Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.71 |
| ▸ | APP | P05067 | 1/20 | 0.71 |
| ▸ | GLB1 | P16278 | 1/20 | 0.71 |
| ▸ | CHAT | P28329 | 1/20 | 0.71 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.71 |
| ▸ | CTRC | Q99895 | 1/20 | 0.71 |
| ▸ | ALB | P02768 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362889 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| SCHEMBL2868747 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| SCHEMBL23787656 | 0.87 | ALDH1A1 (0.77) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| SCHEMBL11922531 | 0.86 | SENP2 (0.79) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| SCHEMBL19154084 | 0.86 | SENP2 (0.79) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| SCHEMBL29382082 | 0.85 | THRB (0.74) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| Congo Red Free Acid SCHEMBL29395841 | 0.83 | APP (1.00) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| Congo Red Free Acid SCHEMBL29366109 | 0.83 | APP (1.00) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| Congo Red Free Acid SCHEMBL25635 | 0.83 | APP (1.00) | ALDH1A1CYP3A4THRBHPGDALOX15 | |
| Congo Red Free Acid SCHEMBL202229 | 0.83 | APP (1.00) | ALDH1A1CYP3A4THRBHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11794149-B2 | High flux, chlorine resistant coating for sulfate removal membranes | TELEDYNE SCIENTIFIC & IMAGING, LLC (US) | 2023-10-24 | — | — | US | claimed |
| CN-108136367-A | Gas filter for alkaline contaminants | 塞里奥尼克斯股份有限公司 | 2018-06-08 | — | — | CN | claimed |
| EP-3328538-A1 | GAS FILTERS FOR BASIC CONTAMINANTS | Serionix, Inc. (US) | 2018-06-06 | — | — | EP | claimed |
| CN-106573084-A | Wetness indicator with permanent colorant | 宝洁公司 | 2017-04-19 | — | — | CN | claimed |
| WO-2017040283-A1 | GAS FILTERS FOR BASIC CONTAMINANTS | SERIONIX, INC. (US) | 2017-03-09 | — | — | WO | claimed |
| US-7960176-B2 | Method and device for determining if a product is in condition for use or consumption | CRYOLOG SA (FR) | 2011-06-14 | — | — | US | claimed |
| WO-2009134794-A1 | MATERIALS AND METHODS FOR CREATING CUSTOMIZED COMPOSITIONS HAVING A TEMPORARY VISUAL INDICATOR | MELKER RICHARD J (US) | 2009-11-05 | — | — | WO | claimed |
| US-20070275467-A1 | Method and Device for Determining if a Product is in Condition for Use or Consumption | CRYOLOG S.A. (FR) | 2007-11-29 | — | — | US | claimed |
| CN-1894420-A | Method and device for determining if a product is in condition for use or consumption | CRYOLOG S A (FR) | 2007-01-10 | — | — | CN | claimed |
| US-6727278-B1 | PYRIMETHAMIN, CROMOLYN SODIUM, ERYTHYROMYCIN, PURPUROGALLIN, TARTRAZINE, SULFANILAMIDE, BENZOPURPURINE, PHTHALOCYANINE, 5-METHYL-2-THIOURIDINE AND 1,2-BENZYLSOXAZOLE CROSSES BLOOD-BRAIN BARRIER; ALZHEIMER*S DISEASE | DMS PHARMACEUTICAL INC. (CA) | 2004-04-27 | — | — | US | claimed |
| US-5567720-A | ALZHEIMER'S DISEASE | DMS PHARMACEUTICAL INC. (CA) | 1996-10-22 | — | — | US | claimed |
| EP-0460078-A1 | PHARMACEUTICALLY ACTIVE AGENTS THAT IMPEDE AMYLOID FORMATION IN VIVO | AVERBACK, Paul (CA) | 1991-12-11 | — | — | EP | claimed |
| WO-1990009789-A2 | PHARMACEUTICALLY ACTIVE AGENTS THAT IMPEDE AMYLOID FORMATION IN VIVO | AVERBACK PAUL (CA) | 1990-09-07 | — | — | WO | claimed |
| US-20260124324-A1 | PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS | TUFTS COLLEGE (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4734896-A2 | BIOPOLYMER-BASED TYMPANOSTOMY TUBES WITH PROGRAMMABLE, TUNABLE, AND ON-DEMAND DEGRADATION | Trustees Of Tufts College (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4735018-A2 | CENTRIFUGALLY-MOLDED ARTICLES AND METHODS | Trustees Of Tufts College (US) | 2026-05-06 | — | — | EP | disclosed |
| US-4835251-A | Method of chain combination | GENETECH, INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0251615-A2 | Method of chain combination | GENENTECH, INC. (US) | 1988-01-07 | — | — | EP | disclosed |
| US-4678436-A | Color-changeable cement composition for dental use | G-C DENTAL INDUSTRIAL CORP. (JP) | 1987-07-07 | — | — | US | disclosed |
| US-4584260-A | 4,41-BIS(DIALKYLAMINO)BENZOPHENONE A BENZOPHENONE, 1,3,4-OXADIAZOLE COMPOUND, AROMATIC HALOGENATED SULFONE, QUINAZOLINE AND TRIAZINE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124324-A1 | PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS | PTMS, ITK, MATK | THRB 2085/4885ALDH1A1 2540/4885CYP3A4 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.