Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 14/20 | 0.69 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.67 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.66 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.66 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.64 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.64 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.64 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.64 |
| ▸ | LDHA | P00338 | 1/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.64 |
| ▸ | FBP1 | P09467 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.64 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.64 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198136 | 1.00 | DNPH1 (0.69) | DNPH1P2RY12TAS1R3TAS1R1P2RY2 | |
| SCHEMBL23780814 | 1.00 | DNPH1 (0.69) | DNPH1P2RY12TAS1R3TAS1R1P2RY2 | |
| SCHEMBL23787292 | 1.00 | DNPH1 (0.69) | DNPH1P2RY12TAS1R3TAS1R1P2RY2 | |
| SCHEMBL23787291 | 1.00 | DNPH1 (0.69) | DNPH1P2RY12TAS1R3TAS1R1P2RY2 | |
| SCHEMBL23780815 | 0.86 | ADORA3 (0.66) | ADORA1SMN1; SMN2 | |
| SCHEMBL23780820 | 0.86 | ADORA3 (0.66) | ADORA1SMN1; SMN2 | |
| SCHEMBL23780816 | 0.86 | ADORA3 (0.66) | ADORA1SMN1; SMN2 | |
| SCHEMBL23787289 | 0.86 | ADORA3 (0.66) | ADORA1SMN1; SMN2 | |
| SCHEMBL23787290 | 0.86 | ADORA3 (0.66) | ADORA1SMN1; SMN2 | |
| SCHEMBL23780819 | 0.86 | ADORA3 (0.66) | ADORA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534439-B2 | Xanthohumol derivatives and methods for making and using | OREGON STATE UNIVERSITY (US) | 2026-01-27 | — | — | US | disclosed |
| US-20250362309-A1 | BIOMARKERS AND USE THEREOF FOR DIAGNOSIS, PREVENTION, AND TREATMENT OF MUSCLE ATROPHY | MYOMAR MOLECULAR INC. (CA) | 2025-11-27 | — | — | US | disclosed |
| WO-2025072741-A1 | PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-04-03 | — | — | WO | disclosed |
| CN-118726428-A | Preparation method of adenylyl succinic acid | 华东理工大学 | 2024-10-01 | — | — | CN | disclosed |
| US-20240051922-A1 | XANTHOHUMOL DERIVATIVES AND METHODS FOR MAKING AND USING | OREGON STATE UNIVERSITY (US) | 2024-02-15 | — | — | US | disclosed |
| US-20230158084-A1 | PROBIOTICS, METABOLITES, AND USES THEREOF | HERITAGE MEDICAL RESEARCH INSTITUTE | 2023-05-25 | — | — | US | disclosed |
| US-11273161-B2 | Methods of treating autism spectrum disorders | THE BROAD INSTITUTE, INC. (US) | 2022-03-15 | — | — | US | disclosed |
| US-20210277005-A1 | PROANGIOGENIC COMPOSITIONS AND METHODS OF USE | UNIVERSITY OF NORTH DAKOTA | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534439-B2 | Xanthohumol derivatives and methods for making and using | MT-CO1, MT-CO2, PC | DNPH1 2745/4885P2RY12 962/4885TAS1R3 513/4885 |
| US-11273161-B2 | Methods of treating autism spectrum disorders | GABBR1, CHAT, GABBR2 | DNPH1 3434/4885P2RY12 3664/4885TAS1R3 627/4885 |
| US-20210277005-A1 | PROANGIOGENIC COMPOSITIONS AND METHODS OF USE | PGF, HDGF, VEGFA | DNPH1 3315/4885P2RY12 1469/4885TAS1R3 3856/4885 |
| US-20240051922-A1 | XANTHOHUMOL DERIVATIVES AND METHODS FOR MAKING AND USING | XDH, PC, TFB2M | DNPH1 1003/4885P2RY12 1923/4885TAS1R3 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.