Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Idroxioleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.53 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.50 |
| ▸ | FABP3 | P05413 | 7/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Idroxioleic Acid SCHEMBL16004901 | 1.00 | FABP3 (0.56) | FABP3CA2GPR84FFAR1FFAR4 | |
| Idroxioleic Acid SCHEMBL20573728 | 0.97 | FABP3 (0.59) | FABP3GPR84FFAR1FFAR4FAAH | |
| Ibrilatazar SCHEMBL20573582 | 0.95 | FABP3 (0.59) | FABP3FFAR1FFAR4 | |
| Idroxioleic Acid SCHEMBL1537785 | 0.93 | FABP3 (0.53) | FABP3GPR84FFAR1FFAR4FAAH | |
| Idroxioleic Acid SCHEMBL1537782 | 0.93 | FABP3 (0.53) | FABP3GPR84FFAR1FFAR4FAAH | |
| Ibrilatazar SCHEMBL20573719 | 0.92 | FABP3 (0.62) | FABP3FFAR1FFAR4 | |
| Oleic Acid SCHEMBL8527395 | 0.89 | FABP3 (0.71) | FABP3FFAR1FFAR4FAAH | |
| Oleic Acid SCHEMBL8527405 | 0.89 | FABP3 (0.71) | FABP3FFAR1FFAR4FAAH | |
| SCHEMBL10913274 | 0.89 | CA2 (0.64) | CA2GPR84FFAR1FFAR4CA1 | |
| SCHEMBL9355567 | 0.89 | CA2 (0.64) | CA2GPR84FFAR1FFAR4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117861857-A | Phosphogypsum deep impurity removal method based on flotation separation and phase regulation | 湖南科技大学 | 2024-04-12 | — | — | CN | claimed |
| CN-114377860-A | Resource utilization method of titanium dioxide chlorination dust collection slag by chlorination process | 宜宾天原海丰和泰有限公司 | 2022-04-22 | — | — | CN | claimed |
| US-20140288176-A1 | ENANTIOMERS OF 2-HYDROXY DERIVATIVES OF FATTY ACIDS | UNIVERSITAT DE LES ILLES BALEARS (ES) | 2014-09-25 | — | — | US | claimed |
| EP-2774910-A1 | ENANTIOMERS OF 2-HYDROXY DERIVATIVES OF FATTY ACIDS | Universitat de les Illes Balears (ES) | 2014-09-10 | — | — | EP | claimed |
| US-20250387792-A1 | COMPOSITIONS AND METHODS FOR FROTH MODIFICATION | ECOLAB USA INC (US) | 2025-12-25 | — | — | US | disclosed |
| CN-115487933-B | Method for separating and recycling black slag of titanium dioxide ore coke by using chlorination process | 河南佰利联新材料有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-118106128-A | Petroleum coke collecting agent and application thereof | 龙佰四川矿冶有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-117861857-A | Phosphogypsum deep impurity removal method based on flotation separation and phase regulation | 湖南科技大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-115487933-A | Method for separating and recycling coke black slag of titanium white fine ore by chlorination process | 河南佰利联新材料有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-110612161-B | Improved composition and process for reverse froth flotation of phosphate ores | 埃科莱布美国股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114377860-A | Resource utilization method of titanium dioxide chlorination dust collection slag by chlorination process | 宜宾天原海丰和泰有限公司 | 2022-04-22 | — | — | CN | disclosed |
| US-20200338571-A1 | COMPOSITIONS AND METHODS FOR REVERSE FROTH FLOTATION OF PHOSPHATE ORES | ECOLAB USA INC. | 2020-10-29 | — | — | US | disclosed |
| US-10737281-B2 | Compositions and methods for reverse froth flotation of phosphate ores | ECOLAB USA INC. (US) | 2020-08-11 | — | — | US | disclosed |
| CN-110612161-A | Improved composition and process for reverse froth flotation of phosphate ores | 埃科莱布美国股份有限公司 | 2019-12-24 | — | — | CN | disclosed |
| US-20180345297-A1 | COMPOSITIONS AND METHODS FOR REVERSE FROTH FLOTATION OF PHOSPHATE ORES | ECOLAB USA INC. | 2018-12-06 | — | — | US | disclosed |
| US-8252276-B2 | Cyclodextrin-based polymers for therapeutics delivery | CERULEAN PHARMA INC. (US) | 2012-08-28 | — | — | US | disclosed |
| WO-2011089265-A1 | USE OF FATTY ACID COMPOUNDS FOR LOWERING BLOOD GLUCOSE LEVELS | BRIDGE BIORESEARCH PLC (GB) | 2011-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288176-A1 | ENANTIOMERS OF 2-HYDROXY DERIVATIVES OF FATTY ACIDS | SCD, ELOVL1, ELOVL3 | CA2 198/4885CA1 1596/4885FABP3 175/4885 |
| US-20250387792-A1 | COMPOSITIONS AND METHODS FOR FROTH MODIFICATION | MAFG, FRG1, LIPG | CA2 516/4885CA1 537/4885FABP3 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.