SCHEMBL253545

SCHEMBL253545

CCc1nc2cc(OC)c(Oc3ccc4c(c3)OC(F)(F)C(F)(F)O4)cc2c(OC(=O)OC)c1C

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDR P35968 16/20 0.36
LCK P06239 11/20 0.36
MET P08581 10/20 0.36
ALDH1A1 P00352 1/20 0.35
TEK Q02763 8/20 0.34
AURKA O14965 3/20 0.34
AURKB Q96GD4 2/20 0.34
SLC10A2 Q12908 1/20 0.33
CSF1R P07333 1/20 0.33
PDGFRB P09619 1/20 0.33
FLT3 P36888 1/20 0.33
LYN P07948 1/20 0.33
FLT1 P17948 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30356348 1.00 KDR (0.36) KDRLCKMETALDH1A1TEK
SCHEMBL30356307 0.93 PDE10A (0.34) KDRLCKMETALDH1A1TEK
SCHEMBL326170 0.93 PDE10A (0.34) KDRLCKMETALDH1A1TEK
SCHEMBL16013116 0.89 KDR (0.35) KDRLCKMETALDH1A1TEK
SCHEMBL2446404 0.85 KDR (0.33) KDRLCKMETALDH1A1TEK
SCHEMBL250753 0.84 ALDH1A1 (0.34) KDRLCKMETALDH1A1TEK
SCHEMBL2446405 0.82 ALDH1A1 (0.33) KDRLCKMETALDH1A1TEK
SCHEMBL15929951 0.77 ALDH1A1 (0.45) KDRALDH1A1
SCHEMBL12479430 0.75 SLC10A2 (0.31) SLC10A2
SCHEMBL29627713 0.73 ALDH1A1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160037775-A1 ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-11 US claimed
EP-2582242-A1 ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDE AND ACARICIDE PROPERTIES Bayer Intellectual Property GmbH (DE) 2013-04-24 EP claimed
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2011-12-22 US claimed
WO-2011157778-A1 ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDE AND ACARICIDE PROPERTIES BAYER CROPSCIENCE AG (DE) 2011-12-22 WO claimed
US-20250302039-A1 USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS CLARIANT INTERNATIONAL LTD. (CH) 2025-10-02 US disclosed
US-11700852-B2 Aqueous electrolyte-containing adjuvant compositions, active ingredient-containing compositions and the use thereof CLARIANT INTERNATIONAL LTD (CH) 2023-07-18 US disclosed
EP-3556211-B1 ORGANIC AMMONIUM SALTS OF ANIONIC PESTICIDES CLARIANT INT LTD (CH) 2023-01-25 EP disclosed
CN-107205379-B Aqueous adjuvant composition containing electrolyte, composition containing active ingredient and use thereof 科莱恩国际有限公司 2021-08-10 CN disclosed
CN-107072192-B Organic ammonium salts of anionic pesticides 科莱恩国际有限公司 2021-08-06 CN disclosed
EP-3232780-B1 AQUEOUS ELECTROLYTE-CONTAINING ADJUVANT COMPOSITIONS, ACTIVE INGREDIENT-CONTAINING COMPOSITIONS AND THE USE THEREOF CLARIANT INT LTD (CH) 2021-08-04 EP disclosed
CN-112120036-A Use of acylsulfonamides for increasing plant yield 拜耳作物科学股份公司 2020-12-25 CN disclosed
US-20200323206-A1 USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS CLARIANT INTERNATIONAL LTD. (CH) 2020-10-15 US disclosed
WO-2012089721-A1 USE OF SUBSTITUTED SPIROCYCLIC SULFONAMIDOCARBOXYLIC ACIDS, CARBOXYLIC ESTERS THEREOF, CARBOXAMIDES THEREOF AND CARBONITRILES THEREOF OR SALTS THEREOF FOR ENHANCEMENT OF STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AG (DE) 2012-07-05 WO disclosed
EP-2471363-A1 Use of aryl-, heteroaryl- and benzylsulfonamide carboxylic acids, -carboxylic acid esters, -carboxylic acid amides and -carbonitriles and/or its salts for increasing stress tolerance in plants Bayer CropScience AG (DE) 2012-07-04 EP disclosed
WO-2012000896-A2 HETEROCYCLIC COMPOUNDS AS AGENTS FOR PEST CONTROL BAYER CROPSCIENCE AG (DE) 2012-01-05 WO disclosed
US-20110319428-A1 THIAZOLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2011-12-29 US disclosed
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2011-12-22 US disclosed
WO-2011138285-A1 THIAZOL DERIVATIVES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2011-11-10 WO disclosed
WO-2011107504-A1 FLUOROALKYL-SUBSTITUTED 2-AMIDOBENZIMIDAZOLES AND THE USE THEREOF FOR BOOSTING STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AG (DE) 2011-09-09 WO disclosed
US-20110218103-A1 Fluoroalkyl-substituted 2-amidobenzimidazoles BAYER CROPSCIENCE AG (DE) 2011-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200323206-A1 USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS HMBS, PAH, HPD KDR 2918/4885LCK 4381/4885MET 412/4885
US-20250302039-A1 USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS NPEPPS, NAPEPLD, NANP KDR 3833/4885LCK 4277/4885MET 4239/4885
US-11700852-B2 Aqueous electrolyte-containing adjuvant compositions, active ingredient-containing compositions and the use thereof AQP1, PHOSPHO1, AQP3 KDR 3825/4885LCK 17/4885MET 4096/4885
US-20110218103-A1 Fluoroalkyl-substituted 2-amidobenzimidazoles BOLA2; BOLA2B, ARFIP2, PFAS KDR 3144/4885LCK 3273/4885MET 3040/4885
US-20110319428-A1 THIAZOLE DERIVATIVES AS PESTICIDES DDT, PTMS, TARS2 KDR 4339/4885LCK 2612/4885MET 3456/4885
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties ACHE, ACAT1, ACAT2 KDR 4568/4885LCK 3664/4885MET 4784/4885
US-20160037775-A1 ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES ACHE, ACAT1, ACAT2 KDR 4568/4885LCK 3664/4885MET 4784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.