Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.40 |
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GRK2 | P25098 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.48 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807909 | 1.00 | PTPN1 (0.57) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29377239 | 1.00 | PTPN1 (0.57) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29534088 | 0.88 | ENPP2 (0.50) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29350172 | 0.87 | ENPP2 (0.56) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL2121243 | 0.87 | ENPP2 (0.56) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL2121238 | 0.87 | ENPP2 (0.56) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL185815 | 0.87 | ENPP2 (0.56) | MEN1KMT2AENPP2FUT8HTT | |
| SCHEMBL1139743 | 0.87 | ENPP2 (0.56) | MEN1KMT2AENPP2FUT8HTT | |
| SCHEMBL110153 | 0.87 | ENPP2 (0.56) | MEN1KMT2AENPP2FUT8HTT | |
| SCHEMBL28343203 | 0.86 | USP2 (0.52) | PTPN1USP2ATML3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2930126-B1 | Fashionable aerosol dye | HENKEL AG & CO KGAA (DE) | 2019-10-09 | — | — | EP | claimed |
| US-10259946-B1 | Sealing agents, methods of making and uses thereof | James Hardie Technology Limited (IE) | 2019-04-16 | — | — | US | disclosed |
| US-9173829-B2 | Compositions for dyeing keratin fibers | HENKEL AG & CO. KGAA (DE) | 2015-11-03 | — | — | US | disclosed |
| US-9161898-B2 | Compositions for colouring keratin fibres | HENKEL AG & CO. KGAA (DE) | 2015-10-20 | — | — | US | disclosed |
| US-20140298592-A1 | COMPOSITIONS FOR DYEING KERATIN FIBERS | HENKEL AG & CO. KGAA (DE) | 2014-10-09 | — | — | US | disclosed |
| US-20140290690-A1 | COMPOSITIONS FOR COLOURING KERATIN FIBRES | HENKEL AG & CO. KGAA (DE) | 2014-10-02 | — | — | US | disclosed |
| US-8632612-B2 | Compositions for dyeing keratin fibers | SEGETIS, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| EP-2613760-A2 | COMPOSITIONS FOR DYEING KERATIN FIBERS | Segetis, Inc. (US) | 2013-07-17 | — | — | EP | disclosed |
| US-20130156716-A1 | COMPOSITIONS FOR DYEING KERATIN FIBERS | SEGETIS, INC. (US) | 2013-06-20 | — | — | US | disclosed |
| EP-2103299-B1 | Oxidizing hair colourant compositions | PROCTER & GAMBLE (US) | 2013-02-27 | — | — | EP | disclosed |
| US-6461390-B1 | Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| US-6361571-B1 | USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |
| US-6231622-B1 | MIXTURES; BLUE COLOR | WELLA AKTIENGESELLSCHAFT (DE) | 2001-05-15 | — | — | US | disclosed |
| US-6171347-B1 | REMOVAL OF HAIR COLOR TO BE WORN FOR ONLY A SHORT PERIOD OF TIME UNDER MILD, GENTLE CONDITIONS BY USING A COMBINATION OF A SUITABLE REDUCTONE, SUCH AS ASCORBIC ACID, AND/OR A THIOL AND/OR A SULFITE | WELLA AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-6146429-A | DEVELOPER, COUPLER, BEESWAX AND PROTEIN HYDROLYZATES OR AMINO ACIDS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-11-14 | — | — | US | disclosed |
| US-5865855-A | COUPLING TWO PYRAZOLE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 1999-02-02 | — | — | US | disclosed |
| US-4784959-A | Method of detecting hydrocarbon fuel leaks | LOCKHEED CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| US-4756854-A | Method and apparatus for detecting hydrocarbon fuel leaks | LOCKHEED CORPORATION (US) | 1988-07-12 | — | — | US | disclosed |
| US-4745797-A | Method and apparatus for detecting hydrocarbon fuel leaks | LOCKHEED CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |
| US-4615828-A | Method and apparatus for detecting hydrocarbon fuel leaks | LOCKHEED CORPORATION (US) | 1986-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140290690-A1 | COMPOSITIONS FOR COLOURING KERATIN FIBRES | KRT18, DSG1, PKN1 | CA2 3072/4885THRB 4544/4885PTPN1 3042/4885 |
| US-20140298592-A1 | COMPOSITIONS FOR DYEING KERATIN FIBERS | KRT18, PKN3, IK | CA2 2808/4885THRB 3252/4885PTPN1 3535/4885 |
| US-20130156716-A1 | COMPOSITIONS FOR DYEING KERATIN FIBERS | KRT18, KRTCAP2, JUP | CA2 2513/4885THRB 4745/4885PTPN1 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.