SCHEMBL221916

SCHEMBL221916

CCCCCC1(CCCCC)NC(=O)NC1=O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 7/20 0.45
MMP9 P14780 7/20 0.45
MMP3 P08254 2/20 0.45
MMP8 P22894 5/20 0.44
MMP13 P45452 5/20 0.44
TDP1 Q9NUW8 1/20 0.39
CYP19A1 P11511 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11484713 0.98 MMP2 (0.47) MMP2MMP9MMP3MMP8MMP13
SCHEMBL11534423 0.98 MMP2 (0.47) MMP2MMP9MMP3MMP8MMP13
SCHEMBL10407006 0.98 MMP2 (0.47) MMP2MMP9MMP3MMP8MMP13
SCHEMBL6331007 0.94 TDP1 (0.40) MMP2MMP9MMP3MMP8MMP13
SCHEMBL11167483 0.92 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
SCHEMBL11534742 0.90 MMP2 (0.45) MMP2MMP9MMP3MMP8MMP13
SCHEMBL6695687 0.90 PDE7A (0.41) MMP2MMP9MMP3MMP8MMP13
SCHEMBL6692266 0.86 LMNA (0.40) MMP2MMP9MMP3MMP8MMP13
SCHEMBL2138557 0.85 PDE7A (0.46) MMP2MMP9MMP3TDP1CYP19A1
SCHEMBL28264380 0.83 MMP2 (0.43) MMP2MMP9MMP3MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 350 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197701-A1 ANDROGEN RECEPTOR INHIBITION TO TREAT SEPSIS AND SHOCK APPLIED BIOLOGY, INC. 2024-06-20 US claimed
US-20220186227-A1 Therapeutic Targets for Oncogenic KRAS-Dependent Cancers UNIVERSITY OF MASSACHUSETTS 2022-06-16 US claimed
EP-3946629-A1 THERAPEUTIC TARGETS FOR ONCOGENIC KRAS-DEPENDENT CANCERS University Of Massachusetts (US) 2022-02-09 EP claimed
WO-2020198488-A1 THERAPEUTIC TARGETS FOR ONCOGENIC KRAS-DEPENDENT CANCERS UNIVERSITY OF MASSACHUSETTS (US) 2020-10-01 WO claimed
CN-108658869-A Compound with anti-tumor activity and preparation method thereof and the purposes in pharmacy 复旦大学 2018-10-16 CN claimed
EP-3329775-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS Medivation Prostate Therapeutics LLC (US) 2018-06-06 EP claimed
US-9174943-B2 Processes for the synthesis of diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-11-03 US claimed
CN-103108549-B Method for synthesizing diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-09-09 CN claimed
WO-2015042170-A1 COMPOSITIONS AND USES OF COMBINATIONS OF DIM-RELATED INDOLES AND SELECTED ANTI-ANDROGEN COMPOUNDS WAYNE STATE UNIVERSITY (US) 2015-03-26 WO claimed
CN-104341396-A Diaryl hydantoin derivative, as well as preparation method, medicine composition and application thereof SHANGHAI PHARMACEUTICALS HOLDING CO LTD 2015-02-11 CN claimed
EP-2646553-A1 COMPOSITIONS AND METHODS FOR TREATING ANDROGEN RECEPTOR DEPENDENT DISORDERS INCLUDING CANCERS Santaris Pharma A/S (DK) 2013-10-09 EP claimed
US-20130190507-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS LLC 2013-07-25 US claimed
CN-103108549-A Method for synthesizing diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS INC 2013-05-15 CN claimed
EP-2538785-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS Medivation Prostate Therapeutics, Inc. (US) 2013-01-02 EP claimed
WO-2012065051-A1 COMPOSITIONS AND METHODS FOR TREATING ANDROGEN RECEPTOR DEPENDENT DISORDERS INCLUDING CANCERS ENZON PHARMACEUTICALS, INC. (US) 2012-05-18 WO claimed
WO-2011106570-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2011-09-01 WO claimed
EP-0232311-B1 TOPICAL COMPOSITION AND METHOD FOR STIMULATING HAIR GROWTH PROCTOR, Peter H. (US) 1993-05-12 EP claimed
EP-0192660-B1 ABSORPTION ENHANCING AGENTS SURVIVAL TECHNOLOGY, INC. (US) 1992-11-19 EP claimed
WO-1988005653-A1 TOPICAL COMPOSITION FOR STIMULATING HAIR GROWTH WITH STABLE FREE RADICALS PROCTOR PETER H (US) 1988-08-11 WO claimed
US-20240197701-A1 ANDROGEN RECEPTOR INHIBITION TO TREAT SEPSIS AND SHOCK APPLIED BIOLOGY, INC. 2024-06-20 US disclosed
US-20240197701-A1 ANDROGEN RECEPTOR INHIBITION TO TREAT SEPSIS AND SHOCK APPLIED BIOLOGY, INC. 2024-06-20 US disclosed
US-11992531-B2 C3-carbon linked glutarimide degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2024-05-28 US disclosed
US-20240132452-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-25 US disclosed
US-20240132452-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-25 US disclosed
WO-2023239750-A1 BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS C4 THERAPEUTICS, INC. (US) 2023-12-14 WO disclosed
US-20230372496-A1 TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS C4 THERAPEUTICS, INC. (US) 2023-11-23 US disclosed
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2023-11-09 US disclosed
CN-116723839-A Tricyclic heterobifunctional compounds for degrading target proteins C4医药公司 2023-09-08 CN disclosed
US-20230279023-A1 N/O-Linked Degrons and Degronimers for Protein Degradation C4 THERAPEUTICS, INC. (US) 2023-09-07 US disclosed
EP-4228625-A1 TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS C4 Therapeutics, Inc. (US) 2023-08-23 EP disclosed
EP-3717457-B1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE AARTI INDUSTRIES LTD (IN) 2023-06-21 EP disclosed
JP-2023075313-A diarylhydantoin compounds ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 2023-05-30 JP disclosed
JP-2023075313-A diarylhydantoin compounds ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 2023-05-30 JP disclosed
CN-116003328-A Diaryl hydantoin compounds 加利福尼亚大学董事会 2023-04-25 CN disclosed
US-20230109968-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-04-13 US disclosed
US-20230109968-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-04-13 US disclosed
US-20230095223-A1 SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2023-03-30 US disclosed
EP-4155403-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE Ionis Pharmaceuticals, Inc. (US) 2023-03-29 EP disclosed
US-20230014124-A1 HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2023-01-19 US disclosed
CN-110003114-B Diarylhydantoin compounds 加利福尼亚大学董事会 2023-01-17 CN disclosed
CN-110003114-B Diarylhydantoin compounds 加利福尼亚大学董事会 2023-01-17 CN disclosed
CN-110003114-B Diarylhydantoin compounds 加利福尼亚大学董事会 2023-01-17 CN disclosed
US-11524949-B2 Degraders and Degrons for targeted protein degradation C4 THERAPEUTICS, INC. (US) 2022-12-13 US disclosed
US-20220186227-A1 Therapeutic Targets for Oncogenic KRAS-Dependent Cancers UNIVERSITY OF MASSACHUSETTS 2022-06-16 US disclosed
WO-2022081928-A1 TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS C4 THERAPEUTICS, INC. (US) 2022-04-21 WO disclosed
US-11292782-B2 Diarylhydantoin compounds and methods of use thereof NUVATION BIO INC. (US) 2022-04-05 US disclosed
US-11292782-B2 Diarylhydantoin compounds and methods of use thereof NUVATION BIO INC. (US) 2022-04-05 US disclosed
CN-108300718-B Modulation of androgen receptor expression 苏州瑞博生物技术股份有限公司 2022-02-22 CN disclosed
CN-114058617-A Conjugated antisense compounds and uses thereof IONIS制药公司 2022-02-18 CN disclosed
EP-3946629-A1 THERAPEUTIC TARGETS FOR ONCOGENIC KRAS-DEPENDENT CANCERS University Of Massachusetts (US) 2022-02-09 EP disclosed
CN-108064162-B Conjugated antisense compounds and uses thereof IONIS制药公司 2021-12-03 CN disclosed
US-11185592-B2 Spirocyclic degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2021-11-30 US disclosed
EP-3897631-A1 TARGETED PROTEIN DEGRADATION C4 Therapeutics, Inc. (US) 2021-10-27 EP disclosed
EP-3886853-A1 DIARYLHYDANTOIN COMPOUNDS AND METHODS OF USE THEREOF Nuvation Bio Inc. (US) 2021-10-06 EP disclosed
CN-105873917-B Non-steroidal antiandrogens and selective androgen receptor modulators containing a pyridyl moiety 恩多研究公司 2021-08-10 CN disclosed
US-20210238145-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-05 US disclosed
US-20210238145-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-05 US disclosed
EP-3329775-B1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS LLC (US) 2021-04-21 EP disclosed
US-20210106688-A1 SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2021-04-15 US disclosed
EP-3791724-A1 TREATMENT OF BREAST CANCER Medivation Prostate Therapeutics LLC (US) 2021-03-17 EP disclosed
US-20210069154-A1 Treatment of Breast Cancer MEDIVATION PROSTATE THERAPEUTICS LLC 2021-03-11 US disclosed
US-RE48461-E1 Modulation of androgen receptor expression lonis Pharmaceuticals, Inc. (US) 2021-03-09 US disclosed
US-20210054017-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE IONIS PHARMACEUTICALS INC (US) 2021-02-25 US disclosed
US-10905768-B1 Heterocyclic degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2021-02-02 US disclosed
US-10849982-B2 C3-carbon linked glutarimide degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2020-12-01 US disclosed
US-10844379-B2 Conjugated antisense compounds and their use IONIS PHARMACEUTICALS, INC. (US) 2020-11-24 US disclosed
EP-3717457-A1 PROCESS FOR PREPARATION OF ENZALUTAMIDE USING NOVEL INTERMEDIATE Aarti Industries Limited (IN) 2020-10-07 EP disclosed
WO-2020198488-A1 THERAPEUTIC TARGETS FOR ONCOGENIC KRAS-DEPENDENT CANCERS UNIVERSITY OF MASSACHUSETTS (US) 2020-10-01 WO disclosed
EP-3710002-A2 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION C4 Therapeutics, Inc. (US) 2020-09-23 EP disclosed
CN-111386257-A Process for preparing enzalutamide using novel intermediates 阿尔第实业有限公司 2020-07-07 CN disclosed
WO-2020132561-A1 TARGETED PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2020-06-25 WO disclosed
US-20200199098-A1 DIARYLHYDANTOIN COMPOUNDS AND METHODS OF USE THEREOF SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) 2020-06-25 US disclosed
WO-2020113088-A1 DIARYLHYDANTOIN COMPOUNDS AND METHODS OF USE THEREOF NUVATION BIO INC. (US) 2020-06-04 WO disclosed
US-10660968-B2 Spirocyclic degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2020-05-26 US disclosed
US-20200157548-A1 COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS IONIS PHARMACEUTICALS, INC. (US) 2020-05-21 US disclosed
US-10646575-B2 Heterocyclic degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2020-05-12 US disclosed
US-20200140456-A1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2020-05-07 US disclosed
EP-3641762-A1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION C4 Therapeutics, Inc. (US) 2020-04-29 EP disclosed
US-10626091-B2 Process for the preparation of enzalutamide LAURUS LABS LIMITED (IN) 2020-04-21 US disclosed
US-20200079741-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-03-12 US disclosed
US-20200079741-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-03-12 US disclosed
US-10570169-B2 Conjugated antisense compounds and their use IONIS PHARMACEUTICALS, INC. (US) 2020-02-25 US disclosed
EP-3610731-A1 TREATMENT OF BREAST CANCER Medivation Prostate Therapeutics LLC (US) 2020-02-19 EP disclosed
EP-3546579-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE Ionis Pharmaceuticals, Inc. (US) 2019-10-02 EP disclosed
US-20190262315-A1 Treatment of Breast Cancer MEDIVATION PROSTATE THERAPEUTICS, INC. 2019-08-29 US disclosed
CN-110003114-A Diarylhydantoin compounds 加利福尼亚大学董事会 2019-07-12 CN disclosed
CN-110003114-A Diarylhydantoin compounds 加利福尼亚大学董事会 2019-07-12 CN disclosed
CN-110003114-A Diarylhydantoin compounds 加利福尼亚大学董事会 2019-07-12 CN disclosed
US-20190210974-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-07-11 US disclosed
US-20190210974-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-07-11 US disclosed
CN-109790143-A Amine-linked C for target protein degradation3-glutarimide solution stator body C4医药公司 2019-05-21 CN disclosed
US-20190127332-A1 PROCESS FOR THE PREPARATION OF ENZALUTAMIDE LAURUS LABS LIMITED (IN) 2019-05-02 US disclosed
CN-105037273-B Diarylhydantoin compounds 加利福尼亚大学董事会 2019-04-19 CN disclosed
CN-105037273-B Diarylhydantoin compounds 加利福尼亚大学董事会 2019-04-19 CN disclosed
CN-105037273-B Diarylhydantoin compounds 加利福尼亚大学董事会 2019-04-19 CN disclosed
CN-109641874-A C for target protein degradation3The glutarimide degron body of carbon connection C4医药公司 2019-04-16 CN disclosed
CN-109562113-A Spirocyclo-rongeur for target protein degradation C4医药公司 2019-04-02 CN disclosed
CN-109562107-A Heterocyclic degrading ligand for target protein degradation C4医药公司 2019-04-02 CN disclosed
EP-3454862-A1 SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Therapeutics, Inc. (US) 2019-03-20 EP disclosed
EP-3454856-A1 HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Therapeutics, Inc. (US) 2019-03-20 EP disclosed
EP-3455219-A1 AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Therapeutics, Inc. (US) 2019-03-20 EP disclosed
EP-3455218-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Therapeutics, Inc. (US) 2019-03-20 EP disclosed
US-20190076541-A1 HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Theraprutics, Inc. (US) 2019-03-14 US disclosed
US-20190076539-A1 AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Theraprutics, Inc. (US) 2019-03-14 US disclosed
US-20190076542-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Theraprutics, Inc. (US) 2019-03-14 US disclosed
US-20190076540-A1 SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Theraprutics, Inc. (US) 2019-03-14 US disclosed
EP-2991661-B1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE IONIS PHARMACEUTICALS INC (US) 2019-03-13 EP disclosed
EP-3430907-A1 TREATMENT OF BREAST CANCER Medivation Prostate Therapeutics LLC (US) 2019-01-23 EP disclosed
WO-2018237026-A1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2018-12-27 WO disclosed
EP-2906226-B1 MODULATION OF ANDROGEN RECEPTOR EXPRESSION IONIS PHARMACEUTICALS INC (US) 2018-11-21 EP disclosed
US-10131636-B2 Process for the preparation of Enzalutamide LAURUS LABS LIMITED (IN) 2018-11-20 US disclosed
US-10111861-B2 Treatment of breast cancer MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2018-10-30 US disclosed
CN-108658869-A Compound with anti-tumor activity and preparation method thereof and the purposes in pharmacy 复旦大学 2018-10-16 CN disclosed
CN-108658869-A Compound with anti-tumor activity and preparation method thereof and the purposes in pharmacy 复旦大学 2018-10-16 CN disclosed
US-20180245084-A1 COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS IONIS PHARMACEUTICALS, INC. (US) 2018-08-30 US disclosed
EP-2739153-B1 TREATMENT OF BREAST CANCER MEDIVATION PROSTATE THERAPEUTICS LLC (US) 2018-08-22 EP disclosed
CN-108300718-A The adjusting of expression of androgen receptor IONIS制药公司 2018-07-20 CN disclosed
EP-3329775-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS Medivation Prostate Therapeutics LLC (US) 2018-06-06 EP disclosed
EP-3329775-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS Medivation Prostate Therapeutics LLC (US) 2018-06-06 EP disclosed
CN-108064162-A Conjugated antisense compounds and uses thereof IONIS制药公司 2018-05-22 CN disclosed
US-20180086718-A1 Diarylhydantoin Compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-03-29 US disclosed
US-20180086718-A1 Diarylhydantoin Compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-03-29 US disclosed
US-20180086718-A1 Diarylhydantoin Compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-03-29 US disclosed
CN-104703610-B modulation of androgen receptor expression 苏州瑞博生物技术有限公司 2018-03-23 CN disclosed
EP-2538785-B1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS LLC (US) 2018-03-21 EP disclosed
US-9896437-B2 Diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-02-20 US disclosed
US-9896437-B2 Diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-02-20 US disclosed
US-9896437-B2 Diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-02-20 US disclosed
CN-104341351-B A kind of Diarylthiohydantoin derivative and its application 北京海美源医药科技有限公司 2018-02-06 CN disclosed
WO-2018007624-A1 ENZALUTAMIDE DERIVATIVES FOR THE TREATMENT OF PROSTATE AND BREAST CANCER ACTAVIS GROUP PTC EHF (IS) 2018-01-11 WO disclosed
US-20170355727-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE IONIS PHARMACEUTICALS, INC. (US) 2017-12-14 US disclosed
WO-2017197051-A1 AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2017-11-16 WO disclosed
WO-2017197046-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2017-11-16 WO disclosed
WO-2017197036-A1 SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2017-11-16 WO disclosed
WO-2017197055-A1 HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2017-11-16 WO disclosed
US-20170313662-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF ENZALUTAMIDE LAURUS LABS LIMITED (IN) 2017-11-02 US disclosed
US-9682960-B2 Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety ENDORECHERCHE, INC. (CA) 2017-06-20 US disclosed
US-20170158643-A1 PROCESS FOR PREPARATION OF ANDROGEN RECEPTOR ANTAGONIST CADILA HEALTHCARE LIMITED (IN) 2017-06-08 US disclosed
US-20170145424-A1 COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS IONIS PHARMACEUTICALS, INC. (US) 2017-05-25 US disclosed
EP-3151839-A1 COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS Ionis Pharmaceuticals, Inc. (US) 2017-04-12 EP disclosed
US-9611225-B2 Process for preparation of androgen receptor antagonist CADILA HEALTHCARE LIMITED (IN) 2017-04-04 US disclosed
US-20170087132-A1 Treatment of Breast Cancer MEDIVATION PROSTATE THERAPEUTICS LLC 2017-03-30 US disclosed
US-9567588-B2 Modulation of androgen receptor expression IONIS PHARMACEUTICALS, INC. (US) 2017-02-14 US disclosed
EP-3106162-A1 DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR ANTAGONISTS FOR TREATMENT OF CANCER The Regents of the University of California (US) 2016-12-21 EP disclosed
EP-3106162-A1 DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR ANTAGONISTS FOR TREATMENT OF CANCER The Regents of the University of California (US) 2016-12-21 EP disclosed
US-9517229-B2 Treatment of breast cancer MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2016-12-13 US disclosed
EP-3083590-A1 NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY Endorecherche, Inc. (CA) 2016-10-26 EP disclosed
CN-103997894-B The treatment of breast carcinoma 麦迪韦逊前列腺治疗股份有限公司 2016-08-24 CN disclosed
CN-105873917-A Non-steroidal antiandrogens and selective androgen receptor modulators with pyridyl moiety 恩多研究公司 2016-08-17 CN disclosed
CN-103804358-B One class Diarylhydantoin derivant, its preparation method, pharmaceutical composition and application 上海医药集团股份有限公司 2016-06-29 CN disclosed
CN-103804358-B One class Diarylhydantoin derivant, its preparation method, pharmaceutical composition and application 上海医药集团股份有限公司 2016-06-29 CN disclosed
EP-3020706-A1 DIARYLTHIOHYDANTOIN COMPOUNDS USEFUL FOR THE TREATMENT OF A HYPERPROLIFERATIVE DISORDER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-05-18 EP disclosed
EP-2683694-B1 ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF SUZHOU KINTOR PHARMACEUTICALS INC (CN) 2016-04-27 EP disclosed
WO-2016051423-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF ENZALUTAMIDE LAURUS LABS PRIVATE LIMITED (IN) 2016-04-07 WO disclosed
US-20160068846-A1 MODULATION OF ANDROGEN RECEPTOR EXPRESSION ISIS PHARMACEUTICALS INC. (US) 2016-03-10 US disclosed
EP-2991661-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE Ionis Pharmaceuticals, Inc. (US) 2016-03-09 EP disclosed
US-20160017323-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE ISIS PHARMACEUTICALS, INC. (US) 2016-01-21 US disclosed
WO-2015089634-A9 NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY ENDORECHERCHE, INC. (CA) 2016-01-14 WO disclosed
WO-2015188194-A1 COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 2015-12-10 WO disclosed
WO-2015179693-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE ISIS PHARMACEUTICALS, INC. (US) 2015-11-26 WO disclosed
CN-105037273-A Diaryl hydantoin compound UNIV CALIFORNIA 2015-11-11 CN disclosed
US-9181549-B2 Conjugated antisense compounds and their use ISIS PHARMACEUTICALS, INC. (US) 2015-11-10 US disclosed
US-9175291-B2 Modulation of androgen receptor expression ISIS PHARMACEUTICALS INC. (US) 2015-11-03 US disclosed
US-9174943-B2 Processes for the synthesis of diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-11-03 US disclosed
US-9174943-B2 Processes for the synthesis of diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-11-03 US disclosed
US-9174943-B2 Processes for the synthesis of diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-11-03 US disclosed
US-9139565-B2 Histone deacetylase (HDAC) inhibitors targeting prostate tumors and methods of making and using thereof GEORGIA TECH RESEARCH CORPORATION (US) 2015-09-22 US disclosed
CN-103108549-B Method for synthesizing diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-09-09 CN disclosed
CN-103108549-B Method for synthesizing diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-09-09 CN disclosed
CN-103108549-B Method for synthesizing diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-09-09 CN disclosed
US-9126941-B2 Treatment of hyperproliferative disorders with diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-09-08 US disclosed
US-9126941-B2 Treatment of hyperproliferative disorders with diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-09-08 US disclosed
US-9127276-B2 Conjugated antisense compounds and their use ISIS PHARMACEUTICALS, INC. (US) 2015-09-08 US disclosed
US-9126941-B2 Treatment of hyperproliferative disorders with diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-09-08 US disclosed
EP-2906226-A2 MODULATION OF ANDROGEN RECEPTOR EXPRESSION Isis Pharmaceuticals, Inc. (US) 2015-08-19 EP disclosed
US-20150210649-A1 PROCESS FOR PREPARATION OF ANDROGEN RECEPTOR ANTAGONIST ZYDUS LIFESCIENCES LIMITED (IN) 2015-07-30 US disclosed
EP-1893196-B2 DIARYLHYDANTOIN COMPOUND UNIV CALIFORNIA (US) 2015-07-29 EP disclosed
WO-2015089634-A1 NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY ENDORECHERCHE, INC. (CA) 2015-06-25 WO disclosed
US-20150175576-A1 NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY ENDORECHERCHE, INC. (CA) 2015-06-25 US disclosed
CN-104703610-A Modulation of androgen receptor expression ISIS PHARMACEUTICALS INC 2015-06-10 CN disclosed
US-20150126718-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE ISIS PHARMACEUTICALS, INC. (US) 2015-05-07 US disclosed
US-9023879-B2 Specific diarylhydantoin and diarylthiohydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-05-05 US disclosed
US-9023879-B2 Specific diarylhydantoin and diarylthiohydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-05-05 US disclosed
US-9023879-B2 Specific diarylhydantoin and diarylthiohydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2015-05-05 US disclosed
US-20150112082-A1 DIARYLHYDANTOIN COMPOUNDS HOWARD HUGHES MEDICAL INSTITUTE 2015-04-23 US disclosed
US-20150112082-A1 DIARYLHYDANTOIN COMPOUNDS HOWARD HUGHES MEDICAL INSTITUTE 2015-04-23 US disclosed
WO-2015042170-A1 COMPOSITIONS AND USES OF COMBINATIONS OF DIM-RELATED INDOLES AND SELECTED ANTI-ANDROGEN COMPOUNDS WAYNE STATE UNIVERSITY (US) 2015-03-26 WO disclosed
EP-2444085-B1 Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer UNIV CALIFORNIA (US) 2015-03-18 EP disclosed
EP-2444085-B1 Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer UNIV CALIFORNIA (US) 2015-03-18 EP disclosed
US-20150065546-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-03-05 US disclosed
US-20150065546-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-03-05 US disclosed
WO-2015018356-A1 DIARYLHYDANTOIN DERIVATIVE, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF 上海医药集团股份有限公司 (CN) 2015-02-12 WO disclosed
CN-104341396-A Diaryl hydantoin derivative, as well as preparation method, medicine composition and application thereof SHANGHAI PHARMACEUTICALS HOLDING CO LTD 2015-02-11 CN disclosed
CN-104341352-A Diaryl hydantoin compound as androgen receptor antagonist and applications of diaryl hydantoin compound NANJING HENGJIE BIOTECHNOLOGY CO LTD 2015-02-11 CN disclosed
CN-104341351-A Novel diarylthiohydantoin derivative and its application BEIJING HOPE INTERNAT PHARMACEUTICAL TECHNOLOGY DEV CO LTD 2015-02-11 CN disclosed
EP-2397469-B1 Diarylhydantoin compounds UNIV CALIFORNIA (US) 2014-12-31 EP disclosed
EP-2397469-B1 Diarylhydantoin compounds UNIV CALIFORNIA (US) 2014-12-31 EP disclosed
EP-2400847-B1 SPECIFIC DIARYLTHIOHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS INC (US) 2014-12-17 EP disclosed
US-20140343111-A1 DIARYLTHIOHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-11-20 US disclosed
US-20140343123-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE ISIS PHARMACEUTICALS, INC. (US) 2014-11-20 US disclosed
WO-2014179620-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE ISIS PHARMACEUTICALS, INC. (US) 2014-11-06 WO disclosed
EP-2013187-B1 DIARYLTHIOHYDANTOIN COMPOUNDS UNIV CALIFORNIA (US) 2014-10-29 EP disclosed
US-20140296312-A1 TREATMENT OF BREAST CANCER THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2014-10-02 US disclosed
CN-102755318-B Hyperproliferative disorders with diarylhydantoin compounds UNIV CALIFORNIA 2014-09-10 CN disclosed
CN-102755318-B Hyperproliferative disorders with diarylhydantoin compounds UNIV CALIFORNIA 2014-09-10 CN disclosed
EP-2739153-A1 TREATMENT OF BREAST CANCER Medivation Prostate Therapeutics, Inc. (US) 2014-06-11 EP disclosed
CN-103804358-A Biaryl hydantoin derivate and preparation method, medicine composition and application thereof SHANGHAI PHARMACEUTICAL GROUP CO LTD 2014-05-21 CN disclosed
US-8710086-B2 Substituted di-arylhydantoin and di-arylthiohydantoin compounds and methods of use thereof MEDIVATION TECHNOLOGIES, INC. (US) 2014-04-29 US disclosed
US-8710086-B2 Substituted di-arylhydantoin and di-arylthiohydantoin compounds and methods of use thereof MEDIVATION TECHNOLOGIES, INC. (US) 2014-04-29 US disclosed
US-8710086-B2 Substituted di-arylhydantoin and di-arylthiohydantoin compounds and methods of use thereof MEDIVATION TECHNOLOGIES, INC. (US) 2014-04-29 US disclosed
US-8680291-B2 Diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-03-25 US disclosed
US-8680291-B2 Diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-03-25 US disclosed
US-8680291-B2 Diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-03-25 US disclosed
US-8658681-B2 2014-02-25 US disclosed
US-8658681-B2 2014-02-25 US disclosed
US-8658681-B2 2014-02-25 US disclosed
US-8648105-B2 Diarylthiohydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-02-11 US disclosed
US-20140031409-A1 METHODS FOR TREATING ANDROGEN RECEPTOR DEPENDENT DISORDERS INCLUDING CANCERS SANTARIS PHARMA A/S (DK) 2014-01-30 US disclosed
EP-2620432-A3 Diarylhydantoin compounds The Regents Of the University of California (US) 2013-12-18 EP disclosed
EP-2620432-A3 Diarylhydantoin compounds The Regents Of the University of California (US) 2013-12-18 EP disclosed
US-20130331421-A1 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2013-12-12 US disclosed
US-20130331421-A1 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2013-12-12 US disclosed
US-20130289085-A1 HISTONE DEACETYLASE (HDAC) INHIBITORS TARGETING PROSTATE TUMORS AND METHODS OF MAKING AND USING THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2013-10-31 US disclosed
EP-2646553-A1 COMPOSITIONS AND METHODS FOR TREATING ANDROGEN RECEPTOR DEPENDENT DISORDERS INCLUDING CANCERS Santaris Pharma A/S (DK) 2013-10-09 EP disclosed
US-8524755-B2 Specific diarylhydantoin and diarylthiohydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2013-09-03 US disclosed
US-8524755-B2 Specific diarylhydantoin and diarylthiohydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2013-09-03 US disclosed
US-8524755-B2 Specific diarylhydantoin and diarylthiohydantoin compounds MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2013-09-03 US disclosed
EP-2620432-A2 Diarylhydantoin compounds The Regents Of the University of California (US) 2013-07-31 EP disclosed
EP-2620432-A2 Diarylhydantoin compounds The Regents Of the University of California (US) 2013-07-31 EP disclosed
EP-2620432-A2 Diarylhydantoin compounds The Regents Of the University of California (US) 2013-07-31 EP disclosed
US-20130190507-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS LLC 2013-07-25 US disclosed
US-20130190507-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS LLC 2013-07-25 US disclosed
WO-2013066440-A9 TREATMENT OF BREAST CANCER MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2013-07-18 WO disclosed
US-8450290-B2 Methods for treating androgen receptor dependent disorders including cancers ENZON PHARMACEUTICALS, INC. (US) 2013-05-28 US disclosed
CN-103108549-A Method for synthesizing diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS INC 2013-05-15 CN disclosed
CN-103108549-A Method for synthesizing diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS INC 2013-05-15 CN disclosed
CN-103108549-A Method for synthesizing diarylthiohydantoin and diarylhydantoin compounds MEDIVATION PROSTATE THERAPEUTICS INC 2013-05-15 CN disclosed
WO-2013066440-A1 TREATMENT OF BREAST CANCER MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2013-05-10 WO disclosed
WO-2013067142-A1 COMPOUNDS AND TREATMENT METHODS MEDIVATION TECHNOLOGIES, INC. (US) 2013-05-10 WO disclosed
WO-2013067131-A1 TREATMENT METHODS MEDIVATION TECHNOLOGIES, INC. (US) 2013-05-10 WO disclosed
WO-2013067151-A1 TREATMENT METHODS USING DIARYLTHIOHYDANTOIN DERIVATIVES MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2013-05-10 WO disclosed
EP-2561871-A1 Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer The Regents of The University of California (US) 2013-02-27 EP disclosed
EP-2561871-A1 Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer The Regents of The University of California (US) 2013-02-27 EP disclosed
EP-2561871-A1 Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer The Regents of The University of California (US) 2013-02-27 EP disclosed
US-20130034501-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-02-07 US disclosed
US-20130034501-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-02-07 US disclosed
EP-2538785-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS Medivation Prostate Therapeutics, Inc. (US) 2013-01-02 EP disclosed
EP-2538785-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS Medivation Prostate Therapeutics, Inc. (US) 2013-01-02 EP disclosed
US-20120295944-A1 TREATMENT OF HYPERPROLIFERATIVE DISORDERS WITH DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-11-22 US disclosed
US-20120295944-A1 TREATMENT OF HYPERPROLIFERATIVE DISORDERS WITH DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-11-22 US disclosed
CN-102755318-A Hyperproliferative disorders with diarylhydantoin compounds UNIV CALIFORNIA 2012-10-31 CN disclosed
CN-102755318-A Hyperproliferative disorders with diarylhydantoin compounds UNIV CALIFORNIA 2012-10-31 CN disclosed
US-20120251551-A1 Substituted (Heteroarylmethyl)thiohydantoins BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-10-04 US disclosed
CN-101460467-B Diarylthiohydantoin compounds UNIV CALIFORNIA 2012-09-19 CN disclosed
CN-102639523-A Substituted (heteroarylmethyl) thiohydantoin useful as anticancer agents BAYER SCHERING PHARMA AG 2012-08-15 CN disclosed
EP-2400847-A4 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS INC (US) 2012-08-08 EP disclosed
US-20120190718-A1 DIARYLTHIOHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-07-26 US disclosed
US-20120184580-A1 SUBSTITUTED DI-ARYLHYDANTOIN AND DI-ARYLTHIOHYDANTOIN COMPOUNDS AND METHODS OF USE THEREOF MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2012-07-19 US disclosed
US-20120184580-A1 SUBSTITUTED DI-ARYLHYDANTOIN AND DI-ARYLTHIOHYDANTOIN COMPOUNDS AND METHODS OF USE THEREOF MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2012-07-19 US disclosed
EP-2475653-A1 SUSTITUTED ( HETEROARYLMETHYL ) THIOHYDANTOINS AS ANTICANCER DRUGS Bayer Pharma Aktiengesellschaft (DE) 2012-07-18 EP disclosed
CN-102584712-A Diarylhydantoin compounds UNIV CALIFORNIA 2012-07-18 CN disclosed
CN-102584712-A Diarylhydantoin compounds UNIV CALIFORNIA 2012-07-18 CN disclosed
CN-102584712-A Diarylhydantoin compounds UNIV CALIFORNIA 2012-07-18 CN disclosed
US-8183274-B2 Treatment of hyperproliferative disorders with diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-22 US disclosed
US-8183274-B2 Treatment of hyperproliferative disorders with diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-22 US disclosed
US-8183274-B2 Treatment of hyperproliferative disorders with diarylhydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-22 US disclosed
WO-2012065051-A1 COMPOSITIONS AND METHODS FOR TREATING ANDROGEN RECEPTOR DEPENDENT DISORDERS INCLUDING CANCERS ENZON PHARMACEUTICALS, INC. (US) 2012-05-18 WO disclosed
EP-2444085-A1 Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer The Regents of The University of California (US) 2012-04-25 EP disclosed
EP-2444085-A1 Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer The Regents of The University of California (US) 2012-04-25 EP disclosed
EP-2444085-A1 Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer The Regents of The University of California (US) 2012-04-25 EP disclosed
WO-2012050868-A1 HISTONE DEACETYLASE (HDAC) INHIBITORS TARGETING PROSTATE TUMORS AND METHODS OF MAKING AND USING THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2012-04-19 WO disclosed
CN-102421291-A Specific diarylhydantoin and diarylthiohydantoin compounds MEDIVATION PROSTATE THERAPEUTICS INC 2012-04-18 CN disclosed
CN-102421291-A Specific diarylhydantoin and diarylthiohydantoin compounds MEDIVATION PROSTATE THERAPEUTICS INC 2012-04-18 CN disclosed
CN-101222922-B Diarylhydantoin compounds UNIV CALIFORNIA 2012-04-18 CN disclosed
CN-101222922-B Diarylhydantoin compounds UNIV CALIFORNIA 2012-04-18 CN disclosed
CN-101222922-B Diarylhydantoin compounds UNIV CALIFORNIA 2012-04-18 CN disclosed
CN-102421291-A Specific diarylhydantoin and diarylthiohydantoin compounds MEDIVATION PROSTATE THERAPEUTICS INC 2012-04-18 CN disclosed
EP-2416657-A1 SUBSTITUTED DI-ARYLHYDANTOIN AND DI-ARYLTHIOHYDANTOIN COMPOUNDS AND METHODS FOR USE THEREOF Medivation Prostate Therapeutics, Inc. (US) 2012-02-15 EP disclosed
EP-2416657-A1 SUBSTITUTED DI-ARYLHYDANTOIN AND DI-ARYLTHIOHYDANTOIN COMPOUNDS AND METHODS FOR USE THEREOF Medivation Prostate Therapeutics, Inc. (US) 2012-02-15 EP disclosed
US-20120035231-A1 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS LLC 2012-02-09 US disclosed
US-20120035231-A1 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS LLC 2012-02-09 US disclosed
US-8110594-B2 Diarylthiohydantoin compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-02-07 US disclosed
EP-1893196-B1 DIARYLHYDANTOIN COMPOUND UNIV CALIFORNIA (US) 2012-01-18 EP disclosed
EP-1893196-B1 DIARYLHYDANTOIN COMPOUND UNIV CALIFORNIA (US) 2012-01-18 EP disclosed
EP-2400847-A1 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS Medivation Prostate Therapeutics, Inc. (US) 2012-01-04 EP disclosed
EP-2400847-A1 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS Medivation Prostate Therapeutics, Inc. (US) 2012-01-04 EP disclosed
EP-2397469-A1 Diarylhydantoin compounds The Regents Of the University of California (US) 2011-12-21 EP disclosed
EP-2397469-A1 Diarylhydantoin compounds The Regents Of the University of California (US) 2011-12-21 EP disclosed
EP-2397469-A1 Diarylhydantoin compounds The Regents Of the University of California (US) 2011-12-21 EP disclosed
WO-2011106570-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2011-09-01 WO disclosed
WO-2011106570-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2011-09-01 WO disclosed
US-20110152348-A1 METHODS FOR TREATING ANDROGEN RECEPTOR DEPENDENT DISORDERS INCLUDING CANCERS ENZON PHARMACEUTICALS, INC. (US) 2011-06-23 US disclosed
WO-2011029537-A1 SUSTITUTED ( HETEROARYLMETHYL ) THIOHYDANTOINS AS ANTICANCER DRUGS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-03-17 WO disclosed
WO-2010118354-A1 SUBSTITUTED DI-ARYLHYDANTOIN AND DI-ARYLTHIOHYDANTOIN COMPOUNDS AND METHODS FOR USE THEREOF MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2010-10-14 WO disclosed
WO-2010118354-A1 SUBSTITUTED DI-ARYLHYDANTOIN AND DI-ARYLTHIOHYDANTOIN COMPOUNDS AND METHODS FOR USE THEREOF MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2010-10-14 WO disclosed
WO-2010099238-A1 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2010-09-02 WO disclosed
WO-2010099238-A1 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS MEDIVATION PROSTATE THERAPEUTICS, INC. (US) 2010-09-02 WO disclosed
EP-2220050-A2 DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS The Regents Of The University Of California (US) 2010-08-25 EP disclosed
EP-2220050-A2 DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS The Regents Of The University Of California (US) 2010-08-25 EP disclosed
US-20100210665-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-19 US disclosed
US-20100210665-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-19 US disclosed
US-20100172975-A1 TREATMENT OF HYPERPROLIFERATIVE DISORDERS WITH DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-08 US disclosed
US-20100172975-A1 TREATMENT OF HYPERPROLIFERATIVE DISORDERS WITH DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-08 US disclosed
US-7709517-B2 N-methyl-4-{4-[7-(4-cyano-3 -trifluoromethylphenyl)-6,8-dioxo-5,7-diazaspiro[3.4]oct-5-yl]-phenyl}butyramide; for treatment of hormone refractory prostate cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-05-04 US disclosed
US-7709517-B2 N-methyl-4-{4-[7-(4-cyano-3 -trifluoromethylphenyl)-6,8-dioxo-5,7-diazaspiro[3.4]oct-5-yl]-phenyl}butyramide; for treatment of hormone refractory prostate cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-05-04 US disclosed
US-7709517-B2 N-methyl-4-{4-[7-(4-cyano-3 -trifluoromethylphenyl)-6,8-dioxo-5,7-diazaspiro[3.4]oct-5-yl]-phenyl}butyramide; for treatment of hormone refractory prostate cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-05-04 US disclosed
CN-101460467-A Diarylthiohydantoin compounds UNIV CALIFORNIA (US) 2009-06-17 CN disclosed
WO-2009055053-A3 DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS UNIV CALIFORNIA (US) 2009-06-11 WO disclosed
US-20090111864-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-30 US disclosed
US-20090111864-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-30 US disclosed
WO-2009055053-A2 DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-30 WO disclosed
WO-2009055053-A2 DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-30 WO disclosed
EP-1893196-A4 DIARYLHYDANTOIN COMPOUNDS UNIV CALIFORNIA (US) 2009-03-18 EP disclosed
EP-1893196-A4 DIARYLHYDANTOIN COMPOUNDS UNIV CALIFORNIA (US) 2009-03-18 EP disclosed
EP-2013187-A2 DIARYLTHIOHYDANTOIN COMPOUNDS The Regents of the University of California (US) 2009-01-14 EP disclosed
CN-101222922-A Diarylhydantoin compounds UNIV CALIFORNIA (US) 2008-07-16 CN disclosed
CN-101222922-A Diarylhydantoin compounds UNIV CALIFORNIA (US) 2008-07-16 CN disclosed
CN-101222922-A Diarylhydantoin compounds UNIV CALIFORNIA (US) 2008-07-16 CN disclosed
US-20080139634-A2 Use against hormone refractory prostate cancer; 1-(3-trifluoromethyl-4-cyanophenyl)-2-thioxo-3-(substituted phenyl)-imidazolidin-5-one and spiro ring derivatives thereof; androgen receptor antagonists with minimal agonist activity REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-06-12 US disclosed
WO-2007127010-A9 DIARYLTHIOHYDANTOIN COMPOUNDS UNIV CALIFORNIA (US) 2008-05-22 WO disclosed
EP-1893196-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-05 EP disclosed
EP-1893196-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-05 EP disclosed
WO-2007129184-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF PHENYTOIN SODIUM ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) 2007-11-15 WO disclosed
WO-2007127010-A2 DIARYLTHIOHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-11-08 WO disclosed
US-20070254933-A1 Use against hormone refractory prostate cancer; 1-(3-trifluoromethyl-4-cyanophenyl)-2-thioxo-3-(substituted phenyl)-imidazolidin-5-one and spiro ring derivatives thereof; selective androgen receptor modulators; non-steroidal, non-toxic, and tissue selective REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-11-01 US disclosed
US-20070004753-A1 N-methyl-4-{4-[7-(4-cyano-3 -trifluoromethylphenyl)-6,8-dioxo-5,7-diazaspiro[3.4]oct-5-yl]-phenyl}butyramide; for treatment of hormone refractory prostate cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-01-04 US disclosed
US-20070004753-A1 N-methyl-4-{4-[7-(4-cyano-3 -trifluoromethylphenyl)-6,8-dioxo-5,7-diazaspiro[3.4]oct-5-yl]-phenyl}butyramide; for treatment of hormone refractory prostate cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-01-04 US disclosed
US-20070004753-A1 N-methyl-4-{4-[7-(4-cyano-3 -trifluoromethylphenyl)-6,8-dioxo-5,7-diazaspiro[3.4]oct-5-yl]-phenyl}butyramide; for treatment of hormone refractory prostate cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-01-04 US disclosed
WO-2006124118-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-11-23 WO disclosed
WO-2006124118-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-11-23 WO disclosed
WO-1998034610-A1 COMPOSITION FOR IMPROVING HAIR REGROWTH AND METHOD OF USE GROTON ROBERT B (US) 1998-08-13 WO disclosed
EP-0232311-B1 TOPICAL COMPOSITION AND METHOD FOR STIMULATING HAIR GROWTH PROCTOR, Peter H. (US) 1993-05-12 EP disclosed
EP-0192660-B1 ABSORPTION ENHANCING AGENTS SURVIVAL TECHNOLOGY, INC. (US) 1992-11-19 EP disclosed
WO-1991015235-A1 t-PA ENHANCER PROFILE SURVIVAL TECHNOLOGY, INC. (US) 1991-10-17 WO disclosed
US-5002930-A Hydroxyamine, Alkylamine, Hydroxyalkylamine SURVIVAL TECHNOLOGY, INC. (US) 1991-03-26 US disclosed
EP-0383092-A2 Chromogenic merocyanine enzyme substrates Bayer Corporation (US) 1990-08-22 EP disclosed
US-RE32919-E TISSUE-TYPE PLASMINOGEN ACTIVATOR SURVIVAL TECHNOLOGY, INC. (US) 1989-05-09 US disclosed
EP-0214281-A4 PROTEIN ABSORPTION ENHANCING AGENTS. SURVIVAL TECHNOLOGY (US) 1989-03-16 EP disclosed
US-4772585-A Protein thrombolytic agent with absorption enhancing agent SURVIVAL TECHNOLOGY, INC. (US) 1988-09-20 US disclosed
US-4661469-A HYDROXYLAMINE, HYDROXYLAMINE HYDROCHLORIDE DISASSOCIATING AGENT SURVIVAL TECHNOLOGY, INC. (US) 1987-04-28 US disclosed
US-4656034-A PREVENTING CYTOLYSIS SURVIVAL TECHNOLOGY, INC. (US) 1987-04-07 US disclosed
EP-0214281-A1 PROTEIN ABSORPTION ENHANCING AGENTS. SURVIVAL TECHNOLOGY (US) 1987-03-18 EP disclosed
EP-0191814-A4 PROTEIN ABSORPTION ENHANCING AGENTS. SURVIVAL TECHNOLOGY (US) 1987-03-16 EP disclosed
WO-1986005095-A1 t-PA COMPOSITION AND METHOD OF GETTING INTO BLOOD STREAM SURVIVAL TECHNOLOGY, INC. (US) 1986-09-12 WO disclosed
WO-1986005096-A1 PROTEIN ABSORPTION ENHANCING AGENTS SURVIVAL TECHNOLOGY, INC. (US) 1986-09-12 WO disclosed
EP-0191814-A1 PROTEIN ABSORPTION ENHANCING AGENTS. SURVIVAL TECHNOLOGY (US) 1986-08-27 EP disclosed
EP-0191056-A1 t-PA COMPOSITION AND METHOD OF GETTING INTO BLOOD STREAM SURVIVAL TECHNOLOGY, INC. (US) 1986-08-20 EP disclosed
WO-1986001104-A1 t-PA COMPOSITION AND METHOD OF GETTING INTO BLOOD STREAM SURVIVAL TECHNOLOGY, INC. (US) 1986-02-27 WO disclosed
WO-1986001109-A1 PROTEIN ABSORPTION ENHANCING AGENTS SURVIVAL TECHNOLOGY, INC. (US) 1986-02-27 WO disclosed
US-4514382-A IMIDAZOLE DERIVATIVE COLGATE-PALMOLIVE COMPANY (US) 1985-04-30 US disclosed
US-4514382-A IMIDAZOLE DERIVATIVE COLGATE-PALMOLIVE COMPANY (US) 1985-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152348-A1 METHODS FOR TREATING ANDROGEN RECEPTOR DEPENDENT DISORDERS INCLUDING CANCERS AR, ESRRB, ESRRA MMP2 3084/4885MMP9 3476/4885MMP3 1559/4885
US-20240132452-A1 DIARYLHYDANTOIN COMPOUNDS BPHL, AR, SHBG MMP2 1767/4885MMP9 1537/4885MMP3 755/4885
US-20230372496-A1 TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS CRBN, CDR2, MDM2 MMP2 3270/4885MMP9 4169/4885MMP3 3978/4885
US-20120295944-A1 TREATMENT OF HYPERPROLIFERATIVE DISORDERS WITH DIARYLHYDANTOIN COMPOUNDS CDK4, CCNH, VHL MMP2 3609/4885MMP9 3503/4885MMP3 1713/4885
US-20120184580-A1 SUBSTITUTED DI-ARYLHYDANTOIN AND DI-ARYLTHIOHYDANTOIN COMPOUNDS AND METHODS OF USE THEREOF AR, BRDT, AADAC MMP2 3236/4885MMP9 4034/4885MMP3 2464/4885
US-10849982-B2 C3-carbon linked glutarimide degronimers for target protein degradation STUB1, UBE3C, UBE3A MMP2 3400/4885MMP9 4220/4885MMP3 2649/4885
US-20080139634-A2 Use against hormone refractory prostate cancer; 1-(3-trifluoromethyl-4-cyanophenyl)-2-thioxo-3-(substituted phenyl)-imidazolidin-5-one and spiro ring derivatives thereof; androgen receptor antagonists with minimal agonist activity AR, LHCGR, KLK3 MMP2 3134/4885MMP9 3401/4885MMP3 1977/4885
US-20120251551-A1 Substituted (Heteroarylmethyl)thiohydantoins TPMT, BPHL, VHL MMP2 1913/4885MMP9 2106/4885MMP3 1377/4885
US-20170313662-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF ENZALUTAMIDE KLK4, KLK5, KLK1 MMP2 1014/4885MMP9 1573/4885MMP3 1687/4885
US-20070254933-A1 Use against hormone refractory prostate cancer; 1-(3-trifluoromethyl-4-cyanophenyl)-2-thioxo-3-(substituted phenyl)-imidazolidin-5-one and spiro ring derivatives thereof; selective androgen receptor modulators; non-steroidal, non-toxic, and tissue selective AR, NR5A1, SHBG MMP2 2664/4885MMP9 2435/4885MMP3 1222/4885
US-20230014124-A1 HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION CRBN, MDM2, STUB1 MMP2 4602/4885MMP9 4688/4885MMP3 4575/4885
US-20190127332-A1 PROCESS FOR THE PREPARATION OF ENZALUTAMIDE KLK4, KLK5, KLK1 MMP2 937/4885MMP9 1600/4885MMP3 1607/4885
US-20180086718-A1 Diarylhydantoin Compounds BPHL, AR, SHBG MMP2 1767/4885MMP9 1537/4885MMP3 755/4885
US-20130331421-A1 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS BPHL, PARK7, APP MMP2 2313/4885MMP9 1862/4885MMP3 1796/4885
US-11185592-B2 Spirocyclic degronimers for target protein degradation STUB1, UBE3C, UBE3A MMP2 3658/4885MMP9 4168/4885MMP3 3440/4885
US-20070004753-A1 N-methyl-4-{4-[7-(4-cyano-3 -trifluoromethylphenyl)-6,8-dioxo-5,7-diazaspiro[3.4]oct-5-yl]-phenyl}butyramide; for treatment of hormone refractory prostate cancer AR, BRDT, GNRHR MMP2 3246/4885MMP9 2043/4885MMP3 1851/4885
US-20210106688-A1 SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION STUB1, UBE3C, UBE3A MMP2 3658/4885MMP9 4168/4885MMP3 3440/4885
US-20140031409-A1 METHODS FOR TREATING ANDROGEN RECEPTOR DEPENDENT DISORDERS INCLUDING CANCERS AR, ESRRB, ESRRA MMP2 3084/4885MMP9 3476/4885MMP3 1559/4885
US-20210054017-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE GNE, FUT6, GALNT13 MMP2 2794/4885MMP9 4209/4885MMP3 3591/4885
US-10626091-B2 Process for the preparation of enzalutamide KLK4, KLK5, KLK1 MMP2 937/4885MMP9 1600/4885MMP3 1607/4885
US-20100172975-A1 TREATMENT OF HYPERPROLIFERATIVE DISORDERS WITH DIARYLHYDANTOIN COMPOUNDS CDK4, CCNH, VHL MMP2 3609/4885MMP9 3503/4885MMP3 1713/4885
US-20130289085-A1 HISTONE DEACETYLASE (HDAC) INHIBITORS TARGETING PROSTATE TUMORS AND METHODS OF MAKING AND USING THEREOF HDAC1, HDAC11, HDAC3 MMP2 442/4885MMP9 655/4885MMP3 260/4885
US-20150065546-A1 DIARYLHYDANTOIN COMPOUNDS BPHL, ACP3, AR MMP2 989/4885MMP9 1009/4885MMP3 420/4885
US-20130190507-A1 PROCESSES FOR THE SYNTHESIS OF DIARYLTHIOHYDANTOIN AND DIARYLHYDANTOIN COMPOUNDS BPHL, PTMS, DHPS MMP2 2752/4885MMP9 2816/4885MMP3 2467/4885
US-20190210974-A1 DIARYLHYDANTOIN COMPOUNDS BPHL, AR, SHBG MMP2 1767/4885MMP9 1537/4885MMP3 755/4885
US-20180245084-A1 COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS SI, FABP2, GNE MMP2 1435/4885MMP9 2304/4885MMP3 2543/4885
US-10646575-B2 Heterocyclic degronimers for target protein degradation CRBN, MDM2, STUB1 MMP2 4602/4885MMP9 4688/4885MMP3 4575/4885
US-20190262315-A1 Treatment of Breast Cancer BRCA1, TP53, TUBB6 MMP2 1614/4885MMP9 2690/4885MMP3 880/4885
US-11992531-B2 C3-carbon linked glutarimide degronimers for target protein degradation STUB1, UBE3C, UBE3A MMP2 3400/4885MMP9 4220/4885MMP3 2649/4885
US-10570169-B2 Conjugated antisense compounds and their use GNE, GALNT1, GALNT6 MMP2 2480/4885MMP9 3846/4885MMP3 3123/4885
US-10660968-B2 Spirocyclic degronimers for target protein degradation STUB1, UBE3C, UBE3A MMP2 3658/4885MMP9 4168/4885MMP3 3440/4885
US-10905768-B1 Heterocyclic degronimers for target protein degradation CRBN, MDM2, STUB1 MMP2 4602/4885MMP9 4688/4885MMP3 4575/4885
US-20120035231-A1 SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS BPHL, PARK7, APP MMP2 2313/4885MMP9 1862/4885MMP3 1796/4885
US-20170158643-A1 PROCESS FOR PREPARATION OF ANDROGEN RECEPTOR ANTAGONIST AR, AVPR2, AVPR1A MMP2 2239/4885MMP9 3077/4885MMP3 1117/4885
US-20170087132-A1 Treatment of Breast Cancer BRCA1, MKI67, BAX MMP2 125/4885MMP9 617/4885MMP3 412/4885
US-20230095223-A1 SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION STUB1, UBE3C, UBE3A MMP2 3658/4885MMP9 4168/4885MMP3 3440/4885
US-20200157548-A1 COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS SI, FABP2, GNE MMP2 1435/4885MMP9 2304/4885MMP3 2543/4885
US-20200079741-A1 DIARYLHYDANTOIN COMPOUNDS BPHL, AR, SHBG MMP2 1767/4885MMP9 1537/4885MMP3 755/4885
US-10131636-B2 Process for the preparation of Enzalutamide KLK4, KLK5, KLK1 MMP2 937/4885MMP9 1600/4885MMP3 1607/4885
US-20150112082-A1 DIARYLHYDANTOIN COMPOUNDS BPHL, AR, SHBG MMP2 1767/4885MMP9 1537/4885MMP3 755/4885
US-20190076539-A1 AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION GCGR, STUB1, GID4 MMP2 3664/4885MMP9 4300/4885MMP3 3500/4885
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION STUB1, MDM2, USP30 MMP2 2558/4885MMP9 2331/4885MMP3 2404/4885
US-20190076540-A1 SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION STUB1, UBE3C, UBE3A MMP2 3658/4885MMP9 4168/4885MMP3 3440/4885
US-20140296312-A1 TREATMENT OF BREAST CANCER BRCA1, BAX, BAD MMP2 131/4885MMP9 623/4885MMP3 422/4885
US-20090111864-A1 DIARYLHYDANTOIN COMPOUNDS BPHL, ACP3, AR MMP2 989/4885MMP9 1009/4885MMP3 420/4885
US-20120190718-A1 DIARYLTHIOHYDANTOIN COMPOUNDS AR, SHBG, PTMS MMP2 3208/4885MMP9 2853/4885MMP3 1700/4885
US-20190076541-A1 HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION CRBN, MDM2, STUB1 MMP2 4602/4885MMP9 4688/4885MMP3 4575/4885
US-20130034501-A1 DIARYLHYDANTOIN COMPOUNDS FAP, LEF1, LPXN MMP2 794/4885MMP9 795/4885MMP3 217/4885
US-10111861-B2 Treatment of breast cancer BRCA1, MKI67, BAX MMP2 125/4885MMP9 617/4885MMP3 412/4885
US-20170145424-A1 COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS SI, FABP2, GNE MMP2 1435/4885MMP9 2304/4885MMP3 2543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.