SCHEMBL2275857

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2269563	0.88	STK39 (0.57)	SERPINE1STK39PRSS12SLC16A3PYGL
	SCHEMBL2270366	0.85	STK39 (0.47)	SERPINE1STK39HDAC1HDAC8HDAC6
	SCHEMBL2274965	0.85	L3MBTL1 (0.49)	SERPINE1CYP2C9CYP2C19MEN1KMT2A
	SCHEMBL2270119	0.84	PPARG (0.64)	SERPINE1STK39PYGLPYGMMEN1
	SCHEMBL2270287	0.82	PYGM (0.70)	SERPINE1PRSS12HDAC1HDAC8HDAC6
	SCHEMBL2273564	0.82	HDAC1 (0.61)	SERPINE1PRSS12HDAC1HDAC8HDAC6
	SCHEMBL2271588	0.82	SERPINE1 (0.64)	SERPINE1PYGLPYGMMEN1KMT2A
	SCHEMBL2275201	0.82	ACLY (0.67)	SERPINE1STK39PRSS12PYGLPYGM
	SCHEMBL2272043	0.82	SERPINE1 (0.75)	SERPINE1PRSS12HDAC1HDAC8HDAC6
	SCHEMBL2270449	0.81	PYGM (0.56)	SERPINE1HDAC1HDAC8HDAC6PYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.