTUM Q6P988 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
OPRM1 P35372 1/20 0.36
OPRK1 P41145 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25991421 0.93 KDM4E (0.45) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL18022256 0.93 L3MBTL1 (0.51) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL20052628 0.92 KDM4E (0.47) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL24793867 0.90 KDM4E (0.49) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL26050683 0.90 L3MBTL1 (0.49) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL26050734 0.90 L3MBTL1 (0.49) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL12000705 0.90 KIF11 (0.49) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL18627212 0.89 KDM4E (0.44) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL19735293 0.89 RXRA (0.48) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL23184829 0.89 KDM4E (0.50) L3MBTL1KDM4EATMRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691952-B2 Nitrogen-containing compound, and electronic element and electronic device using same SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-07-04 US disclosed
US-20230183191-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-11 US disclosed
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-11 US disclosed
US-11211568-B2 Compound for organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2021-12-28 US disclosed
US-10807972-B2 Indenotriphenylene-based amine derivative and organic electroluminescence device using the same NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2020-10-20 US disclosed
US-20200115369-A1 INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-04-16 US disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-9929351-B2 Indenotriphenylene-based amine derivative for organic electroluminescent device NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2018-03-27 US disclosed
US-9929351-B2 Indenotriphenylene-based amine derivative for organic electroluminescent device NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2018-03-27 US disclosed
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-12-21 US disclosed
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-12-21 US disclosed
US-9812649-B2 Indenotriphenylene-based amine derivative for organic electroluminescent device NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2017-11-07 US disclosed
US-9812649-B2 Indenotriphenylene-based amine derivative for organic electroluminescent device NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2017-11-07 US disclosed
US-20160240784-A1 INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE FOR ORGANIC ELECTROLUMINESCENT DEVICE NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2016-08-18 US disclosed
US-20160240783-A1 INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE FOR ORGANIC ELECTROLUMINESCENT DEVICE NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2016-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160240784-A1 INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE FOR ORGANIC ELECTROLUMINESCENT DEVICE AHR, MLLT1, AR L3MBTL1 80/4885KDM4E 389/4885ATM 1177/4885
US-10807972-B2 Indenotriphenylene-based amine derivative and organic electroluminescence device using the same ICMT, INMT, PNMT L3MBTL1 538/4885KDM4E 749/4885ATM 1698/4885
US-20160240783-A1 INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE FOR ORGANIC ELECTROLUMINESCENT DEVICE PNMT, PNN, INMT L3MBTL1 52/4885KDM4E 977/4885ATM 1599/4885
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE OCIAD2, AOC2, OCIAD1 L3MBTL1 4055/4885KDM4E 1366/4885ATM 2496/4885
US-11211568-B2 Compound for organic electroluminescence device using the same OR10J3, PIEZO1, ICMT L3MBTL1 675/4885KDM4E 1352/4885ATM 3347/4885
US-20230183191-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE CNOT1, NXF1, NR2E1 L3MBTL1 2672/4885KDM4E 2423/4885ATM 625/4885
US-20200115369-A1 INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME ICMT, INMT, PNMT L3MBTL1 538/4885KDM4E 749/4885ATM 1698/4885
US-11691952-B2 Nitrogen-containing compound, and electronic element and electronic device using same NOD1, NFE2L2, NOTCH1 L3MBTL1 3904/4885KDM4E 837/4885ATM 4541/4885
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, NR2E3, LEF1 L3MBTL1 3362/4885KDM4E 3359/4885ATM 1650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.