Sugi Predict

Sugi Predict / Compounds / SCHEMBL2860586

SCHEMBL2860586

SCHEMBL2860586

O=S(=O)(Oc1ccccc1Br)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 2/20 0.42
▸ CA2 P00918 2/20 0.42
▸ CA5A P35218 1/20 0.42
▸ CA9 Q16790 1/20 0.42
▸ DRD2 P14416 7/20 0.39
▸ DRD3 P35462 5/20 0.39
▸ DRD4 P21917 3/20 0.39
▸ DRD1 P21728 1/20 0.39
▸ DRD5 P21918 1/20 0.39
▸ CA4 P22748 1/20 0.36
▸ CA6 P23280 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ ELANE P08246 1/20 0.36
▸ HTR1D P28221 2/20 0.36
▸ HTR5A P47898 1/20 0.35
▸ EPAS1 Q99814 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31265243 1.00 CA1 (0.42) CA1CA2CA5ACA9DRD2
SCHEMBL1712875 0.86 DRD2 (0.43) CA1CA2CA5ACA9DRD2
SCHEMBL7023211 0.80 DRD2 (0.42) CA1CA2CA5ACA9DRD2
SCHEMBL21313423 0.79 PKM (0.43) CA1CA2CA5ACA9DRD2
SCHEMBL6937413 0.78 HSD11B1 (0.50) CA1CA2CA5ACA9DRD2
SCHEMBL776669 0.78 DRD2 (0.40) DRD2DRD3DRD4DRD1DRD5
SCHEMBL16926997 0.78 DRD2 (0.41) CA1CA2CA5ACA9DRD2
SCHEMBL7785330 0.78 EPAS1 (0.39) CA1CA2DRD2DRD3DRD4
SCHEMBL31444250 0.78 ELANE (0.59) CA1CA2CA5ACA9CA4
SCHEMBL20193401 0.78 EPAS1 (0.37) CA1CA2DRD2DRD3DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852159-A Heterogeneous palladium-catalyzed selective bell wood coupling reaction and application thereof in Wilmofini intermediate synthesis 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2024-10-29 — — CN disclosed
US-20240158424-A1 METHOD FOR PRODUCING DIPHOSPHINE MONOXIDE TAKASAGO INTERNATIONAL CORPORATION (JP) 2024-05-16 — — US disclosed
EP-4361162-A2 METHOD FOR PRODUCING DIPHOSPHINE MONOXIDE Takasago International Corporation (JP) 2024-05-01 — — EP disclosed
CN-111868052-B Phenyl pyrrolidone formyl peptide 2 receptor agonist 百时美施贵宝公司 2024-03-08 — — CN disclosed
US-11708327-B2 Phenylpyrrolidinone formyl peptide 2 receptor agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2023-07-25 — — US disclosed
US-20220127251-A1 PROCESS FOR THE PRODUCTION OF ARYLAMINES MERCK PATENT GMBH (DE) 2022-04-28 — — US disclosed
EP-3981767-A1 PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS Bristol-Myers Squibb Company (US) 2022-04-13 — — EP disclosed
EP-3762380-B1 PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS BRISTOL MYERS SQUIBB CO (US) 2021-12-15 — — EP disclosed
US-20210371378-A1 PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS BRISTOL MYERS SQUIBB CO (US) 2021-12-02 — — US disclosed
US-11117861-B2 Phenylpyrrolidinone formyl peptide 2 receptor agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2021-09-14 — — US disclosed
US-20030139285-A1 Novel asymmetric phosphine ligand TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-07-24 — — US disclosed
EP-1318156-A1 Novel asymmetric phosphine ligand Takasago International Corporation (JP) 2003-06-11 — — EP disclosed
EP-1318155-A1 Novel asymmetric phosphine ligand Takasago International Corporation (JP) 2003-06-11 — — EP disclosed
EP-1312605-A1 Method for producing biaryl compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-05-21 — — EP disclosed
CN-1103329-C Ethynyl substituted aromatic compounds, their synthesis, polymers and uses thereof DOW CHEMICAL CO (US) 2003-03-19 — — CN disclosed
EP-0854849-B1 ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF DOW CHEMICAL CO (US) 2001-10-31 — — EP disclosed
US-6121495-A Ethynyl substituted aromatic compounds, synthesis, polymers and uses thereof THE DOW CHEMICAL COMPANY (US) 2000-09-19 — — US disclosed
CN-1199389-A Ethynyl substituted aromatic compounds, their synthesis, polymers and uses thereof DOW CHEMICAL CO (US) 1998-11-18 — — CN disclosed
EP-0854849-A1 ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF THE DOW CHEMICAL COMPANY (US) 1998-07-29 — — EP disclosed
WO-1997010193-A1 ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF THE DOW CHEMICAL COMPANY (US) 1997-03-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158424-A1 METHOD FOR PRODUCING DIPHOSPHINE MONOXIDE TDO2, SCO2, DUOX1 CA1 851/4885CA2 388/4885CA5A 167/4885
US-11708327-B2 Phenylpyrrolidinone formyl peptide 2 receptor agonists FPR1, FPR2, FPR3 CA1 4616/4885CA2 3429/4885CA5A 3280/4885
US-20220127251-A1 PROCESS FOR THE PRODUCTION OF ARYLAMINES MAOB, TYR, INMT CA1 4511/4885CA2 3284/4885CA5A 2431/4885
US-11117861-B2 Phenylpyrrolidinone formyl peptide 2 receptor agonists FPR1, FPR2, FPR3 CA1 4616/4885CA2 3429/4885CA5A 3280/4885
US-20030139285-A1 Novel asymmetric phosphine ligand PHOSPHO1, PAPSS1, PPM1F CA1 776/4885CA2 1670/4885CA5A 2835/4885
US-20210371378-A1 PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS FPR1, FPR2, FPR3 CA1 4616/4885CA2 3429/4885CA5A 3280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.